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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 550-600 of 2567 product results
IL-12 receptor beta 1, Active Protein (Cat# AAA76114)
Full Name
Human IL-12 receptor beta 1 Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
GM-CSF, Active Protein (Cat# AAA79117)
Full Name
Human GM-CSF
Gene Names
CSF2; GMCSF
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
r-3alpha-Hydroxysteroid Dehydrogenase, Active Protein (Cat# AAA78965)
Full Name
r-3alpha-Hydroxysteroid Dehydrogenase (r-3alpha-HSDH (Microorganism)
Pricing
CMV pp65, Active Protein (Cat# AAA224571)
Full Name
CMV pp65 protein (His tag)
Applications
Western Blot
Purity
> 95% pure
Pricing
Bioactivity
(Complement factor B (CFB), a 95-kDa protein, is a crucial catalytic element of the alternative pathway (AP) of complement. After binding of CFB to C3b, activation of the AP depends on the proteolytic cleavage of CFB by factor D to generate the C3 converta)
Complement Factor B (CFB), Active Protein (Cat# AAA153109)
Full Name
Active Complement Factor B (CFB)
Gene Names
Cfb; B; Bf; C2; Fb; H2-Bf; AI195813; AI255840
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Platelet-derived growth factor, Active Protein (Cat# AAA62063)
Full Name
Human platelet-derived growth factor
Gene Names
PDGFB; SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2
Purity
≥ 97% purity (by SDS PAGE and HPLC)
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 20-60 ng/mL in the presence of 10 ng/mL recombinant Activin A.)
ACVR2A, Active Protein (Cat# AAA258184)
Full Name
ACVR2A Protein, Mouse, Recombinant (His & hFc Tag)
Gene Names
Acvr2a; Acvr2; ActrIIa; TactrII
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 10-40 ng/mL in the presence of 10 ng/mL recombinant Activin A.)
ACVR2A, Active Protein (Cat# AAA257856)
Full Name
ACVR2A Protein, Human, Recombinant (hFc Tag)
Gene Names
ACVR2A; ACVR2; ACTRII
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse CD105 at 10 ug/ml (100 ul/well) can bind human TGFRB1 with a linear ranger of 6.4-800 ng/ml.)
alk5, Active Protein (Cat# AAA257886)
Full Name
alk5 Protein, Human, Recombinant (His & hFc Tag)
Gene Names
TGFBR1; AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4
Purity
>85% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized recombinant human Angiopoietin-2 at 10 ug/ml (100 ul/well) can bind Human Tie2 / Fc chimera with a range of 0.2-20 ug/ml.)
Angiopoietin-2, Active Protein (Cat# AAA257912)
Full Name
Angiopoietin-2 Protein, Human, Recombinant (hFc Tag)
Gene Names
ANGPT2; ANG2; AGPT2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human ANGPT2 at 10 ug/ml (100 ul /well) can bind human Tie2-Fch, The EC50 of human Tie2-Fch is 0.1-0.3ug/ml.)
Angiopoietin-2, Active Protein (Cat# AAA257913)
Full Name
Angiopoietin-2 Protein, Human, Recombinant (His Tag)
Gene Names
ANGPT2; ANG2; AGPT2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized Human Ang2 His at 2 ug/ml (100 ul/well) can bind Human TIE2 Fch, the EC50 of Human TIE2 Fch is 80-480 ng/mL.)
Angiopoietin-2, Active Protein (Cat# AAA257914)
Full Name
Angiopoietin-2 Protein, Human, Recombinant (His Tag)
Gene Names
ANGPT2; ANG2; AGPT2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized TNFRSF18-His at 10 ug/mL (100 uL/well) can bind TNFSF18-mFc, the EC50 of TNFSF18-mFc is 20-60 ng/mL.)
GITR, Active Protein (Cat# AAA258024)
Full Name
GITR Protein, Human, Recombinant (ECD, His Tag)
Gene Names
TNFRSF18; AITR; GITR; CD357; GITR-D
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.015-0.06 ug/mL.)
Cardiotrophin 1, Active Protein (Cat# AAA258040)
Full Name
Cardiotrophin 1 Protein, Human, Recombinant (hFc Tag)
Gene Names
CTF1; CT1; CT-1
Purity
>80% as determined by SDS-PAGE
Pricing
WB (Western Blot)
(Sample: Recombinant IL10, Rat;Antibody: Rabbit Anti-Rat IL10 Ab)
Interleukin 10, Active Protein (Cat# AAA150056)
Full Name
Active Interleukin 10 (IL10)
Gene Names
Il10; IL10X
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Figure. Cell proliferation of CTLL-2 cells after stimulated with IL-2.)
