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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 750-800 of 2875 product results


product-image-AAA149228_SDS_PAGE13.jpg SDS-PAGE

Tissue Inhibitors Of Metalloproteinase 3 (TIMP3), Active Protein (Cat# AAA149228)

No reviews yet
Full Name
Active Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
Gene Names
Timp3; Timp-3
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA152954_BIOACTIVITY11.jpg Bioactivity (Figure 2. Inhibition of A549 cells proliferation after stimulated with recombinant pig IFN-alpha.)

Interferon Alpha (IFNa), Active Protein (Cat# AAA152954)

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Full Name
Active Interferon Alpha (IFNa)
Gene Names
IFNA1; IFN1@; IFN-ALPHA-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA152978_BIOACTIVITY13.jpg Bioactivity (MMP2 is a zinc-dependent enzymes capable of cleaving components of the extracellular matrix, which belongs to the matrix metalloproteinase (MMP) family .It is a gelatinase A, 72 kDa type IV collagenase which can hydrolyze gelatin under certain conditions.)

Matrix Metalloproteinase 2 (MMP2), Active Protein (Cat# AAA152978)

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Full Name
Active Matrix Metalloproteinase 2 (MMP2)
Gene Names
MMP2; CLG4; MONA; CLG4A; TBE-1; MMP-II
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing

Interleukin-7 (IL7), Active Protein (Cat# AAA235615)

No reviews yet
Full Name
Recombinant Human Interleukin-7 (IL7)
Gene Names
IL7; IL-7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA214312_AD13.png Application Data

IL1A, Active Protein (Cat# AAA214312)

No reviews yet
Full Name
Recombinant Mouse IL1A
Gene Names
Il1a; Il-1a
Purity
>95% as determined by SDS-PAGE
Pricing

HSV2 gG2, Active Protein (Cat# AAA75436)

No reviews yet
Full Name
HSV2 gG2 protein
Applications
Western Blot
Purity
> 95% pure
Pricing

IFN Type 1, Active Protein (Cat# AAA75446)

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Full Name
IFN Type 1 protein
Purity
> 95% pure
Pricing

Rheumatoid Factor (RF), Active Protein (Cat# AAA44876)

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Full Name
Rheumatoid Factor (RF) Concentrate - > 5 kIU/mL
Purity
Purified
product-image-AAA150332_WB10.jpg WB (Western Blot) (Western BlotSample: Recombinant FGF18, Human;Antibody: Rabbit Anti- Human FGF18 Ab)

Fibroblast Growth Factor 18 (FGF18), Active Protein (Cat# AAA150332)

No reviews yet
Full Name
Active Fibroblast Growth Factor 18 (FGF18)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing

Peroxiredoxin-3, Active Protein (Cat# AAA38770)

No reviews yet
Full Name
Recombinant Human Peroxiredoxin-3
Gene Names
PRDX3; AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Salmonella Typhimurium Uridine phosphorylase, Active Protein (Cat# AAA38288)

No reviews yet
Full Name
Recombinant Salmonella Typhimurium Uridine phosphorylase
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
product-image-AAA48381_BIOACTIVITY13.jpg Bioactivity (Human IgM is coated at 2 ug/ml (100 ul/well) can bind Human pIgR. The ED50 range )

pIgR, Active Protein (Cat# AAA48381)

No reviews yet
Full Name
Recombinant human pIgR protein
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
product-image-AAA48400_BIOACTIVITY13.jpg Bioactivity (Mouse IL-5 in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range )

IL-5, Active Protein (Cat# AAA48400)

No reviews yet
Full Name
Recombinant mouse IL-5 protein
Gene Names
Il5; Il-5
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
product-image-AAA48623_SDS_PAGE15.jpg SDS-PAGE

DLD, Active Protein (Cat# AAA48623)

No reviews yet
Full Name
DLD, 36-509aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
DLD; E3; LAD; DLDD; DLDH; GCSL; PHE3
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

Ephrin-A5, Active Protein (Cat# AAA48998)

No reviews yet
Full Name
Recombinant human Ephrin-A5 protein
Gene Names
EFNA5; AF1; EFL5; RAGS; EPLG7; GLC1M; LERK7
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

Endostatin, Active Protein (Cat# AAA79266)

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Full Name
Human Endostatin
Gene Names
COL18A1; KS; KNO; KNO1
Reactivity
Human
Purity
98 % (SDS-PAGE, HPLC)
Pricing

Factor X, Active Protein (Cat# AAA75328)

