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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 450-500 of 2875 product results
Galectin-3, Active Protein (Cat# AAA79140)
Full Name
Human Galectin-3
Gene Names
LGALS3; L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
Complement C7, Active Protein (Cat# AAA75234)
Full Name
Complement C7 protein
Purity
> 98% pure
Pricing
CD40, Active Protein (Cat# AAA75431)
Full Name
CD40 protein (Mouse)
Gene Names
CD40; p50; Bp50; CDW40; TNFRSF5
Purity
> 98% pure
Pricing
Granulocyte Macrophage, Active Protein (Cat# AAA38831)
Full Name
Recombinant Rhesus Macaque Granulocyte Macrophage-Colony Stimulating Factor
Purity
Greater than 95.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Pricing
Ciliary Neurotrophic Factor, Active Protein (Cat# AAA38894)
Full Name
Recombinant Mouse Ciliary Neurotrophic Factor
Gene Names
Cntf; AI429687
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Lactate Dehydrogenase B, Active Protein (Cat# AAA38250)
Full Name
Recombinant Lactate Dehydrogenase B
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Application Data
Fibroblast Growth Factor 1, Acidic (FGF1), Active Protein (Cat# AAA148139)
Full Name
Active Fibroblast Growth Factor 1, Acidic (FGF1)
Gene Names
FGF1; AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
(Measured by its ability to promote proliferation of INS-1 cells. The ED50 for this effect is typically 50-500 ng/mL.)
Prolactin, Active Protein (Cat# AAA258158)
Full Name
Prolactin Protein, Mouse, Recombinant (His Tag)
Purity
>92% as determined by SDS-PAGE
Pricing
Catalase, Active Protein (Cat# AAA38978)
Full Name
Recombinant Human Catalase
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
Interleukin-27, Active Protein (Cat# AAA38595)
Full Name
Recombinant Mouse Interleukin-27
Gene Names
Il27; p28; Il30; IL-27; IL-27p28
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Fibroblast Growth Factor-8, Active Protein (Cat# AAA38889)
Full Name
Recombinant Mouse Fibroblast Growth Factor-8
Gene Names
Fgf8; Aigf; Fgf-8
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
IL21, Active Protein (Cat# AAA75599)
Full Name
IL21 protein
Gene Names
IL21; Za11; IL-21; CVID11
Purity
> 95.0% by SDS-PAGE
Pricing
CTGF, Active Protein (Cat# AAA75454)
Full Name
CTGF protein
Gene Names
CTGF; CCN2
Purity
> 95% pure
Pricing
Bioactivity
(Figure 2. The dose-effect curve of IL-2 on Splenic lymphocytes cells.)
Interleukin 2 (IL2), Active Protein (Cat# AAA152965)
Full Name
Active Interleukin 2 (IL2)
Gene Names
IL2; IL-2; TCGF; POIL2
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with TNFalpha.)
Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA152991)
Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
TNF; TNFa
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
SDS-PAGE
Noggin (NOG), Active Protein (Cat# AAA148248)
Full Name
Active Noggin (NOG)
Reactivity
Rat
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized VEGF C-his at 2 ug/mL (100 uL/well) can bind VEGFR3-His, Biotinylated, the EC50 of VEGFR3-His, Biotinylated is 1-10 ng/mL.)
VEGF C, Active Protein (Cat# AAA257893)
Full Name
VEGF C Protein, Human, Recombinant (His Tag)
Gene Names
VEGFC; VRP; Flt4-L
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TNF, Active Protein (Cat# AAA214321)
Full Name
Recombinant Mouse TNF
Gene Names
Tnf; DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
SDS-PAGE
Epidermal Growth Factor (EGF), Active Protein (Cat# AAA148240)
Full Name
Active Epidermal Growth Factor (EGF)
Gene Names
EGF; URG; HOMG4
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Bioactivity
(Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.Thus, chemotaxis assay used 24-well microchemotaxis syste)
Interleukin 8 (IL8), Active Protein (Cat# AAA152973)
Full Name
Active Interleukin 8 (IL8)
Gene Names
CXCL8; IL8
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Leptin, Active Protein (Cat# AAA38120)
Full Name
Recombinant Human Leptin
Gene Names
LEP; OB; OBS; LEPD
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Bioactivity
(Human PDCD1 is coated at 5 ug/ml (100 ul/well) can bind Human PD-L1/B7-H1 (CAT# ATGP3631) in a Functional ELISA assay.)
