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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 700-750 of 2567 product results

E Coli GAL1 Active Protein – Cat# AAA153031 – Bioactivity
E Coli GAL1 Active Protein – Cat# AAA153031 – Bioactivity Bioactivity (Figure 2. The hemagglutination assay of GAL1 in V- bottom shaped 96-well microtiter plate.)

Galectin 1 (GAL1), Active Protein (Cat# AAA153031)

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Full Name
Active Galectin 1 (GAL1)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
293F Cell VCAM1 Active Protein – Cat# AAA153038 – Bioactivity
293F Cell VCAM1 Active Protein – Cat# AAA153038 – Bioactivity Bioactivity (Vascular cell adhesion protein 1 (VCAM-1) is a cell adhesion molecule and a member of the immunoglobulin superfamily. Alternatively spliced forms are known to occur, but the most common form is a type I transmembrane protein with a 674 amino acid extracel)

Vascular Cell Adhesion Molecule 1 (VCAM1), Active Protein (Cat# AAA153038)

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Full Name
Active Vascular Cell Adhesion Molecule 1 (VCAM1)
Gene Names
VCAM1; CD106; INCAM-100
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli IL1B Active Protein – Cat# AAA153046 – Bioactivity
E Coli IL1B Active Protein – Cat# AAA153046 – Bioactivity Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153046)

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Full Name
Active Interleukin 1 Beta (IL1b)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli SOD2 Active Protein – Cat# AAA153068 – Bioactivity
E Coli SOD2 Active Protein – Cat# AAA153068 – Bioactivity Bioactivity (Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide r)

Superoxide Dismutase 2, Mitochondrial (SOD2), Active Protein (Cat# AAA153068)

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Full Name
Active Superoxide Dismutase 2, Mitochondrial (SOD2)
Gene Names
Sod2; MnSOD; Sod-2
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli MRP1 Active Protein – Cat# AAA153071 – Bioactivity
E Coli MRP1 Active Protein – Cat# AAA153071 – Bioactivity Bioactivity (Motility Related Protein (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. It can enable ATPase-coupled inorganic anion transmembrane transporter activity. Involved in anion transmembrane transport ; renal tubular secretion)

Motility Related Protein (MRP1), Active Protein (Cat# AAA153071)

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Full Name
Active Motility Related Protein (MRP1)
Gene Names
CD9; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli DEFB1 Active Protein – Cat# AAA153082 – Bioactivity
E Coli DEFB1 Active Protein – Cat# AAA153082 – Bioactivity Bioactivity (Beta Defensin-1 (DEFB1) displays potent microcidal properties, and also plays a part in other aspects of innate and adaptive immunity. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater suscepti)

Defensin Beta 1 (DEFb1), Active Protein (Cat# AAA153082)

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Full Name
Active Defensin Beta 1 (DEFb1)
Gene Names
DEFB1; BD1; HBD1; DEFB-1; DEFB101
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
E Coli LAB7-1 Active Protein – Cat# AAA153084 – Bioactivity
E Coli LAB7-1 Active Protein – Cat# AAA153084 – Bioactivity Bioactivity (B-Lymphocyte Activation Antigen B7-1 (CD80) is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B)

B-Lymphocyte Activation Antigen B7-1 (LAB7-1), Active Protein (Cat# AAA153084)

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Full Name
Active B-Lymphocyte Activation Antigen B7-1 (LAB7-1)
Gene Names
Cd80; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli LBP Active Protein – Cat# AAA153087 – Bioactivity
E Coli LBP Active Protein – Cat# AAA153087 – Bioactivity Bioactivity (Lipopolysaccharide Binding Protein (LBP) is a soluble acute-phase protein that binds to bacterial lipopolysaccharide (or LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4.Thi)

Lipopolysaccharide Binding Protein (LBP), Active Protein (Cat# AAA153087)

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Full Name
Active Lipopolysaccharide Binding Protein (LBP)
Gene Names
Lbp; Ly88; Bpifd2
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli S100 Active Protein – Cat# AAA161650 – Bioactivity
E Coli S100 Active Protein – Cat# AAA161650 – Bioactivity Bioactivity (Small calcium binding protein that S100 Calcium Binding Protein (S100), also known as S100 Alpha (S100A1), is a member of the S100 family of calcium-binding proteins. As with most S100 proteins, S100A1 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and it possess a variety of intracellular and extracellular functions. They interact with multiple receptors and signal transducers to regulate pathways that govern inflammation, cell differentiation, proliferation, energy metabolism, apoptosis, calcium homeostasis, cell cytoskeleton and microbial resistance. S100 Calcium Binding Protein A4 (S100A4) is one of targets of S100A1. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human S100A1 and recombinant mouse S100A4. Briefly, S100A1 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to S100A4-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-S100A1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human S100A1 and recombinant mouse S100A4 was shown in Figure 1, the EC50 for this effect is 0.11 ug/mL.)