No reviews yet
Full Name
Factor X protein
Gene Names
F10; fX; Cf10
Purity
> 98%
Pricing

COVID 19 Spike Protein (S) D614G Coronavirus, Active Protein (Cat# AAA243741)

No reviews yet
Full Name
Recombinant Human Novel Coronavirus Spike glycoprotein(S) (D614G), partial (Active)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA214336_AD13.png Application Data

CNTF, Active Protein (Cat# AAA214336)

No reviews yet
Full Name
Recombinant Rat CNTF
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA79147_AD13.jpg Application Data

PlGF, Active Protein (Cat# AAA79147)

No reviews yet
Full Name
Rat PlGF
Gene Names
Pgf; Plgf
Reactivity
Rat
Purity
> 95% by SDS-PAGE & silver stain
Pricing

MIG, Active Protein (Cat# AAA38091)

No reviews yet
Full Name
Recombinant Human MIG (CXCL9)
Gene Names
CXCL9; CMK; MIG; Humig; SCYB9; crg-10
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor receptor-2 Fc Chimera, Active Protein (Cat# AAA38400)

No reviews yet
Full Name
Recombinant Human Vascular Endothelial Growth Factor receptor-2 Fc Chimera
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
product-image-AAA161727_BIOACTIVITY13.jpg Bioactivity (Complement Component 5a (C5a) is a component of the complement system which plays a key role in promoting migration and adherence of neutrophils and monocytes to vessel walls. The activity of recombinant human C5a was also measured by its ability to induce N-acetyl-beta-D-glucosaminidase release from differentiated U937 human histiocytic lymphoma cells. 3.2*106 differentiated U937 cells were added to the 24-well plate and different concentrations of rhC5a was added to the 24-well plate and incubated at 37 degree C for 3min. The cells were centrifuged at 400 g for 3min, and the supernatant contained N-acetyl-beta-D-glucosaminidase. The enzyme activity of N-acetyl-beta-D-glucosaminidase was measured by the substrate of 4-Nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside. The result was shown in figure 1, It was obvious that rhC5a can significantly induce N-acetyl-beta-D-glucosaminidase release.)

Complement Component 5a (C5a), Active Protein (Cat# AAA161727)

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Full Name
Active Complement Component 5a (C5a)
Gene Names
Hc; C5; He; C5a
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing

Prolactin, Active Protein (Cat# AAA38156)

No reviews yet
Full Name
Recombinant Mouse Prolactin
Gene Names
Prl; Prl1a1; AV290867
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Matrix Metalloproteinase-8, Active Protein (Cat# AAA38265)

No reviews yet
Full Name
Recombinant Human Matrix Metalloproteinase-8
Gene Names
MMP8; HNC; CLG1; MMP-8; PMNL-CL
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing
product-image-AAA79214_AD13.jpg Application Data

GM-CSF, Active Protein (Cat# AAA79214)

No reviews yet
Full Name
Human GM-CSF
Gene Names
CSF2; GMCSF
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA48356_BIOACTIVITY13.jpg Bioactivity (Porcine GM-CSF stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ? 40 ng/ml.)

GM-CSF, Active Protein (Cat# AAA48356)

No reviews yet
Full Name
Recombinant Porcine GM-CSF protein
Gene Names
CSF2; GM-CSF
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS - PAGE
Pricing
product-image-AAA48387_BIOACTIVITY13.jpg Bioactivity (Human Proinsulin in a cell proliferation assay using MCF7 human breast cancer cell. The ED50 range )

NRG1/HRG1, Active Protein (Cat# AAA48387)

No reviews yet
Full Name
Recombinant human NRG1/HRG1 protein
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
product-image-AAA161697_BIOACTIVITY13.jpg Bioactivity (Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes. TIMP-2 also has erythroidpotentiating and cell growth promoting activities. The activity of recombinant human TIMP2 was measured by its ability to inhibit rhMMP2 cleavage of a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. rhMMP2 was diluted to 100 ug/ml and activated with 1 mM APMA at 37 degree C for 1 hour and rhTIMP2 (MW: 51.75 KD) was diluted to different concentrations with the assay buffer. Mix 8 ul of rhTIMP2 curve dilutions, 12.8 ul of activated rhMMP-2, and 59.2 ul of assay buffer, including a control containing assay buffer and the diluted rhMMP-2 and incubate the reactions for 2 hours at 37 degree C. Loading 50 ul of the incubated mixtures which were diluted five-fold in assay buffer into empty wells of a plate, and start the reaction by adding 50 ul of 20 uM substrate. Include a substrate blank containing 50 ul of assay buffer and 50 ul of 20 uM substrate. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The result was shown in Figure 1 and it was obvious that recombinant human TIMP2 significantly decreased rhMMP2 activity. The inhibition IC50 was )