PD-1, Active Protein (Cat# AAA48399)
Full Name
Recombinant human PD-1 protein
Gene Names
PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
GDF3, Active Protein (Cat# AAA75443)
Full Name
GDF3 protein
Gene Names
GDF3; KFS3; MCOP7; MCOPCB6
Purity
= > 98% by SDS-PAGE and HPLC
Pricing
Application Data
LIF, Active Protein (Cat# AAA214240)
Full Name
Recombinant Human LIF
Gene Names
LIF; CDF; DIA; HILDA; MLPLI
Purity
>95% as determined by SDS-PAGE
Pricing
SDS-PAGE
Hemopexin, Active Protein (Cat# AAA257938)
Full Name
Hemopexin Protein, Human, Recombinant (His Tag)
Gene Names
HPX; HX
Purity
>96% as determined by SDS-PAGE
Pricing
Application Data
VEGF-C, Active Protein (Cat# AAA79210)
Full Name
Rat VEGF-C
Reactivity
Rat
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Thioredoxin Reductase, Active Protein (Cat# AAA78970)
Full Name
Thioredoxin Reductase (yeast) (rNTR (yeast))
Pricing
CD80 (B7-1), Active Protein (Cat# AAA76106)
Full Name
Mouse CD80 Recombinant (B7-1)
Purity
>90%, as determined by SDS-PAGE and HPLC
Pricing
Brain-Derived Neurotrophic Factor (BDNF), Active Protein (Cat# AAA235614)
Full Name
Recombinant Human Brain-Derived Neurotrophic Factor (BDNF) Active
Gene Names
BDNF; ANON2; BULN2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Glial-Derived Neurotrophic Factor, Active Protein (Cat# AAA38153)
Full Name
Recombinant Human Glial-Derived Neurotrophic Factor
Gene Names
GDNF; ATF1; ATF2; HSCR3; HFB1-GDNF
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
IGF-1, Active Protein (Cat# AAA79164)
Full Name
Human IGF-1
Gene Names
IGF1; IGFI; IGF-I; IGF1A
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
Bioactivity
(Hemoglobin (HB) is a protein in red blood cells which contains iron. It is used to transport oxygen around the human body. Hemoglobin is found in the red blood cells of almost all vertebrates. Hemoglobin has peroxidase activity. In the presence of hydrogen peroxide, hemoglobin can catalyze the substrates 3,3 ', 5,5' - tetramethylbenzidine (TMB) to produce a blue compound which has a maximum absorption at 595 nm. Thus, the activity of native chinese hamster hemoglobin was measured by its ability to catalyze the substrates of TMB. The reaction was performed in PBS, pH 7.4 (Assay Buffer), ainitiated by addition 40 uL of various concentrations of HB (diluted by Assay Buffer) to 160 uL of TMB. Incubated at 37 degree C for 20min, then read at a wavelength of 595 nm immediately. The result was shown in figure 1, and the OD value was in a linear relationship with the concentration of HB.)
Hemoglobin (HB), Active Protein (Cat# AAA161849)
Full Name
Active Hemoglobin (HB)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
SDS-PAGE
(Figure. SDS-PAGE)
Platelet Factor 4 (PF4), Active Protein (Cat# AAA150559)
Full Name
Active Platelet Factor 4 (PF4)
Gene Names
PF4; PF-4; CXCL4; SCYB4
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Application Data
Interferon Gamma (IFNg), Active Protein (Cat# AAA146602)
Full Name
Active Interferon Gamma (IFNg)
Gene Names
Ifng; Ifg; IFN-g
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Matrix Metalloproteinase 13 (MMP13), Active Protein (Cat# AAA148163)
Full Name
Active Matrix Metalloproteinase 13 (MMP13)
Reactivity
Rat
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Plasminogen (Plg), Active Protein (Cat# AAA148189)
Full Name
Active Plasminogen (Plg)
Gene Names
Plg; Ab1-346
Reactivity
Rat
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
(Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.04-0.2 ng/mL.)
FGF1, Active Protein (Cat# AAA258139)
Full Name
FGF1 Protein, Mouse, Rat, Recombinant
Gene Names
Fgf1; Fam; Fgfa; Dffrx; Fgf-1
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
COVID 19 Papain-Like Protease Coronavirus, Active Protein (Cat# AAA268910)
Full Name
Recombinant 2019-nCoV Papain-Like Protease (E.coli)
Purity
>90% as determined by reducing SDS-PAGE.
Pricing
Sequence
Vimentin (VIM), Active Protein (Cat# AAA150975)
Full Name
Active Vimentin (VIM)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
SDS-PAGE
((Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.)
Endothelin-1 (EDN1), Active Protein (Cat# AAA113186)
Full Name
Recombinant Human Endothelin-1 (EDN1) (Active)
Gene Names
EDN1; ET1; QME; PPET1; ARCND3; HDLCQ7
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing
Lactate Dehydrogenase 2, Active Protein (Cat# AAA44810)
Full Name
Lactate Dehydrogenase 2 (LDH-2), Human Erythrocytes
Pricing
Vascular Endothelial Growth Factor, Active Protein (Cat# AAA38137)
Full Name
Recombinant Human Vascular Endothelial Growth Factor, CHO
Gene Names
VEGFA; VPF; VEGF; MVCD1
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Bone Morphogenetic protein-13, Active Protein (Cat# AAA38030)
Full Name
Recombinant Human Bone Morphogenetic protein-13
Gene Names
GDF6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; LCA17; MCOP4; SCDO4; BMP-13; MCOPCB6
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Galectin-1, Active Protein (Cat# AAA79251)
Full Name
Human Galectin-1
Gene Names
LGALS1; GBP; GAL1
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
IL2RA (CD25), Active Protein (Cat# AAA76070)
Full Name
Human IL2RA Recombinant (CD25)
Purity
>97%, as determined by SDS-PAGE and HPLC
Pricing
SDS_PAGE
(Sample: Active recombinant GZMK, Mouse)
Granzyme K (GZMK), Active Protein (Cat# AAA161832)
Full Name
Active Granzyme K (GZMK)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Application Data
IL17, Active Protein (Cat# AAA214331)
Full Name
Recombinant Mouse IL17
Gene Names
Il17a; Il17; Ctla8; IL-17; Ctla-8; IL-17A
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human BCL2-His at 10 ug/ml (100 ul/well) can bind biotinylated mouse BCL2L1-His, The EC50 of biotinylated mouse BCL2L1-His is 0.07-0.15 ug/ml.)
Bcl-2, Active Protein (Cat# AAA257842)
Full Name
Bcl-2 Protein, Human, Recombinant (His Tag)
Gene Names
BCL2; Bcl-2; PPP1R50
Purity
>90% as determined by SDS-PAGE
Pricing
VEGFR-2/KDR-Fc Chimera, soluble, Active Protein (Cat# AAA79265)
Full Name
Human VEGFR-2/KDR-Fc Chimera, soluble
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Human
Purity
> 90% by SDS-PAGE & silver stain
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.