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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1100-1150 of 2567 product results
Insulin (rHuInsulin), Active Protein (Cat# AAA47953)
Full Name
Recombinant Human Insulin
Gene Names
INS; ILPR; IRDN; IDDM2; MODY10
Purity
Greater than 98% by RP-HPLC and SDS-PAGE.
Pricing
Neuritin, Active Protein (Cat# AAA75585)
Full Name
Neuritin protein
Gene Names
NRN1; NRN; dJ380B8.2
Purity
> 98% as determined by SDS-PAGE and HPLC
Pricing
Insulin receptor (CD220), Active Protein (Cat# AAA76108)
Full Name
Human Insulin receptor Recombinant (CD220)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
IL-3 receptor (CD123), Active Protein (Cat# AAA76117)
Full Name
Human IL-3 receptor Recombinant (CD123)
Purity
>97%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(SARS COV-2 Spike S RBD-human Fc HPLCThe purity of 2019-nCoV Spike RBD Fc is greater than 95% as determined by SEC-HPLC.)
2019 nCoV/COVID19 RBD, Active Protein (Cat# AAA76380)
Full Name
2019 nCoV/COVID19 RBD Recombinant-hFc
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(RGS18-/- mice present a defective megakaryopoiesis.Lin- bone marrow cells (5×104 cells/chamber) from 9/10-week-old WT and RGS18-/- mice (n?=?5 per group) were cultured in Mega-Cult-C media containing 50 ng/mL rhTPO, 10 ng/ml rmIL3, and 3 ng/ml rmIL6 in double-chamber slides at 37°C for 11 days.)
Thrombopoietin, Active Protein (Cat# AAA76396)
Full Name
mouse Thrombopoietin Recombinant
Gene Names
Thpo; Ml; Tpo; Mgdf; Tpo1; Tpo2; Tpo3; Tpo4; Mpllg
Purity
>95%, as determined by SDS-PAGE and HPLC.
Pricing
BAFF, Active Protein (Cat# AAA76585)
Full Name
BAFF Human
Reactivity
Human
Purity
>95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis bySDS-PAGE.
(a) Analysis by RP-HPLC.
(b) Analysis bySDS-PAGE.
Pricing
Microtubule-associated tau (MAPT), Active Protein (Cat# AAA244040)
Full Name
Recombinant Human Microtubule-associated protein tau (MAPT)
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
COVID 19 Spike Protein (S) D614G Coronavirus, Active Protein (Cat# AAA243741)
Full Name
Recombinant Human Novel Coronavirus Spike glycoprotein(S) (D614G), partial (Active)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EphA6 at 1 ug/ml (100 ul/well) can bind human EphrinA3 / Fc Chimera. The EC50 of human EphrinA3 is 299.2 ng/mL.)
Ephrin A3, Active Protein (Cat# AAA257840)
Full Name
Ephrin A3 Protein, Human, Recombinant (hFc Tag)
Gene Names
EFNA3; EFL2; EPLG3; LERK3; Ehk1-L
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Myostatin (MSTN), Active Protein (Cat# AAA148194)
Full Name
Active Myostatin (MSTN)
Gene Names
MSTN; GDF8; MSLHP
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Bioactivity
(Figure. The binding activity of HGF with HSPG.)
Hepatocyte Growth Factor, Active Protein (Cat# AAA150052)
Full Name
Active Hepatocyte Growth Factor (HGF)
Gene Names
HGF; SF; HGFB; HPTA; F-TCF; DFNB39
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Application Data
(Figure. Cell proliferation of Raji cells after stimulated with IL6.)
Interleukin 6, Active Protein (Cat# AAA150063)
Full Name
Active Interleukin 6 (IL6)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(The dose-effect curve of PRL was shown in Figure 2. It was obvious that PRL significantly promoted cell proliferation of MCF-7 cells. The ED50 for this effect is typically 3.709 to 8.973 ng/mL.Figure. The dose-effect curve of PRL on MCF-7 cells.)
Prolactin, Active Protein (Cat# AAA150103)
Full Name
Active Prolactin (PRL)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Figure.The chemotactic effect of SLC on Jurkat cells.)