Interleukin 2, Active Protein (Cat# AAA150059)
Full Name
Active Interleukin 2 (IL2)
Gene Names
IL2; IL-2; TCGF; lymphokine
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(Aprotinin (AP) is a competitive serine protease inhibitor. Reversibly binds to and blocks the enzymatic active site. Inhibits a range of serine proteases including trypsin, chymotrypsin, kallikrein and plasmin. Inhibits cytopathogenic effect of SARS-CoV-2 and double-stranded RNA formation in SARS-CoV-2-infected cells. The activity of recombinant bovine AP was measured by its ability to inhibit trypsin cleavage of a peptide substrate BAPNA in the assay buffer 200 mM Triethanolamine hydrochloride, 20 mM CaCl2, pH 7.8. The reaction was performed in adding 20 ul 4 mg/mL trypsin diluted by 1mM HCl to 160 ul assay buffer and 20 ul 0.85% (w/v) NaCl and start the reaction by adding 100 ul of 1mg/ml BAPNA. Include a substrate blank containing 160 ul assay buffer, 20 ul 1mM HCl, 20 ul 0.85% (w/v) NaCl and 100 uL of 1mg/ml substrate. Rapidly mixing at 25 degree C, then read at 405 nm in kinetic mode for 5 minutes using a microplate reader controlling the ?A405nm/min=0.08-0.12. The 20 ul different concentrations of recombinant bovine AP was incubated with 20 ul 4 mg/mL trypsin in 160 ul assay buffer at 25 degree C for 10 minutes followed by adding 100 ul substrate, then read at 405 nm in kinetic mode for 5 minutes using a microplate reader. Under these conditions, the enzyme amount of 50% inhibition of trypsin activity per minute is defined as a unit. The specific activity of recombinant bovine AP is >2000 U/mg.)
Aprotinin (AP), Active Protein (Cat# AAA161810)
Full Name
Active Aprotinin (AP)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
Eno1, Active Protein (Cat# AAA48970)
Full Name
Eno1, 1-434aa, Mouse, His-tag, E Coli (Bioactivity Validated)
Gene Names
Eno1; Eno-1; MBP-1; AL022784; 0610008I15
Applications
Enzyme Activity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
CD26/DPP4, Active Protein (Cat# AAA48980)
Full Name
Recombinant human CD26/DPP4 protein
Gene Names
DPP4; CD26; ADABP; ADCP2; DPPIV; TP103
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Ephrin-A5, Active Protein (Cat# AAA48998)
Full Name
Recombinant human Ephrin-A5 protein
Gene Names
EFNA5; AF1; EFL5; RAGS; EPLG7; GLC1M; LERK7
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
RANK/TNFRSF11A, Active Protein (Cat# AAA49004)
Full Name
Recombinant mouse RANK/TNFRSF11A protein
Gene Names
Tnfrsf11a; OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
SDS-PAGE
uGDH, Active Protein (Cat# AAA48625)
Full Name
uGDH, 1-494aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
UGDH; GDH; UGD; UDPGDH; UDP-GlcDH
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
SDS-PAGE
VEGF121, Active Protein (Cat# AAA48513)
Full Name
VEGF121, 207-327aa, Human,His tag, E Coli (Bioactivity Validated)
Gene Names
VEGFA; VPF; VEGF; MVCD1
Applications
SDS-PAGE
Purity
> 90% by SDS PAGE
Pricing
SDS-PAGE
VEGF121, Active Protein (Cat# AAA48532)
Full Name
VEGF121, 207-327aa, Human, E Coli (Bioactivity Validated)
Gene Names
VEGFA; VPF; VEGF; MVCD1
Applications
SDS-PAGE
Purity
> 95% by SDS PAGE
Pricing
Bioactivity
(Human CD40 Ligand/TNFSF5 is coated at 5 ug/ml (100 ul/well) can bind Human CD40/TNFRSF5 (CAT# ATGP4007) in a Functional ELISA assay.)
CD40 Ligand/TNFSF5, Active Protein (Cat# AAA48396)
Full Name
Recombinant human CD40 Ligand/TNFSF5 protein
Gene Names
CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
Bioactivity
(Mouse TNFSF4 is coated at 1 ug/ml (100 ul/well) can bind Human TNFRSF4 (CAT# ATGP3686) in a Functional ELISA assay.)
OX40 Ligand/TNFSF4, Active Protein (Cat# AAA48397)
Full Name
Recombinant mouse OX40 Ligand/TNFSF4 Protein
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
Bioactivity
(Human PDCD1 is coated at 5 ug/ml (100 ul/well) can bind Human PD-L1/B7-H1 (CAT# ATGP3631) in a Functional ELISA assay.)