S100 Calcium Binding Protein (S100), Active Protein (Cat# AAA161650)

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Full Name
Active S100 Calcium Binding Protein (S100)
Gene Names
S100A1; S100; S100A; S100-alpha
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
293F Cell C Reactive Protein; CRP active protein (eukaryotic, 293F Cell), Mouse; C-RP; PTX1; Pentraxin-Related; Pentraxin 1 Active Protein – Cat# AAA161454 – SDS_PAGE
293F Cell C Reactive Protein; CRP active protein (eukaryotic, 293F Cell), Mouse; C-RP; PTX1; Pentraxin-Related; Pentraxin 1 Active Protein – Cat# AAA161454 – SDS_PAGE SDS_PAGE (Sample: Active recombinant CRP, Mouse)

C ReProtein (CRP), Active Protein (Cat# AAA161454)

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Full Name
Active C Reactive Protein (CRP)
Reactivity
Mus musculus (Mouse)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
TGFB2 Active Protein – Cat# AAA150085 – Bioactivity
TGFB2 Active Protein – Cat# AAA150085 – Bioactivity Bioactivity (Transforming growth factor-beta 2 (TGF-2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development (alternative names: Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin). It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Besides, Vitronectin (VTN) has been identified as an interactor of TGF-2, thus a binding ELISA assay was conducted to detect the interaction of recombinant rat TGF-2 and recombinant rat VTN. Briefly, TGF-2 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to VTN-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-TGF-2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TGF-2 and VTN was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of TGF-2 with VTN.)

Transforming Growth Factor Beta 2, Active Protein (Cat# AAA150085)

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Full Name
Active Transforming Growth Factor Beta 2 (TGFb2)
Gene Names
Tgfb2; TGF-B2
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
PKM2 Active Protein – Cat# AAA150096 – Bioactivity
PKM2 Active Protein – Cat# AAA150096 – Bioactivity Bioactivity (Figure. The binding activity of PKM2 with PIN1.Pyruvate Kinase, Muscle (PKM2) is one of four isozymes of pyruvate kinase. In vertebrates there are four isozymes of pyruvate kinase: L (liver), R (erythrocytes), M1 (muscles, hearts and brain) and M2 (only form detectable in early fetal tissue and present in most adult tissues). Pyruvate kinase is the enzyme that catalyzes the final step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP. Besides, Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting Protein 1 (PIN1) has been identified as an interactor of PKM2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PKM2 and recombinant human PIN1. Briefly, PKM2 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to PIN1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-PKM2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PKM2 and PIN1 was shown in Figure 1, and this effect was in a dose dependent manner.)

Pyruvate kinase isozymes M2, Active Protein (Cat# AAA150096)

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Full Name
Active Pyruvate kinase isozymes M2 (PKM2)
Gene Names
PKM; PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
NRG1 Active Protein – Cat# AAA150117 – Application Data
NRG1 Active Protein – Cat# AAA150117 – Application Data Application Data (The dose-effect curve of NRG1 was shown in Figure 2. It was obvious that NRG1 significantly promoted cell proliferation of MCF-7 cells. The ED50 for this effect is typically 5.240 to 9.112 ng/mL.Figure. The dose-effect curve of NRG1 on MCF-7 cells.)

Neuregulin 1, Active Protein (Cat# AAA150117)

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Full Name
Active Neuregulin 1 (NRG1)
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
FGF13 Active Protein – Cat# AAA150128 – Bioactivity
FGF13 Active Protein – Cat# AAA150128 – Bioactivity Bioactivity (Fibroblast growth factor 13 (FGF13) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. Besides, Prion Protein (PRNP) has been identified as an interactor of FGF13, thus a binding ELISA assay was conducted to detect the interaction of recombinant human FGF13 and recombinant human PRNP. Briefly, FGF13 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to PRNP-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-FGF13 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of FGF13 and PRNP was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of FGF13 with PRNP.)