Secondary Lymphoid Tissue Chemokine, Active Protein (Cat# AAA150110)
Full Name
Active Secondary Lymphoid Tissue Chemokine (SLC)
Gene Names
CCL21; ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Bioactivity
(Signal transducer and activator of transcription 3 (STAT3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT3 is phosphorylated by receptor-associated Janus kinases (JAK), form homo- or heterodimers, and translocate to the cell nucleus where they act as transcription activators. The protein can mediate the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. STAT3 is essential for the differentiation of the TH17 helper T cells, which have been implicated in a variety of autoimmune diseases. Besides, Glucose 7 Phosphate Isomerase (GPI) has been identified as an interactor of STAT3, thus a binding ELISA assay was conducted to detect the interaction of recombinant bovine STAT3 and recombinant human GPI. Briefly, STAT3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to GPI-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-STAT3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of STAT3 and GPI was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of STAT3 with GPI.)
Signal Transducer And Activator Of Transcription 3, Active Protein (Cat# AAA150116)
Full Name
Active Signal Transducer And Activator Of Transcription 3 (STAT3)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Application Data
(Tissue Factor Pathway Inhibitor 2 (TFPI2) takes part in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. TFPI2 does not have any influence on thrombin. TFPI2 also can inhibit MMP activity, which can hydrolyze gelatin under certain conditions. Thus, the activity of TFPI2 can be measured by inhibit MMP-2 hydrolyze gelatin. Gelatin zymography is mainly used for the detection of the gelatinases, 2g/mL was denatured by SDS loading buffer, electrophoresed through sodium dodecylsulphate–polyacrylamide gel (SDS–PAGE; 8%gels) containing gelatin (1mg/mL) with nonreducing conditions. After renaturation, incubate with various concentrations of recombinant human TFPI2, then staining with coomassie brilliant blue G250, active MMP-2 would hydrolyze gelatin nearby, which was indicated by the white binds on the gel; if the activity of MMP-2 inhibit by TFPI2, there was none white binds on the gel. The result was shown in figure 1.As the figure1 shown, MMP-2 can be inhibited by recombinant human TFPI2 at least 5g/mL.)
Tissue Factor Pathway Inhibitor 2, Active Protein (Cat# AAA150119)
Full Name
Active Tissue Factor Pathway Inhibitor 2 (TFPI2)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
WB (Western Blot)
(Figure. Western Blot)
Fibronectin Type III Domain Containing Protein 5, Active Protein (Cat# AAA150148)
Full Name
Active Fibronectin Type III Domain Containing Protein 5 (FNDC5)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
WB (Western Blot)
(Western BlotSample: Recombinant FGF18, Human;Antibody: Rabbit Anti- Human FGF18 Ab)
Fibroblast Growth Factor 18 (FGF18), Active Protein (Cat# AAA150332)
Full Name
Active Fibroblast Growth Factor 18 (FGF18)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
Application Data
TFF1, Active Protein (Cat# AAA214281)
Full Name
Recombinant Human TFF1
Gene Names
TFF1; pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
Purity
>95% as determined by SDS-PAGE
Pricing
SDS-PAGE
(SDS-PAGE)
Acid Sphingomyelinase (ASM), Active Protein (Cat# AAA152332)
Full Name
Active Acid Sphingomyelinase (ASM)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Cell proliferation of TF-1 cells after stimulated with IL4.)
