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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 2500-2550 of 2567 product results
Bioactivity
(HTRF assay for AMPK Complex (A2+B2+G1) activity 1 uM STK S1 substrate was incubated with different concentrations of AMPK Complex (A2+B2+G1) protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 50 uM AMP and 100 ul ATP for 1 hr. The 10 ul detection reagents containing anti-STK antibody (1:100) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
AMPK Complex (A2+B2+G1), Active Protein (Cat# AAA60319)
Full Name
Recombinant AMPK Complex (A2+B2+G1) protein
Purity
>=90%
Pricing
Alkaline Phosphatase, Active Protein (Cat# AAA11488)
Full Name
Alkaline Phosphatase (ALP), Human Placental
Purity
Purified
Pricing
SDS-PAGE
COVID 19 Spike Protein, Biotinylated (RBD-SD1, Avi) Coronavirus, Active Protein (Cat# AAA22155)
Full Name
Recombinant 2019-nCoV Spike Protein (RBD-SD1, Avi-His Tag)(Active)
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing
Mucin 16, Active Protein (Cat# AAA14758)
Full Name
Mucin 16, Recombinant, Human (CA125, FLJ14303, Ovarian Carcinoma Antigen CA 125)
Gene Names
MUC16; CA125
Purity
Purified
90% as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: <1EU/ug protein (LAL)
90% as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: <1EU/ug protein (LAL)
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
ALDH2, Active Protein (Cat# AAA11764)
Full Name
ALDH2,18-517aa, Human, E Coli (Bioactivity Validated)
Gene Names
ALDH2; ALDM; ALDHI; ALDH-E2
Reactivity
Human
Applications
SDS-PAGE, Enzyme Activity
Purity
> 90% by SDS-PAGE
Pricing
Alkaline Phosphatase, Active Protein (Cat# AAA11487)
Full Name
Alkaline Phosphatase (CIP/CIAP), Calf Intestinal
Purity
Purified
Pricing
Human Alanine Aminotransferase, Active Protein (Cat# AAA14927)
Full Name
Recombinant Human Alanine Aminotransferase Glutamie-Pyruvic Transaminase (EC 2.6.1.2)
Pricing
Matrix Metalloproteinase-3, Active Protein (Cat# AAA10817)
Full Name
Recombinant Human Matrix Metalloproteinase-3, HEK
Gene Names
MMP3; SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
Streptokinase, Active Protein (Cat# AAA10820)
Full Name
Recombinant Streptokinase
Purity
Greather than 97% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE
Pricing
Trefoil Factor-3, Active Protein (Cat# AAA10881)
Full Name
Recombinant Human Trefoil Factor-3
Gene Names
TFF3; ITF; P1B; TFI
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing
Sonic HedgeHog, Active Protein (Cat# AAA10853)
Full Name
Recombinant Mouse Sonic HedgeHog
Gene Names
Shh; Hx; Dsh; Hhg1; Hxl3; M100081; 9530036O11Rik
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing
Actin, beta Human, Active Protein (Cat# AAA14745)
Full Name
Actin, beta Human
Gene Names
ACTB; BRWS1; PS1TP5BP1
Applications
EL/EIA, WB
Purity
>99%. May contain traces of gamma-actin.
Pricing
WB (Western Blot)
(Western Blot: Spike RBD HIS Tag detected with Anti-HIS-Tag antibody HRP conjugate showing a band at approx. 30 kDa)
COVID 19 Spike Glycoprotein S1 RBD Coronavirus, Active Protein (Cat# AAA13473)
Full Name
Recombinant Human SARS-CoV-2 Spike Glycoprotein S1 RBD (HEK)
Purity
Affinity chromatography. Purity: >95% by SDS PAGE gel
Pricing
MHC class I chain-related gene B, Active Protein (Cat# AAA10837)
Full Name
Recombinant Human MHC class I chain-related gene B
Gene Names
MICB; PERB11.2
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Purity
(The purity of LRRK2 (I2020T) was determined to be >70% by densitometry, approx. MW 210 kDa.)
LRRK2, Active Protein (Cat# AAA14255)
Full Name
LRRK2 Mutant (I2020T), Active
Gene Names
LRRK2; PARK8; RIPK7; ROCO2; AURA17; DARDARIN
Purity
>70%
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
Alpha-enolase, Active Protein (Cat# AAA11794)
Full Name
Alpha-enolase, 1-434aa, Human, E Coli (Bioactivity Validated)
Gene Names
ENO1; NNE; PPH; MPB1; ENO1L1; HEL-S-17
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Application Data
(Immobilized Recombinant SARS-CoV-2 Envelope at 2ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 Nucleocapsid with a linear range of 1.2-41.1 ng/mL.)
COVID 19 Envelope Coronavirus, Active Protein (Cat# AAA28309)
Full Name
Recombinant SARS-CoV-2 Envelope Protein
Purity
> 95% by SDS-PAGE.
Pricing
Application Data
(Measurements of kinetic parameters of Recombinant 2019-nCoV 3C-like Proteinase (CAT# AAA27964) (For reference only).)
