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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 600-650 of 2567 product results


Bone Morphogenetic protein-13, Active Protein (Cat# AAA38030)

No reviews yet
Full Name
Recombinant Human Bone Morphogenetic protein-13
Gene Names
GDF6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; LCA17; MCOP4; SCDO4; BMP-13; MCOPCB6
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interferon-alpha 2c, Active Protein (Cat# AAA38061)

No reviews yet
Full Name
Recombinant Human Interferon-alpha 2c
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
>97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

Epithelial Neutrophil-Activating Protein 78, Active Protein (Cat# AAA38090)

No reviews yet
Full Name
Recombinant Human Epithelial Neutrophil-Activating Protein 78 (CXCL5)
Gene Names
CXCL5; SCYB5; ENA-78
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Creatine Kinase Brain, Active Protein (Cat# AAA38098)

No reviews yet
Full Name
Recombinant Human Creatine Kinase Brain
Gene Names
CKB; BCK; B-CK; CKBB; HEL-211; HEL-S-29
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Salmonella Typhimurium Uridine phosphorylase, Active Protein (Cat# AAA38288)

No reviews yet
Full Name
Recombinant Salmonella Typhimurium Uridine phosphorylase
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Creatine Kinase, Active Protein (Cat# AAA44789)

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Full Name
Creatine Kinase (CPK/CK), Bovine Heart
Gene Names
ckb; tck1
Purity
Purified
Pricing

Kallikrein, Active Protein (Cat# AAA44797)

No reviews yet
Full Name
Kallikrein, Porcine Pancreas
Purity
Purified
Pricing

Lactate Dehydrogenase, Active Protein (Cat# AAA44807)

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Full Name
Lactate Dehydrogenase (LDH), Bovine Heart
Purity
Purified
Pricing

Pyruvate Kinase, Active Protein (Cat# AAA44819)

No reviews yet
Full Name
Pyruvate Kinase (PK), Rabbit Muscle
Pricing

Luteinizing Hormone, Active Protein (Cat# AAA44840)

No reviews yet
Full Name
Luteinizing Hormone (LH), Human Pituitary Gland
Purity
>= 98% (SDS-PAGE)

Peroxiredoxin-3, Active Protein (Cat# AAA38770)

No reviews yet
Full Name
Recombinant Human Peroxiredoxin-3
Gene Names
PRDX3; AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Bleomycin Hydrolase, Active Protein (Cat# AAA38866)

No reviews yet
Full Name
Recombinant Human Bleomycin Hydrolase
Gene Names
BLMH; BH; BMH
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing

Beta Defensin -1, Active Protein (Cat# AAA38586)

No reviews yet
Full Name
Recombinant Human Beta Defensin -1
Gene Names
DEFB1; BD1; HBD1; DEFB-1; DEFB101
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Growth Hormone, Active Protein (Cat# AAA38592)

No reviews yet
Full Name
Recombinant Rabbit Growth Hormone Binding Protein
Purity
Greater than 98.0% as determined bySDS-PAGE.
Pricing

Trefoil Factor-1, Active Protein (Cat# AAA38601)

No reviews yet
Full Name
Recombinant Human Trefoil Factor-1
Gene Names
TFF1; pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Mitogen Activated Kinase Kinase 1, Active Protein (Cat# AAA38618)

No reviews yet
Full Name
Recombinant Human Mitogen Activated Kinase Kinase 1
Gene Names
MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing

LR3 Insulin Like Growth Factor-1, Active Protein (Cat# AAA38973)

No reviews yet
Full Name
Recombinant Human LR3 Insulin Like Growth Factor-1
Purity
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC
(b) Analysis by SDS-PAGE
Pricing

Thyroid Stimulating Hormone, Active Protein (Cat# AAA39027)

No reviews yet
Full Name
Human Thyroid Stimulating Hormone
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
product-image-AAA77051_AD11.jpg Melanin and Catecholamine Synthesis Pathways

Tyrosinase, Active Protein (Cat# AAA77051)

No reviews yet
Full Name
Tyrosinase (human), (recombinant) (His-tag)
Gene Names
TYR; CMM8; OCA1A; OCAIA; SHEP3
Purity
>=85% (SDS-PAGE)
Purified by multi-step chromatography
Pricing

PDGFR alpha, Active Protein (Cat# AAA76058)

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Full Name
Human PDGFR alpha Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA76392_AD13.jpg Application Data (Binding and in vitro activity of murine 18V4F hybridoma antibody.Directly coated chemokines were used here for direct comparisons, however in other experiments CCL3 showed a significantly enhanced signal when biotinylated and coated on streptavidin plates.)