Tissue Inhibitors Of Metalloproteinase 2 (TIMP2), Active Protein (Cat# AAA161697)

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Full Name
Active Tissue Inhibitors Of Metalloproteinase 2 (TIMP2)
Gene Names
TIMP2; DDC8; CSC-21K
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing

Myeloid cell surface antigen CD33 (CD33), Active Protein (Cat# AAA114015)

No reviews yet
Full Name
Recombinant Human Myeloid cell surface antigen CD33 (CD33), partial
Gene Names
CD33; p67; SIGLEC3; SIGLEC-3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing

Beta-Nerve Growth Factor (NGF), Active Protein (Cat# AAA235613)

No reviews yet
Full Name
Recombinant Human Beta-nerve growth factor (NGF) (Active)
Gene Names
NGF; NGFB; HSAN5; Beta-NGF
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA258173_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized Mouse Ephrin B2 His at 2 ug/ml (100 ul/well) can bind Mouse EphB4 hFc, the EC50 of Mouse EphB4 hFc is 2.0-10.0 ng/mL.)

EphB4, Active Protein (Cat# AAA258173)

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Full Name
EphB4 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Ephb4; Htk; MDK2; Myk1; Tyro11; AI042935; b2b2412Clo
Purity
>97% as determined by SDS-PAGE
Pricing
product-image-AAA153133_BIOACTIVITY11.jpg Bioactivity (One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant human CES3 is 700 pmol/min/ug.)

Carboxylesterase 3 (CES3), Active Protein (Cat# AAA153133)

No reviews yet
Full Name
Active Carboxylesterase 3 (CES3)
Gene Names
CES3; ES31
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153141_BIOACTIVITY13.jpg Bioactivity (PNGase F (Peptide-N-glycosidase F) is a kind of enzymes for the deglycosylation of glycoproteins. The enzyme releases asparagine-linked oligosaccharides from glycoproteins and glycopeptides by hydrolyzing the amide of the asparagine (Asn) side chain. Thus)

Peptide-N4-N-Acetyl-Beta-D-Glucosaminyl Asparagine Amidase F (PNGaseF), Active Protein (Cat# AAA153141)

No reviews yet
Full Name
Active Peptide-N4-N-Acetyl-Beta-D-Glucosaminyl Asparagine Amidase F (PNGaseF)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing

Insulin Like Growth Factor-1, Active Protein (Cat# AAA38145)

No reviews yet
Full Name
Recombinant Rat Insulin Like Growth Factor-1
Purity
Greater than 98.0% as determined by SDS-PAGE.
Pricing
product-image-AAA79263_AD13.jpg Application Data

VEGF121, Active Protein (Cat# AAA79263)

No reviews yet
Full Name
Human VEGF121
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
product-image-AAA79274_AD11.jpg Application Data (In vitro: The proliferative response to recombinant rat VEGF-CC152S was assayed in VEGFR3-expressing porcine aortic endothelial (PAE) cells. Briefly, cells were plated in 12-well plates and incubated in DMEM medium supplemented with 1% fetal calf serum for cell cycle arrest 24h prior to stimulation of cell proliferation with recombinant VEGF-CC152S at the concentrations of 50 and 100 ng/mL. After 48h in culture, the cell proliferative response was assayed (WST-1 colorimetric assay), and the results expressed as % of control non-stimulated cells (mean + sem).)

VEGF-C152S, Active Protein (Cat# AAA79274)

No reviews yet
Full Name
Rat VEGF-C152S
Reactivity
Rat
Purity
> 90% by SDS-PAGE & silver stain
Pricing
product-image-AAA76380_AD13.jpg Application Data (SARS COV-2 Spike S RBD-human Fc HPLCThe purity of 2019-nCoV Spike RBD Fc is greater than 95% as determined by SEC-HPLC.)