COVID 19 3C-like Proteinase Coronavirus, Active Protein (Cat# AAA27964)
Full Name
Recombinant 2019-nCoV 3C-like Proteinase (N-6His) (CR76)
Purity
> = 95% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Pricing
HIV-1 env gp120, Strain YU2, Active Protein (Cat# AAA14753)
Full Name
HIV-1 env gp120, Strain YU2 (M Tropic), Recombinant (Human Immunodeficiency Virus-1)
Applications
Western Blot
Purity
>95% (SDS-PAGE, reduced). Purified by immunoaffinity chromatography.
Pricing
SDS-PAGE
(10% SDS-PAGE Coomassie staining. Lane 1: 3ug F4600-21. Lane 2: Protein Marker.)
Flt3, active, N-terminal His tag Receptor Tyrosine Kinase, Active Protein (Cat# AAA14760)
Full Name
Flt3, active, Recombinant, Human, N-terminal His tag Receptor Tyrosine Kinase (Fms-like Tyrosine Kinase 3, CD135)
Gene Names
Fiz1; AI790204; mFLJ00416
Reactivity
Human
Purity
> 80% by SDS-PAGE.
Pricing
Application Data
(3CL Proteinase inhibitor screening using 2019-nCoV 3CL MPro Recombinant Protein Provided by customer.)
COVID 19 3CL MPro Coronavirus, Active Protein (Cat# AAA27953)
Full Name
2019-nCoV 3CL MPro Recombinant Protein
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Pricing
SDS-PAGE
COVID 19 Spike S1 Protein Coronavirus, Active Protein (Cat# AAA22156)
Full Name
Recombinant 2019-nCoV S1 Protein
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing
Hypoxanthine-Guanine Phosphoribosyltransferase, Active Protein (Cat# AAA10904)
Full Name
Recombinant Human Hypoxanthine-Guanine Phosphoribosyltransferase, Active
Gene Names
HPRT1; HPRT; HGPRT
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
5-Lipoxygenase, Active Protein (Cat# AAA14373)
Full Name
5-Lipoxygenase protein
Gene Names
ALOX5; 5-LO; 5LPG; LOG5; 5-LOX
Pricing
Purity
(The purity of RIPK1 was determined to be >70% by densitometry, approx. MW 108 kDa.)
HIV1 tat, Active Protein (Cat# AAA14384)
Full Name
HIV1 tat protein
Applications
Western Blot
Purity
> 99% by SDS-PAGE and HPLC
Pricing
SDS-PAGE
(SDS-PAGE of 78 kDa Grp78 (BiP) protein (AAA17807))
Grp78 (Bip), Active Protein (Cat# AAA17807)
Full Name
Recombinant Human GRP78 (Bip)
Gene Names
HSPA5; BIP; MIF2; GRP78; HEL-S-89n
Applications
Western Blot
Purity
Affinity Purified
Pricing
SDS-PAGE
(The purity of PAD4 was determined to be >95% by densitometry. Approx. MW 96 kDa.)
Application Data
HDAC4, Active Protein (Cat# AAA14763)
Full Name
HDAC4, Recombinant, Human (Histone Deacetylase 4)
Purity
> 89%
Pricing
Application Data
(Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures such as those in tau fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift, and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) in tau K18 P301L monomers over time. Thioflavin T ex = 450 nm, em = 485 nm.)
Tau, Active Protein (Cat# AAA27662)
Full Name
Active Human Recombinant Tau (K18), P301L Mutant Protein Monomer
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103
Applications
Western Blot
Purity
Purity: >95%
Purification: Ion-exchange Purified
Purification: Ion-exchange Purified
Pricing
Application Data
(Fig. 1. Purified CHO derived rhHPA1 was analyzed by:A. Western blot analysis using Polyclonal rabbit anti-HPA1 antibodiesB. SDS-PAGE/GelCode Blue stainingC. RPHPLC; 1, 8-kDa subunit; 2, 50-kDa subunit.)
Heparanase-1, Active Protein (Cat# AAA10906)
Full Name
Recombinant Human Heparanase-1 Active
Purity
> 95% on SDS-PAGE (Fig. 1, B)
> 95% on RP-HPLC (Fig. 1, C)
> 95% on RP-HPLC (Fig. 1, C)
Pricing
SCF, Active Protein (Cat# AAA14382)
Full Name
SCF protein (Mouse)
Gene Names
KITLG; SF; MGF; SCF; FPH2; FPHH; KL-1; Kitl; SHEP7
Purity
> 98% pure
Pricing
SDS-PAGE
(SDS-PAGE of ~67 kDa Human Tau Protein 2N4R P301S Preformed Fibrils. Lane 1: MW Ladder. Lane 2: Tau Protein Preformed Fibrils)
Tau441, Active Protein (Cat# AAA27663)
Full Name
Active Human Recombinant Tau441 (2N4R), P301S Mutant Protein Preformed Fibrils
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103
Applications
Western Blot
Purity
>95%
Ion-Exchange Purified
Ion-Exchange Purified
Pricing
Biological Activity
(Human TNF-alpha induces cell cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D.)