MIP-1 alpha (CCL-3), Active Protein (Cat# AAA76392)

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Full Name
Mouse MIP-1 alpha (CCL-3) Recombinant
Gene Names
Ccl3; Mip1a; Scya3; G0S19-1; AI323804; MIP1-(a); LD78alpha; MIP-1alpha; MIP1-alpha
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing

Mutarotase, Active Protein (Cat# AAA78982)

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Full Name
Recombinant Mutarotase from Pig kidney
Pricing
product-image-AAA79168_AD13.jpg Application Data

RANTES (CCL 5), Active Protein (Cat# AAA79168)

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Full Name
Rat RANTES (CCL 5)
Gene Names
Ccl5; Scya5; Rantes
Reactivity
Rat
Purity
> 98% by SDS-PAGE & silver stain
Pricing

HYALURONIDASE, Active Protein (Cat# AAA50501)

No reviews yet
Full Name
NATIVE BOVINE HYALURONIDASE
Applications
ELISA
Pricing
product-image-AAA153115_BIOACTIVITY13.jpg Bioactivity (Catalase (CAT) is an antioxidant enzyme present in all aerobic organisms. It is known to catalyze H2O2 into water and oxygen in an energy-efficient manner in the cells exposed to environmental stress. As we know, H2O2 and (NH4)2MoO4 can produce a stable y)

Catalase (CAT), Active Protein (Cat# AAA153115)

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Full Name
Active Catalase (CAT)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153119_BIOACTIVITY13.jpg Bioactivity (Fibroblast growth factor 17(FGF17)  is a member of the fibroblast growth factorfamily. FGF family members possess broad mitogenicand cell survival activities and are involved in a varietyof biological processes, including embryonicdevelopment cell growth,)

Fibroblast Growth Factor 17 (FGF17), Active Protein (Cat# AAA153119)

No reviews yet
Full Name
Active Fibroblast Growth Factor 17 (FGF17)
Gene Names
FGF17; HH20; FGF-13; FGF-17
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153137_BIOACTIVITY13.jpg Bioactivity (Fibroblast growth factor 15 is a protein in mouse encoded by the Fgf15 gene. It is a member of the fibroblast growth factor (FGF) family but, like FGF19, FGF21 and FGF23, has endocrine functions. FGF15 subsequently acts on a cell surface receptor complex)

Fibroblast Growth Factor 15 (FGF15), Active Protein (Cat# AAA153137)

No reviews yet
Full Name
Active Fibroblast Growth Factor 15 (FGF15)
Gene Names
Fgf19; Fgf15
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA161885_BIOACTIVITY13.jpg Bioactivity (Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays vital roles in modulating metabolism, immunity and oncogenesis. ATF3 acts as a hub of the cellular adaptive-response network. Multiple extracellular signals, such as endoplasmic reticulum (ER) stress, cytokines, chemokines, and LPS, are connected to ATF3 induction. Proto-oncogene c-Fos can bind to ATF3 to regulate signal transduction, cell proliferation and differentiation. Thus a functional ELISA assay was conducted to detect the interaction of recombinant mouse ATF3 and recombinant human FOS. Briefly, ATF3 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FOS-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-ATF3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630nm immediately. The binding activity of recombinant mouse ATF3 and recombinant human FOS was shown in Figure 1, the EC50 for this effect is 0.13 ug/mL.)

Activating Transcription Factor 3 (ATF3), Active Protein (Cat# AAA161885)

No reviews yet
Full Name
Active Activating Transcription Factor 3 (ATF3)
Gene Names
Atf3; LRG-21
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA161937_BIOACTIVITY13.jpg Bioactivity (The Semaphorin 3A(SEMA3A) which belongs to the semaphorin family can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Semaphorin 3A is secreted protein containing a Sema domain, an immunoglobulin C2-like domain and a basic domain near the carboxyl tail. It can be secreted by neurons and surrounding tissue to guide migrating cells and axons in the developing nervous system. Besides, Neuropilin 1 (NRP1) has been identified as an interactor of SEMA3A, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant rat SEMA3A and recombinant human NRP1. Briefly, SEMA3A were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to NRP1-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-SEMA3A pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of recombinant rat SEMA3A and recombinant human NRP1 was shown in Figure 1, the EC50 for this effect is 1.22 ug/mL.)

Semaphorin 3A (SEMA3A), Active Protein (Cat# AAA161937)

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Full Name
Active Semaphorin 3A (SEMA3A)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA161719_BIOACTIVITY13.jpg Bioactivity (Apolipoprotein C1 (APOC1), also known as Apo-CI; ApoC-I; apo-CIB; apoC-IB, is the smallest size apolipoprotein of all apolipoprotein C family (Mr = 6.6 kDa) and located at position 19q13.32. APOC1 is primarily expressed in the liver and activated when monocytes differentiate into macrophages. It plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. It has anti-inflammatory activity and also can promote the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells. Besides, Apolipoprotein C3 (APOC3) has been identified as an interactor of APOC1, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human APOC1 and recombinant mouse APOC3. Briefly, APOC1 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to APOC3-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-APOC1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human APOC1 and recombinant mouse APOC3 was shown in Figure 1, the EC50 for this effect is 2.19 ug/mL.)