Fibroblast Growth Factor 13, Active Protein (Cat# AAA150128)

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Full Name
Active Fibroblast Growth Factor 13 (FGF13)
Gene Names
FGF13; FGF2; FHF2; FHF-2; FGF-13; LINC00889
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
E. Coli COMT Active Protein – Cat# AAA150144 – WB (Western Blot)
E. Coli COMT Active Protein – Cat# AAA150144 – WB (Western Blot) WB (Western Blot) (Figure 3. Western BlotSample: Recombinant COMT, Human;Antibody: Rabbit Anti-Human COMT Ab)

Catechol-O-Methyltransferase, Active Protein (Cat# AAA150144)

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Full Name
Active Catechol-O-Methyltransferase (COMT)
Gene Names
COMT; HEL-S-98n
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
293F Cell IL10 Active Protein – Cat# AAA146605 – Application Data
293F Cell IL10 Active Protein – Cat# AAA146605 – Application Data Application Data

Interleukin 10 (IL10), Active Protein (Cat# AAA146605)

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Full Name
Active Interleukin 10 (IL10)
Gene Names
IL10; CSIF; TGIF; GVHDS; IL-10; IL10A
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
293F Cell IL4 Active Protein – Cat# AAA146608 – Application Data
293F Cell IL4 Active Protein – Cat# AAA146608 – Application Data Application Data

Interleukin 4 (IL4), Active Protein (Cat# AAA146608)

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Full Name
Active Interleukin 4 (IL4)
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
E Coli FNDC5 Active Protein – Cat# AAA146625 – Application Data
E Coli FNDC5 Active Protein – Cat# AAA146625 – Application Data Application Data

Fibronectin Type III Domain Containing Protein 5 (FNDC5), Active Protein (Cat# AAA146625)

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Full Name
Active Fibronectin Type III Domain Containing Protein 5 (FNDC5)
Gene Names
FNDC5; FRCP2; irisin
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Human IL7 Active Protein – Cat# AAA148140 – Application Data
Human IL7 Active Protein – Cat# AAA148140 – Application Data Application Data

Interleukin 7 (IL7), Active Protein (Cat# AAA148140)

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Full Name
Active Interleukin 7 (IL7)
Gene Names
IL7; IL-7
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
293F Cell IFNA Active Protein – Cat# AAA148155 – Application Data
293F Cell IFNA Active Protein – Cat# AAA148155 – Application Data Application Data

Interferon Alpha (IFNa), Active Protein (Cat# AAA148155)

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Full Name
Active Interferon Alpha (IFNa)
Gene Names
Ifna1; Ifa1
Reactivity
Mouse
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
E. Coli RNase A Active Protein – Cat# AAA150337 – Application Data
E. Coli RNase A Active Protein – Cat# AAA150337 – Application Data Application Data (Activity: Ribonuclease A (RNASEA) is a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNASEA cleaves RNA on the 3' side of pyrimidine nucleotides. The protein acts to degrade ds-RNA over ss-RNA. The activity of recombinant human RNASEA measured by cleaving yeast RNA. One unit of the enzyme causes an increase in absorbance of 0.001 at 260 nm in 15 min when yeast RNA is hydrolyzed at 50°C and pH 5.0. Pipette 50ulof respective recombinant human RNASEA dilution into 100ul 0.1M sodium acetate buffer, pH 5.0, then add 150ul of 0.15mg/ml yeast RNA. The blank tube use 50ul ultrapure water instead of enzyme dilution. All the all tubes Incubate at 50°C for 15 minutes. Read 260 verus blankCalculation)

Ribonuclease A (RNase A), Active Protein (Cat# AAA150337)

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Full Name
Active Ribonuclease A (RNase A)
Applications
Activity Assay, Cell Culture
Pricing
E Coli CXCL3 Active Protein – Cat# AAA214268 – Application Data
E Coli CXCL3 Active Protein – Cat# AAA214268 – Application Data Application Data

GRO gamma (CXCL3), Active Protein (Cat# AAA214268)

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Full Name
Recombinant Human GRO gamma (CXCL3)
Purity
>95% as determined by SDS-PAGE
Pricing
E Coli SHH Active Protein – Cat# AAA214271 – Application Data
E Coli SHH Active Protein – Cat# AAA214271 – Application Data Application Data

SHH, Active Protein (Cat# AAA214271)