Tumor Necrosis Factor-alpha, Active Protein (Cat# AAA11742)
Full Name
Tumor Necrosis Factor-alpha, 77-233 aa, Human, E Coli (Bioactivity Validated)
Gene Names
TNF; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Applications
SDS-PAGE, Bioactivity
Purity
> 95% by SDS-PAGE
Pricing
BAFF, Active Protein (Cat# AAA14391)
Full Name
BAFF Receptor protein
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Purity
> 95% pure
Pricing
Application Data
(Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures such as those in alpha synuclein fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift and increased fluorescence intensity. Thioflavin T emission curves show a limited increase in fluorescence (correlated to alpha synuclein aggregation) over time in A53T alpha synuclein monomers . A much greater increase in fluorescence is seen when 100 uM monomer is combined with 10 nM of fibrils (AAA27661) as the fibrils seed the formation of new fibrils from the pool of active monomers. Thioflavin T ex = 450 nm, em = 485 nm.)
A53T Mutant Alpha Synuclein, Active Protein (Cat# AAA27661)
Full Name
Active Human Recombinant A53T Mutant Alpha Synuclein Protein Preformed Fibrils (Type 1)
Gene Names
SNCA; PD1; NACP; PARK1; PARK4
Applications
Western Blot
Purity
>95% pure using SDS-PAGE analysis.
Ion-Exchange Purified
Ion-Exchange Purified
Pricing
SDS-PAGE
KLK4, Active Protein (Cat# AAA27762)
Full Name
KLK4 Protein, Human, Recombinant (His Tag)
Gene Names
KLK4; ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; MGC116827; MGC116828
Purity
>94% as determined by SDS-PAGE
Pricing
CD137L, Active Protein (Cat# AAA14390)
Full Name
CD137L protein
Gene Names
TNFSF9; CD137L; 4-1BB-L
Purity
> or = 98% by SDS-PAGE gel and HPLC analysis
Pricing
Cancer Antigen 15-3, Active Protein (Cat# AAA11498)
Full Name
Cancer Antigen 15-3 (CA 15-3)
Gene Names
MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC
Purity
Control grade
Pricing
SDS-PAGE
C-type lectin domain family 4 member C, Active Protein (Cat# AAA18755)
Full Name
Recombinant Human C-type lectin domain family 4 member C
Gene Names
CLEC4C; DLEC; HECL; BDCA2; CD303; CLECSF7; CLECSF11; PRO34150
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Activity
Proteinase K (PROK), Active Protein (Cat# AAA27052)
Full Name
Recombinant Tritirachium album Proteinase K (PROK) (Active)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
WB (Western Blot)
(Positive WB detected in: His tag-tagged SARS-CoV-2 nucleocapsid recombinant protein from E. Coli SARS-CoV-2 nucleocapsid antibody at 1:1000; Secondary; Peroxidase-Affinipure Goat Anti-Human IgG, Fc? Fragment Specific at 1/20000 dilution; Predicted band size: 48 kDa; Observed band size: 55 kDa)
COVID 19 Nucleocapsid (NP) Coronavirus, Active Protein (Cat# AAA27032)
Full Name
Recombinant Human Novel Coronavirus Nucleoprotein (N)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
(Proliferation assay with TF-I cells.)
SCF, Active Protein (Cat# AAA14944)
Full Name
Mouse SCF
Gene Names
Kitl; Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
SDS-PAGE
(SDS-PAGE analysis of PTP1B (3ug protein; 12% gel) using P9109-14.)
Protein Tyrosine Phosphatase 1B, Active Protein (Cat# AAA14754)
Full Name
Protein Tyrosine Phosphatase 1B, Recombinant, Human (PTP1B)
Gene Names
PTPN1; PTP1B
Purity
Highly Purified
>95% by SDS PAGE; Purified by using conventional chromatography techniques.
>95% by SDS PAGE; Purified by using conventional chromatography techniques.
Pricing
SDS-PAGE
Transmembrane protease serine 2 (TMPRSS2), Active Protein (Cat# AAA18665)
Full Name
Recombinant Human Transmembrane protease serine 2 (TMPRSS2), partial
Gene Names
TMPRSS2; PP9284; PRSS10
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
SDS-PAGE
uPAR / CD87, Active Protein (Cat# AAA22094)
Full Name
Recombinant Human uPAR Protein (His Tag)(Active)
Gene Names
PLAUR; CD87; UPAR; URKR; U-PAR
Purity
> 98 % as determined by reducing SDS-PAGE.
Pricing
SDS-PAGE
Lymphocyte antigen 6 complex locus protein G6d (LY6G6D), Active Protein (Cat# AAA18703)
Full Name
Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D)
Gene Names
LY6G6D; G6D; NG25; LY6-D; MEGT1; C6orf23
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
TNFRSF1B, Active Protein (Cat# AAA23888)
Full Name
Recombinant Human TNFRSF1B
Gene Names
TNFRSF1B; p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Purity
>95% as determined by SDS-PAGE
Pricing
Complement C9, Active Protein (Cat# AAA14378)
Full Name
Complement C9 protein
Gene Names
C9; C9D; ARMD15
Purity
> 95% pure
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.