Apolipoprotein C1 (APOC1), Active Protein (Cat# AAA161719)

No reviews yet
Full Name
Active Apolipoprotein C1 (APOC1)
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
product-image-AAA161664_BIOACTIVITY11.jpg Bioactivity (Figure 2. Cell proliferation of M-NFS-60 cells after stimulated with G-CSF.)

Colony Stimulating Factor 3, Granulocyte (GCSF), Active Protein (Cat# AAA161664)

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Full Name
Active Colony Stimulating Factor 3, Granulocyte (GCSF)
Gene Names
CSF3; G-CSF
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing

Insulin Like Growth Factor-1, Active Protein (Cat# AAA38111)

No reviews yet
Full Name
Recombinant Human Insulin Like Growth Factor-1
Gene Names
IGF1; IGFI; IGF-I; IGF1A
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC(b) Analysis by SDS-PAGE.
Pricing

Follistatin, Active Protein (Cat# AAA38122)

No reviews yet
Full Name
Recombinant Human Follistatin
Gene Names
FST; FS
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Morphogenetic protein-2, Active Protein (Cat# AAA38138)

No reviews yet
Full Name
Recombinant Human Bone Morphogenetic protein-2
Gene Names
BMP2; BDA2; BMP2A
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Insulin Like Growth Factor-2, Active Protein (Cat# AAA38141)

No reviews yet
Full Name
Recombinant Human Insulin Like Growth Factor-2
Gene Names
IGF2; IGF-II; PP9974; C11orf43
Purity
Greater than 97.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Keratinocyte Growth Factor-2, Active Protein (Cat# AAA38152)

No reviews yet
Full Name
Recombinant Human Keratinocyte Growth Factor-2
Purity
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Stem Cell Factor, Active Protein (Cat# AAA38157)

No reviews yet
Full Name
Recombinant Rat Stem Cell Factor
Gene Names
Kitlg; Mgf; SCF; Kitl
Purity
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor, Active Protein (Cat# AAA38168)

No reviews yet
Full Name
Recombinant Human Vascular Endothelial Growth Factor (121)
Gene Names
VEGFA; VPF; VEGF; MVCD1
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-13, Active Protein (Cat# AAA38182)

No reviews yet
Full Name
Recombinant Mouse Interleukin-13
Gene Names
Il13; Il-13
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing

BBetacellulin, Active Protein (Cat# AAA38191)

No reviews yet
Full Name
Recombinant Bovine Betacellulin
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Interleukin-8, Active Protein (Cat# AAA38079)

No reviews yet
Full Name
Recombinant Human Interleukin-8 (1-72) (CXCL8)
Gene Names
CXCL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Monocyte Chemotactic Protein-1, Active Protein (Cat# AAA38086)

No reviews yet
Full Name
Recombinant Rat Monocyte Chemotactic Protein-1 (CCL2)
Gene Names
Ccl2; MCP-1; Scya2; Sigje
Purity
Greater than 98.0% as determined by SDS-PAGE.
Pricing

MIG, Active Protein (Cat# AAA38091)

No reviews yet
Full Name
Recombinant Human MIG (CXCL9)
Gene Names
CXCL9; CMK; MIG; Humig; SCYB9; crg-10
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Neurotrophin-1, Active Protein (Cat# AAA38018)

No reviews yet
Full Name
Recombinant Human Neurotrophin-1
Gene Names
CLCF1; CLC; NR6; BSF3; NNT1; BSF-3; CISS2; NNT-1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Granulocyte Macrophage, Active Protein (Cat# AAA38831)

No reviews yet
Full Name
Recombinant Rhesus Macaque Granulocyte Macrophage-Colony Stimulating Factor
Purity
Greater than 95.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Pricing

Flt3-Ligand, Active Protein (Cat# AAA38706)

No reviews yet
Full Name
Recombinant Human Flt3-Ligand, HEK
Gene Names
FLT3LG; FL; FLT3L
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Coagulation Factor IX, Active Protein (Cat# AAA38450)

No reviews yet
Full Name
Human Coagulation Factor IX
Gene Names
F9; FIX; P19; PTC; HEMB; THPH8
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Staphylococcal Protein-A, Active Protein (Cat# AAA38452)

No reviews yet
Full Name
Recombinant Staphylococcal Protein-A
Purity
Greater than 95.0% as determined by RP-HPLC.
Pricing

MHC class I chain-related gene A, Active Protein (Cat# AAA38458)

No reviews yet
Full Name
Recombinant Human MHC class I chain-related gene A
Gene Names
MICA; MIC-A; PERB11.1
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Zinc-Alpha 2 Glycoprotein, Active Protein (Cat# AAA38476)

No reviews yet
Full Name
Recombinant Human Zinc-Alpha 2 Glycoprotein
Gene Names
AZGP1; ZAG; ZA2G
Purity
Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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