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Full Name
Recombinant Human SHH
Gene Names
SHH; TPT; HHG1; HLP3; HPE3; SMMCI; ShhNC; TPTPS; MCOPCB5
Purity
>95% as determined by SDS-PAGE
Pricing
E Coli IL36B Active Protein – Cat# AAA214303 – Application Data
E Coli IL36B Active Protein – Cat# AAA214303 – Application Data Application Data

IL36B, Active Protein (Cat# AAA214303)

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Full Name
Recombinant Human IL36B
Gene Names
IL36B; FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA)
Purity
>95% as determined by SDS-PAGE
Pricing
E Coli IL10 Active Protein – Cat# AAA214314 – Application Data
E Coli IL10 Active Protein – Cat# AAA214314 – Application Data Application Data

IL10, Active Protein (Cat# AAA214314)

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Full Name
Recombinant Mouse IL10
Gene Names
Il10; CSIF; Il-10
Purity
>95% as determined by SDS-PAGE
Pricing
E Coli MCP-2 Active Protein – Cat# AAA214330 – Application Data
E Coli MCP-2 Active Protein – Cat# AAA214330 – Application Data Application Data

MCP-2 (CCL8), Active Protein (Cat# AAA214330)

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Full Name
Recombinant Mouse MCP-2 (CCL8)
Gene Names
Ccl8; HC14; Mcp2; MCP-2; Scya8; AB023418; 1810063B20Rik
Purity
>95% as determined by SDS-PAGE
Pricing

Retinol-binding protein, Active Protein (Cat# AAA78134)

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Full Name
Retinol-binding protein 4 (RBP4) from human plasma,
Gene Names
RBP4; RDCCAS
Purity
Affinity chromatography and size-exclusion chromatography
Pricing

MERS-CoV S-trimer Protein, Active Protein (Cat# AAA177996)

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Full Name
Recombinant MERS-CoV S-trimer Protein (R751S, C-6His)(Active)
Purity
>95% as determined by reducing SDS-PAGE.
Pricing
Human Cells SIRPA/CD172a Active Protein – Cat# AAA177937 – Bioactivity
Human Cells SIRPA/CD172a Active Protein – Cat# AAA177937 – Bioactivity Bioactivity

Signal-Regulatory Protein alpha-1/SIRPA/CD172a) Biotinylated, Active Protein (Cat# AAA177937)

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Full Name
Recombinant Human Signal-Regulatory Protein alpha-1/SIRPA/CD172a (C-6His-Avi) Biotinylated
Gene Names
SIRPA; BIT; MFR; P84; SIRP; MYD-1; SHPS1; CD172A; PTPNS1
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Human Cells 5’-NT/CD73 Active Protein – Cat# AAA177941 – Bioactivity
Human Cells 5’-NT/CD73 Active Protein – Cat# AAA177941 – Bioactivity Bioactivity

5'-Nucleotidase/5'-NT/CD73, Active Protein (Cat# AAA177941)

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Full Name
Recombinant Human 5'-Nucleotidase/5'-NT/CD73 (AAH65937.1, C-Fc)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Human Cells IL-2 Active Protein – Cat# AAA177957 – Bioactivity
Human Cells IL-2 Active Protein – Cat# AAA177957 – Bioactivity Bioactivity

Interleukin-2/IL-2) Biotinylated, Active Protein (Cat# AAA177957)

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Full Name
Recombinant Human Interleukin-2/IL-2 (C-6His-Avi) Biotinylated
Gene Names
IL2; IL-2; TCGF; lymphokine
Purity
>90% as determined by reducing SDS-PAGE
Pricing
Human Cells TROP-2 Active Protein – Cat# AAA177963 – Bioactivity
Human Cells TROP-2 Active Protein – Cat# AAA177963 – Bioactivity Bioactivity

Tumor-associated Calcium Signal Transducer 2/TROP-2 Biotinylated, Active Protein (Cat# AAA177963)

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Full Name
Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-Avi-6His) Biotinylated
Gene Names
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Purity
>95% as determined by reducing SDS-PAGE
Pricing
HEK293 Cells S1 Active Protein – Cat# AAA177983 – Bioactivity
HEK293 Cells S1 Active Protein – Cat# AAA177983 – Bioactivity Bioactivity

SARS-CoV S1 Protein, Active Protein (Cat# AAA177983)

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Full Name
Recombinant SARS-CoV S1 Protein (mFc Tag)(Active)
Purity
>90% as determined by SDS-PAGE
Pricing
Human Cells IL-4 Active Protein – Cat# AAA176986 – Application Data
Human Cells IL-4 Active Protein – Cat# AAA176986 – Application Data Application Data

Interleukin-4/IL-4, Active Protein (Cat# AAA176986)

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Full Name
Recombinant Human Interleukin-4/IL-4 Protein (Active)
Applications
Immunogen
Purity
> 95 % as determined by SDS-PAGE.
Pricing
HEK293 Cells DLL1 Active Protein – Cat# AAA258260 – Application Data
HEK293 Cells DLL1 Active Protein – Cat# AAA258260 – Application Data Application Data (Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-10 ug/mL in the presence of 500 ng/mL recombinant human BMP2.)