PD-1, Active Protein (Cat# AAA48399)
Full Name
Recombinant human PD-1 protein
Gene Names
PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
Bioactivity
(Mouse IL-5 in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range )
IL-5, Active Protein (Cat# AAA48400)
Full Name
Recombinant mouse IL-5 protein
Gene Names
Il5; Il-5
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Hydroxyacid Oxidase-1/HAO-1, Active Protein (Cat# AAA48314)
Full Name
Recombinant Hydroxyacid Oxidase-1/HAO-1
Gene Names
Hao1; GOX; Gox1; Hao-1
Applications
Enzyme Activity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Carboxyl Ester Lipase/CEL, Active Protein (Cat# AAA48319)
Full Name
Recombinant Carboxyl Ester Lipase/CEL
Gene Names
Cel; BAL; 1810036E18Rik
Applications
Enzyme Activity, SDS-PAGE
Purity
> 90% by SDS - PAGE
Pricing
Bioactivity
(Human CTLA-4 inhibits Human B7 1/CD80 induced IL-2 secretion of the Jurkat human acute T cell leukemia cells. The ED50 range )
CTLA-4, Active Protein (Cat# AAA48323)
Full Name
Recombinant CTLA-4
Gene Names
CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS - PAGE
Pricing
Bioactivity
(Mouse IL-1 alpha /IL-1F1 stimulates cell proliferation of the D10.G4.1 mouse helper T cells. The ED50 range ? 0.15 ng/ml.)
IL-1 alpha/IL-1F1, Active Protein (Cat# AAA48354)
Full Name
Recombinant mouse IL-1 alpha /IL-1F1 protein
Gene Names
Il1a; Il-1a
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS - PAGE
Pricing
Bioactivity
(Human CSH1 stimulates cell proliferation of the Nb2-11 Rat lymphoma cells. The ED50 range )
Placental Lactogen/CSH1, Active Protein (Cat# AAA48364)
Full Name
Recombinant Human Placental Lactogen/CSH1 Protein
Gene Names
CSH1; PL; CSA; CS-1; CSMT; hCS-1; hCS-A
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
Bioactivity
(Canine IL-1 alpha/IL-1F1 in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 range )
IL-1 alpha/IL-1F1, Active Protein (Cat# AAA48380)
Full Name
Recombinant canine IL-1 alpha/IL-1F1 protein
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
Bioactivity
(Human IgM is coated at 2 ug/ml (100 ul/well) can bind Human pIgR. The ED50 range )
pIgR, Active Protein (Cat# AAA48381)
Full Name
Recombinant human pIgR protein
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
SDS-PAGE
DLD, Active Protein (Cat# AAA48623)
Full Name
DLD, 36-509aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
DLD; E3; LAD; DLDD; DLDH; GCSL; PHE3
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
CD14 CHO, Active Protein (Cat# AAA38511)
Full Name
Recombinant Human CD14 CHO
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
Vascular Endothelial Growth Factor-Sf9, Active Protein (Cat# AAA38118)
Full Name
Recombinant Mouse Vascular Endothelial Growth Factor-Sf9
Gene Names
Vegfa; Vpf; Vegf
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Leptin, Active Protein (Cat# AAA38120)
Full Name
Recombinant Human Leptin
Gene Names
LEP; OB; OBS; LEPD
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Interferon-beta 1b, Active Protein (Cat# AAA38124)
Full Name
Recombinant Human Interferon-beta 1b
Gene Names
IFNB1; IFB; IFF; IFNB
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Insulin Like Growth Factor-1, Active Protein (Cat# AAA38145)
Full Name
Recombinant Rat Insulin Like Growth Factor-1
Purity
Greater than 98.0% as determined by SDS-PAGE.
Pricing
Soluble RANK Ligand, Active Protein (Cat# AAA38163)
Full Name
Recombinant Human Soluble RANK Ligand
Gene Names
TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2
Purity
Greater than 90.0% as determined by analysis by SDS-PAGE.
Pricing
Fibroblast Growth Factor-basic, Active Protein (Cat# AAA38177)
Full Name
Recombinant Human Fibroblast Growth Factor-basic, Sf9
Gene Names
FGF2; BFGF; FGFB; FGF-2; HBGF-2
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Granulocyte Macrophage-Colony Stimulating Factor, Active Protein (Cat# AAA38190)
Full Name
Recombinant Porcine Granulocyte Macrophage-Colony Stimulating Factor
Gene Names
CSF2; GM-CSF
Purity
Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Pricing
Platelet Derived Growth Factor-BB, Active Protein (Cat# AAA38195)
Full Name
Recombinant Mouse Platelet Derived Growth Factor-BB
Gene Names
Pdgfb; Sis; PDGF-B
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
TNF-Related Apoptosis Inducing Ligand/Apo2L, Active Protein (Cat# AAA38208)
Full Name
Recombinant Human TNF-Related Apoptosis Inducing Ligand/Apo2L
Gene Names
TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Resistin, Active Protein (Cat# AAA38215)
Full Name
Recombinant Human Resistin
Gene Names
RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
Purity
Greater than 98% as determined by SDS-PAGE.
Pricing
Leptin, Active Protein (Cat# AAA38234)
Full Name
Recombinant Horse Leptin
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Urate Oxidase, Active Protein (Cat# AAA38272)
Full Name
Recombinant Urate Oxidase
Gene Names
Uox; Uri; Uri2; UOX-2
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
Deoxyribonuclease I, Active Protein (Cat# AAA38277)
Full Name
Recombinant Human Deoxyribonuclease I
Gene Names
DNASE1; DNL1; DRNI
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.