2019 nCoV/COVID19 RBD, Active Protein (Cat# AAA76380)

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Full Name
2019 nCoV/COVID19 RBD Recombinant-hFc
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing

BCA1, Active Protein (Cat# AAA75198)

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Full Name
BCA1 protein
Gene Names
CA1; ARABIDOPSIS THALIANA SALICYLIC ACID-BINDING PROTEIN 3; ATBCA1; ATSABP3; BETA CARBONIC ANHYDRASE 1; CA1; carbonic anhydrase 1; F4P13.5; F4P13_5; SABP3; SALICYLIC ACID-BINDING PROTEIN 3
Purity
> 98% pure
Pricing
product-image-AAA161681_BIOACTIVITY13.jpg Bioactivity (Leptin is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Many of leptin's effects are mediated through neuropeptide-containing neurons and neuropeptide receptors in the hypothalamus. Although regulation of fat stores is deemed to be the primary function of leptin, it also plays a role in other physiological processes, as evidenced by its multiple sites of synthesis other than fat cells, and the multiple cell types beside hypothalamic cells that have leptin receptors. A functional binding ELISA assay was conducted to detect the interaction of recombinant mouse LEP and recombinant human LEPR. Briefly, LEP were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to LEPR-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-LEP pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450 nm immediately. The binding activity of of LEP and LEPR was shown in Figure 1, the EC50 for this effect is 0.26 ug/mL.)

Leptin (LEP), Active Protein (Cat# AAA161681)

No reviews yet
Full Name
Active Leptin (LEP)
Gene Names
Lep; ob; obese
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA257876_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized TGFBR2h (1-166Q) at 10 ug/mL (100 uL/well) can bind TGFB1-His/Biotin, the EC50 of human TGFB1-His/Biotin is 0.50-1.20 ug/mL.)

TGFBR2, Active Protein (Cat# AAA257876)

No reviews yet
Full Name
TGFBR2 Protein, Human, Recombinant (ECD, His Tag)
Gene Names
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Purity
>90% as determined by SDS-PAGE
Pricing

Cystatin C, Active Protein (Cat# AAA78138)

No reviews yet
Full Name
Recombinant human cystatin C
Gene Names
CST3; ARMD11
Purity
Chromatography
Pricing

BD2, Active Protein (Cat# AAA75442)

No reviews yet
Full Name
BD2 protein
Gene Names
DEFB4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102
Purity
> 98% pure
Pricing

Brain-Derived Neurotrophic Factor, Active Protein (Cat# AAA38107)

No reviews yet
Full Name
Recombinant Human Brain-Derived Neurotrophic Factor
Gene Names
BDNF; ANON2; BULN2
Purity
BDNF is greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Morphogenetic protein-2, Active Protein (Cat# AAA38138)

No reviews yet
Full Name
Recombinant Human Bone Morphogenetic protein-2
Gene Names
BMP2; BDA2; BMP2A
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-1 beta, Active Protein (Cat# AAA38142)

No reviews yet
Full Name
Recombinant Mouse Interleukin-1 beta
Gene Names
Il1b; Il-1b; IL-1beta
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
product-image-AAA148204_AD10.jpg Application Data

Fibroblast Growth Factor 22 (FGF22), Active Protein (Cat# AAA148204)

No reviews yet
Full Name
Active Fibroblast Growth Factor 22 (FGF22)
Gene Names
Fgf22; FGF-22; 2210414E06Rik
Reactivity
Mouse
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA161790_BIOACTIVITY13.jpg Bioactivity (PRL (prolactin), also known as luteotropin, is a hormone secreted from the pituitary gland and is best known for its role in enabling mammals to produce milk. PRL plays an essential role in metabolism, regulation of the immune system through activating its specific membrane-anchored receptor (PRLR). PRL can bind to PRLR, inducing JAK2 association that leads to downstream activation of multiple pathways that include STAT3, STAT5, PI3K, AKT, and ERK. A functional binding ELISA assay was conducted to detect the interaction of recombinant zebrafish PRL and recombinant rat JAK2. Briefly, PRL was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to JAK2 -coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PRL pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant zebrafish PRL and recombinant rat JAK2 was shown in Figure 1, the EC50 for this effect is 0.95 ug/mL.)

Prolactin (PRL), Active Protein (Cat# AAA161790)

No reviews yet
Full Name
Active Prolactin (PRL)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing

IL-17A, Active Protein (Cat# AAA79205)

No reviews yet
Full Name
Human IL-17A
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
product-image-AAA48579_SDS_PAGE15.jpg SDS-PAGE (3ug by SDS-Page under reducing condition and visualized by coomassie blue stain.)

FKBP3, Active Protein (Cat# AAA48579)

No reviews yet
Full Name
FKBP3, 1-224aa, Human, E Coli (Bioactivity Validated)
Gene Names
FKBP3; FKBP-3; FKBP25; PPIase; FKBP-25
Applications
SDS-PAGE, Enzyme Activity
Purity
> 90% by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.


All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Learn more in our guide “How active proteins work”.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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