DLL1, Active Protein (Cat# AAA258260)

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Full Name
DLL1 Protein, Rat, Recombinant (His Tag)
Purity
>65% as determined by SDS-PAGE
Pricing
HEK293 Cells TIGIT Active Protein – Cat# AAA257951 – Application Data
HEK293 Cells TIGIT Active Protein – Cat# AAA257951 – Application Data Application Data (Measured by its binding ability in a functional ELISA. Immobilized human CD155a-His at 10ug/mL (100uL/well) can bind human TIGIT-Fc, the EC50 of human TIGIT-Fc is 0.03-0.2ug/mL.)

TIGIT, Active Protein (Cat# AAA257951)

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Full Name
TIGIT Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
TIGIT; VSIG9; VSTM3; WUCAM
Purity
>95% as determined by SDS-PAGE
Pricing
293F Cell CTSD Active Protein – Cat# AAA161838 – Bioactivity
293F Cell CTSD Active Protein – Cat# AAA161838 – Bioactivity Bioactivity (Cathepsin D is a lysosomal aspartic protease of the pepsin family. Human cathepsin D is synthesized as a precursor protein, consisting of a signal peptide (residues 118), a propeptide (residues 1964), and a mature chain (residues 65412). The mature chain can be processed further to the light (residues 65161) and heavy (residues 169412) chains. It is expressed in most cells and overexpressed in breast cancer cells. It is a major enzyme in protein degradation in lysosomes, and also involved in the presentation of antigenic peptides. Mice deficient in this enzyme showed a progressive atrophy of the intestinal mucosa, a massive destruction of lymphoid organs, and a profound neuronal ceroid lipofucinosis, indicating that cathepsin D is essential for proteolysis of proteins regulating cell growth and tissue homeostasis. The activity of recombinant human CTSD is measured by its ability to cleave a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 0.1 M NaOAc, 0.2 M NaCl, pH 3.5. The rhCTSD is diluted to 20 ug/ml in assay buffer, then incubated at 37 degree C for 30min. The incubated rhCTSD is diluted to 5 ug/mL in assay buffer. Loading into a black well plate 50 uL of 5 ug/mL rhCTSD and start the reaction by adding 50 uL of 60 uM substrate, with a substrate blank containing 50 uL assay buffer, 50 uL substrate, and no rhCTSD. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The specific activity of recombinant human CTSD is > 675 pmol/min/ug.)

Cathepsin D (CTSD), Active Protein (Cat# AAA161838)

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Full Name
Active Cathepsin D (CTSD)
Gene Names
CTSD; CPSD; CLN10
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Rabbit (Rabbit Erythrocytes) HB Active Protein – Cat# AAA161850 – Bioactivity
Rabbit (Rabbit Erythrocytes) HB Active Protein – Cat# AAA161850 – Bioactivity Bioactivity (Hemoglobin (HB) is a protein in red blood cells which contains iron. It is used to transport oxygen around the human body. Hemoglobin is found in the red blood cells of almost all vertebrates. Hemoglobin has peroxidase activity. In the presence of hydrogen peroxide, hemoglobin can catalyze the substrates 3,3 ', 5,5' - tetramethylbenzidine (TMB) to produce a blue compound which has a maximum absorption at 595 nm. Thus, the activity of native rabbit hemoglobin was measured by its ability to catalyze the substrates of TMB. The reaction was performed in PBS, pH 7.4 (Assay Buffer), ainitiated by addition 40 uL of various concentrations of HB (diluted by Assay Buffer) to 160 uL of TMB. Incubated at 37 degree C for 20min, then read at a wavelength of 595 nm immediately. The result was shown in figure 1, and the OD value was in a linear relationship with the concentration of HB.)