Interleukin 4 (IL4), Active Protein (Cat# AAA152970)
Full Name
Active Interleukin 4 (IL4)
Gene Names
IL4; IL-4; BSF-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
(FLT-1 Sandwich ELISA using recombinant human soluble FLT-1 as standard . Mouse anti-human FLT-1 #EWI was used as capture antibody, Biotinylated rabbit anti-human FLT-1 was used for detection)
VEGFR-1/Flt-1 (native), soluble, Active Protein (Cat# AAA79126)
Full Name
Human VEGFR-1/Flt-1 (native), soluble
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
PlGF, Active Protein (Cat# AAA79130)
Full Name
Mouse PlGF
Gene Names
Pgf; PIGF; Plgf; AI854365
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
FGF-2 (basic), Active Protein (Cat# AAA79132)
Full Name
Human FGF-2 (basic)
Gene Names
FGF2; BFGF; FGFB; FGF-2; HBGF-2
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
VEGF-C, Active Protein (Cat# AAA79143)
Full Name
Human VEGF-C
Gene Names
VEGFC; VRP; Flt4-L
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
FGF-2 (basic), Active Protein (Cat# AAA79146)
Full Name
Human FGF-2 (basic)
Gene Names
FGF2; BFGF; FGFB; FGF-2; HBGF-2
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
MIA (Melanoma inhibitory activity), Active Protein (Cat# AAA79186)
Full Name
Human MIA (Melanoma inhibitory activity)
Gene Names
MIA; CD-RAP
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
Application Data
FGF-2 (basic), Active Protein (Cat# AAA79191)
Full Name
Mouse FGF-2 (basic)
Gene Names
Fgf2; Fgfb; bFGF; Fgf-2
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & silver stain
Pricing
FGF-2 (basic) 146 aa, Active Protein (Cat# AAA79192)
Full Name
Human FGF-2 (basic) 146 aa
Gene Names
FGF2; BFGF; FGFB; FGF-2; HBGF-2
Reactivity
Human
Purity
> 98% by SDS-PAGE & Silver stain
Pricing
Heregulin beta-1, Active Protein (Cat# AAA79196)
Full Name
Human Heregulin beta-1
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
Application Data
IL-6, Active Protein (Cat# AAA79198)
Full Name
Human IL-6
Gene Names
IL6; HGF; HSF; BSF2; IL-6; IFNB2
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
VEGF164, Active Protein (Cat# AAA79200)
Full Name
Mouse VEGF164
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
VEGFR-1/Flt-1(D7)-Fc Chimera, soluble, Active Protein (Cat# AAA79201)
Full Name
Human VEGFR-1/Flt-1(D7)-Fc Chimera, soluble
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Application Data
VEGFR-1/Flt-1 (D4), soluble, Active Protein (Cat# AAA79219)
Full Name
Human VEGFR-1/Flt-1 (D4), soluble
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
BAFF receptor, soluble, Active Protein (Cat# AAA79224)
Full Name
Human BAFF receptor, soluble
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Reactivity
Human
Purity
> 95% by SDS-PAGE and HPLC analyses
Pricing
Application Data
VEGF189, Active Protein (Cat# AAA79232)
Full Name
Human VEGF189
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
FGF-23, Active Protein (Cat# AAA79235)
Full Name
Recombinant Mouse FGF-23
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing
IL-23, Active Protein (Cat# AAA79249)
Full Name
Human IL-23
Gene Names
IL23A; P19; SGRF; IL-23; IL-23A; IL23P19
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing
Galectin-1, Active Protein (Cat# AAA79251)
Full Name
Human Galectin-1
Gene Names
LGALS1; GBP; GAL1
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
Application Data
FGF-10, Active Protein (Cat# AAA79268)
Full Name
Human FGF-10
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
VEGF144, Active Protein (Cat# AAA79270)
Full Name
Mouse VEGF144
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
DLL-4, soluble, Active Protein (Cat# AAA79284)
Full Name
Human DLL-4, soluble
Gene Names
DLL4; hdelta2
Purity
> 95%, by SDS-PAGE and HPLC analysis
Pricing
Application Data
EGF, Active Protein (Cat# AAA79304)
Full Name
Human EGF
Gene Names
EGF; URG; HOMG4
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Human Phosphoglycerate Mutase B Isozyme, Active Protein (Cat# AAA78964)
Full Name
Human Phosphoglycerate Mutase B Isozyme (rPGAM-B (human))
Purity
Single major band of 29kDa (1 mg protein loaded in SDS-PAGE)
Pricing
Thioredoxin Reductase, Active Protein (Cat# AAA78972)
Full Name
Thioredoxin Reductase (yeast) (rNTR (yeast))
Purity
>95% as determined by SDS-PAGE stained with CBBR.
Pricing
IFN-gamma, Active Protein (Cat# AAA79149)
Full Name
Mouse IFN-gamma
Gene Names
Ifng; Ifg; IFN-g
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
Application Data
FGF-2 (basic), Active Protein (Cat# AAA79158)
Full Name
Mouse FGF-2 (basic)
Gene Names
Fgf2; Fgfb; bFGF; Fgf-2
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
PDGF-AB, Active Protein (Cat# AAA79163)
Full Name
Human PDGF-AB
Gene Names
PDGFA; PDGF1; PDGF-A
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.