Hemoglobin (HB), Active Protein (Cat# AAA161850)

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Full Name
Active Hemoglobin (HB)
Gene Names
HBA; HBA1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli FABP4 Active Protein – Cat# AAA161857 – Bioactivity
E Coli FABP4 Active Protein – Cat# AAA161857 – Bioactivity Bioactivity (Fatty acid binding protein-4 (FABP4) is a member of a large superfamily of lipid binding proteins that are expressed in a tissue specific manner. FABP4 is one of ten cytoplasmic FABPs that are 14-15 kDa in size and range from 126-140 amino acids (aa) in length. Although all are highly conserved in their tertiary structure, there is only modest aa identity between any two members. Lipase, Hormone Sensitive (LIPE) has been identified as an interactor of FABP4, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse FABP4 and recombinant human LIPE. Briefly, FABP4 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to LIPE-coated microtiter wells and incubated for 1h at 37 degree C. Wells were aspirated and incubated for 1h with anti-FABP4 mAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450 nm immediately. The binding activity of FABP4 and LIPE was shown in Figure 1, and this effect was in a dose dependent manner. The EC50 for this effect is 0.23 ug/mL.)

Fatty Acid Binding Protein 4 (FABP4), Active Protein (Cat# AAA161857)

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Full Name
Active Fatty Acid Binding Protein 4 (FABP4)
Gene Names
Fabp4; Ap2; Lbpl; 422/aP2; ALBP/Ap2
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
293F Cell CD19 Active Protein – Cat# AAA161866 – Bioactivity
293F Cell CD19 Active Protein – Cat# AAA161866 – Bioactivity Bioactivity (Cluster Of Differentiation 19 (CD19) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed in normal and neoplastic B cells, and it modulates the threshold of B cell activation for amplifying B cell receptor signaling. This protein has recently emerged as a very attractive biomarker and therapeutic target for B-cell malignancies. The development of safe and effective ligands for CD19 has become an important need for the development of targeted conventional and immunotherapies. As far as we know, signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human CD19 and recombinant human VAV1. Briefly, biotin-linked CD19 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to VAV1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of recombinant human CD19 and recombinant human VAV1 was shown in Figure 1, the EC50 for this effect is 0.67 ug/mL.)

Cluster Of Differentiation 19 (CD19), Active Protein (Cat# AAA161866)

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Full Name
Active Cluster Of Differentiation 19 (CD19)
Gene Names
CD19; B4; CVID3
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli MET Active Protein – Cat# AAA161879 – Bioactivity
E Coli MET Active Protein – Cat# AAA161879 – Bioactivity Bioactivity (c-Met is a receptor tyrosine kinase belonging to the MET (MNNG HOS transforming gene) family, and is expressed on the surfaces of various cells. Hepatocyte growth factor (HGF) is the ligand for this receptor. The binding of HGF to c-Met initiates a series of intracellular signals that mediate embryogenesis and wound healing in normal cells. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human MET and recombinant human HGF. Briefly, MET was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to HGF-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-MET pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human MET and recombinant human HGF was shown in Figure 1, the EC50 for this effect is 0.02 ug/mL.)

C-Met (MET), Active Protein (Cat# AAA161879)

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Full Name
Active C-Met (MET)
Gene Names
MET; HGFR; AUTS9; RCCP2; c-Met
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
E Coli TGFBR2 Active Protein – Cat# AAA161898 – Bioactivity
E Coli TGFBR2 Active Protein – Cat# AAA161898 – Bioactivity Bioactivity (Transforming growth factor beta receptor 2 (TGFBR2) is a tumor suppressor gene that plays a role in the differentiation of striated cells and remodeling of coronary arteries. Single nucleotide polymorphisms (SNPs) of this gene are associated with Marfan syndrome and sudden death in patients with coronary artery disease. Cardiovascular remodeling and T cell activation of TGFBR2 gene suggest that the TGFBR2 gene SNPs are related to the pathogenesis of Kawasaki disease (KD) and coronary artery lesion (CAL). Endoglin can regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. A functional ELISA assay was conducted to detect the interaction of recombinant human TGFBR2 and recombinant rat Endoglin (ENG). Briefly, TGFBR2 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to ENG-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-TGFBR2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630nm immediately. The binding activity of recombinant human TGFBR2 and recombinant rat ENG was shown in Figure 1, the EC50 for this effect is 36.1 ng/mL.)

Transforming Growth Factor Beta Receptor II (TGFbR2), Active Protein (Cat# AAA161898)

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Full Name
Active Transforming Growth Factor Beta Receptor II (TGFbR2)
Gene Names
TGFBR2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
E Coli GSTM1 Active Protein – Cat# AAA161759 – Bioactivity
E Coli GSTM1 Active Protein – Cat# AAA161759 – Bioactivity Bioactivity (Glutathione S-Transferases (GSTs) are members of the phase II detoxification enzyme family that conjugate glutathione to various electrophilic compounds, including metabolites generated by oxidative processes in the body, environmental toxins or carcinogens, and anti-cancer drugs. GSTM1 is a cytosolic protein that belongs to the mu class of the GST superfamily. GSTM1 catalyze the endogenous glutathione conjugation 1-Chloro-2,4-dinitrobenzene (CDNB), which can increase in the absorbance at 340 nm. The reaction was performed in adding 10 ul 200 mM glutathione (reduced) and 10 ul 100 mM CDNB in 980 ul 100 mM NaH2PO4 (pH7.0), rapidly mixed. Then add 50 ul mixed substrates to 50 ul different concentrations of recombinant chicken GSTM1, mix gently. Incubated at 37 degree C for 5min, then read at a wavelength of 340 nm. The specific activity of recombinant chicken GSTM1 is >2500 pmol/min/ug.)

Glutathione S Transferase Mu 1 (GSTM1), Active Protein (Cat# AAA161759)

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Full Name
Active Glutathione S Transferase Mu 1 (GSTM1)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
E Coli GSTA3 Active Protein – Cat# AAA161767 – Bioactivity
E Coli GSTA3 Active Protein – Cat# AAA161767 – Bioactivity Bioactivity (GSTa3 (Glutathione S-transferase a3) is an enzyme that plays an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. This subfamily of enzymes has a particular role in protecting cells from Reactive Oxygen Species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. GSTa3 catalyze the endogenous glutathione conjugation 1-Chloro-2,4-dinitrobenzene (CDNB), which can increase in the absorbance at 340 nm. The reaction was performed in adding 10 ul 200 mM glutathione (reduced) and 10 ul 100 mM CDNB in 980 ul 100 mM NaH2PO4 (pH7.0), rapidly mixed. Then add 50 ul mixed substrates to 50 ul different concentrations of recombinant mouse GSTa3, mix gently. Incubated at 37 degree C for 5min, then read at a wavelength of 340 nm. The specific activity of recombinant mouse GSTa3 is >60,000 pmol/min/ug.)

Glutathione S Transferase Alpha 3 (GSTa3), Active Protein (Cat# AAA161767)

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Full Name
Active Glutathione S Transferase Alpha 3 (GSTa3)
Gene Names
Gsta3; Gst2-3
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli CRP Active Protein – Cat# AAA161783 – Bioactivity
E Coli CRP Active Protein – Cat# AAA161783 – Bioactivity Bioactivity (Reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose levels rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via C1q. Besides, Coagulation Factor II (F2) has been identified as an interactor of CRP, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse CRP and recombinant rat F2. Briefly, CRP was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to F2-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-CRP pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant mouse CRP and recombinant rat F2 was shown in Figure 1, the EC50 for this effect is 0.02 ug/mL.)

C ReProtein (CRP), Active Protein (Cat# AAA161783)

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Full Name
Active C Reactive Protein (CRP)
Gene Names
Crp; AI255847
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli RBP4 Active Protein – Cat# AAA161805 – Bioactivity
E Coli RBP4 Active Protein – Cat# AAA161805 – Bioactivity Bioactivity (Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a beta-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). The activity of recombinant human RBP4 was measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4. RBP4 was diluted to 50 ug/ml in 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, pH 7.5 (assay buffer) and the retinoic acid was diluted to 100, 30, 10, 3 and 1 uM in 95% ethanol. Mixing 112.5 uL of 50 ug/mL rhRBP4 and 12.5 uL of retinoic acid serial dilutions in microtubes and a blank containing 112.5 uL of 50 ug/mL rhRBP4 and 12.5 uL of 95% ethanol, then incubate at room temperature for 30 minutes. Loading 100 ul of the reaction mixtures and blank and read at excitation and emission wavelengths of 280 nm and 340 nm (top read), respectively, in endpoint mode. The result was shown in figure 1, the 50% binding concentration (BC50) is >30 uM.)

Retinol Binding Protein 4 (RBP4), Active Protein (Cat# AAA161805)

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Full Name
Active Retinol Binding Protein 4 (RBP4)
Gene Names
RBP4; RDCCAS
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli RBP4 Active Protein – Cat# AAA161808 – Bioactivity
E Coli RBP4 Active Protein – Cat# AAA161808 – Bioactivity Bioactivity (Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a beta-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). The activity of recombinant rat RBP4 was measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4. RBP4 was diluted to 50 ug/ml in 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, pH 7.5 (assay buffer) and the retinoic acid was diluted to 800, 400, 200, 100, 30, 10, 3, 1, 0.5 and 0.1 uM in 95% ethanol. Mixing 112.5 uL of 50 ug/mL rrRBP4 and 12.5 uL of retinoic acid serial dilutions in microtubes and a blank containing 112.5 uL of 50 ug/mL rrRBP4 and 12.5 uL of 95% ethanol, then incubate at room temperature for 30 minutes. Loading 100 ul of the reaction mixtures and blank and read at excitation and emission wavelengths of 280 nm and 340 nm (top read), respectively, in endpoint mode. The result was shown in figure 1, the 50% binding concentration (BC50) is >22 uM.)

Retinol Binding Protein 4 (RBP4), Active Protein (Cat# AAA161808)

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Full Name
Active Retinol Binding Protein 4 (RBP4)
Gene Names
Rbp4; RBPA
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
E Coli GPC3 Active Protein – Cat# AAA161815 – Bioactivity
E Coli GPC3 Active Protein – Cat# AAA161815 – Bioactivity Bioactivity (Glypican-3 (GPC3), a 70 kDa protein, is a member of the glypican family that attaches to the cell surface by a glycosylphosphatidylinositol anchor, is specifically up-regulated in hepatocellular carcinoma (HCC) although rarely or not expressed in normal liver tissues, making it a perfect test and treatment target for HCC. GPC3 is also a negative transcriptional regulator and tumor suppressor that inhibits the growth of breast, ovary, and lung cancer cells. It is reported that GPC3 can form a complex with insulin-like growth factor 2 (IGF2), and might thereby modulate IGF2 action. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse GPC3 and recombinant rat IGF2. Briefly, GPC3 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to IGF2-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-GPC3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant mouse GPC3 and recombinant rat IGF2 was shown in Figure 1, the EC50 for this effect is 0.12 ug/mL.)

Glypican 3 (GPC3), Active Protein (Cat# AAA161815)

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Full Name
Active Glypican 3 (GPC3)
Gene Names
Gpc3; OCI-5
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli NMT1 Active Protein – Cat# AAA161922 – Bioactivity
E Coli NMT1 Active Protein – Cat# AAA161922 – Bioactivity Bioactivity (N-Myristoyltransferase 1 (NMT1) is an indispensable eukaryotic enzyme that belongs to the NMT family. NMT1 can catalyses the transfer of myristoyl groups to the amino acid terminal residues of numerous proteins. This catalytic process is required for the growth and development of many eukaryotes and viruses. Furthermore, it is recognized that N-myristoylation can also occur posttranslationally on an internal glycine exposed by caspase cleavage during apoptosis. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human NMT1 and recombinant human CASP3. Briefly, biotin-linked NMT1 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to CASP3-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of recombinant human NMT1 and recombinant human CASP3 was shown in Figure 1, the EC50 for this effect is 0.01 ug/mL.)

N-Myristoyltransferase 1 (NMT1), Active Protein (Cat# AAA161922)

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Full Name
Active N-Myristoyltransferase 1 (NMT1)
Gene Names
NMT1; NMT
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
E Coli IFNG Active Protein – Cat# AAA161669 – Bioactivity
E Coli IFNG Active Protein – Cat# AAA161669 – Bioactivity Bioactivity (IFN-g is a dimerized soluble cytokine that is the only member of the type II class of interferons. The importance of IFNg in the immune system stems in part from its ability to inhibit viral replication directly and most importantly from its immunostimulatory and immunomodulatory effects. Studies show that IFN-gamma can rapidly regulate STAT activation by IL-10 and alters macrophage responses to IL-10. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant pig IFN-g and recombinant pig IL-10. Briefly, IFN-g was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to IL-10-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-IFN-g pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant pig IFN-g and recombinant pig IL-10 was shown in Figure 1, the EC50 for this effect is 3.1 ug/mL.)

Interferon Gamma (IFNg), Active Protein (Cat# AAA161669)

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Full Name
Active Interferon Gamma (IFNg)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.


All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Learn more in our guide “How active proteins work”.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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