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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 500-550 of 2567 product results


Glial-Derived Neurotrophic Factor, Active Protein (Cat# AAA38153)

No reviews yet
Full Name
Recombinant Human Glial-Derived Neurotrophic Factor
Gene Names
GDNF; ATF1; ATF2; HSCR3; HFB1-GDNF
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Prolactin, Active Protein (Cat# AAA38156)

No reviews yet
Full Name
Recombinant Mouse Prolactin
Gene Names
Prl; Prl1a1; AV290867
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Flt3-Ligand, Active Protein (Cat# AAA38167)

No reviews yet
Full Name
Recombinant Mouse Flt3-Ligand
Gene Names
Flt3l; Ly72L; Flt3lg
Purity
Greater than 98.0% as determined by SDS-PAGE.
Pricing

Interleukin-15, Active Protein (Cat# AAA38169)

No reviews yet
Full Name
Recombinant Rat Interleukin-15
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

Desert HedgeHog, Active Protein (Cat# AAA38175)

No reviews yet
Full Name
Recombinant Human Desert HedgeHog (C23II)
Gene Names
DHH; GDXYM; HHG-3; SRXY7
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Fibroblast Growth Factor-23, Active Protein (Cat# AAA38181)

No reviews yet
Full Name
Recombinant Human Fibroblast Growth Factor-23 His Tag
Gene Names
FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC
Purity
Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Granulocyte Macrophage-Colony Stimulating Factor, Active Protein (Cat# AAA38187)

No reviews yet
Full Name
Recombinant Rat Granulocyte Macrophage-Colony Stimulating Factor
Gene Names
Csf2; Gmcsf; Gm-csf
Purity
Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Pricing

Interleukin-21, Active Protein (Cat# AAA38193)

No reviews yet
Full Name
Recombinant Human Interleukin-21
Gene Names
IL21; Za11; IL-21; CVID11
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing

Thioredoxin-2, Active Protein (Cat# AAA38639)

No reviews yet
Full Name
Recombinant Human Thioredoxin-2
Gene Names
TXN2; MTRX; TRX2; MT-TRX
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Glutathione S-Transferase pi 1, Active Protein (Cat# AAA38686)

No reviews yet
Full Name
Recombinant Human Glutathione S-Transferase pi 1
Gene Names
GSTP1; PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Non-Muscle Myosin-II Regulatory Light Chain, Active Protein (Cat# AAA38457)

No reviews yet
Full Name
Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Uracil DNA Glycosylase, Active Protein (Cat# AAA38290)

No reviews yet
Full Name
Uracil DNA Glycosylase
Pricing

Interleukin-33, Active Protein (Cat# AAA38972)

No reviews yet
Full Name
Recombinant Rat Interleukin-33
Gene Names
Il33; RGD1311155
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Catalase, Active Protein (Cat# AAA38978)

No reviews yet
Full Name
Recombinant Human Catalase
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

Fibroblast Growth Factor-8, Active Protein (Cat# AAA38889)

No reviews yet
Full Name
Recombinant Mouse Fibroblast Growth Factor-8
Gene Names
Fgf8; Aigf; Fgf-8
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Parathyroid Hormone, Active Protein (Cat# AAA38891)

No reviews yet
Full Name
Recombinant Human Parathyroid Hormone (1-84) N15 Labeled
Gene Names
PTH; PTH1
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Monocyte Chemotactic Protein-1/MCAF, Active Protein (Cat# AAA38081)

No reviews yet
Full Name
Recombinant Human Monocyte Chemotactic Protein-1/MCAF (CCL2)
Gene Names
CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Macrophage Inflammatory protein-1 beta, Active Protein (Cat# AAA38083)

No reviews yet
Full Name
Recombinant Human Macrophage Inflammatory protein-1 beta (CCL4)
Gene Names
CCL4; ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
Purity
Greater than 99.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Monocyte Chemotactic Protein-3, Active Protein (Cat# AAA38087)

No reviews yet
Full Name
Recombinant Human Monocyte Chemotactic Protein-3 (CCL7)
Gene Names
CCL7; FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

GRO-alpha, Active Protein (Cat# AAA38089)

No reviews yet
Full Name
Recombinant Human GRO-alpha (CXCL1)
Gene Names
CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

IL-6 Receptor (IL-6R), Active Protein (Cat# AAA76077)

No reviews yet
Full Name
Human IL-6 Receptor Recombinant (IL-6R)
Purity
>97%, as determined by SDS-PAGE and HPLC
Pricing

IL-12 receptor beta 1, Active Protein (Cat# AAA76114)

No reviews yet
Full Name
Human IL-12 receptor beta 1 Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
product-image-AAA79117_AD13.jpg Application Data

GM-CSF, Active Protein (Cat# AAA79117)

No reviews yet
Full Name
Human GM-CSF
Gene Names
CSF2; GMCSF
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing

r-3alpha-Hydroxysteroid Dehydrogenase, Active Protein (Cat# AAA78965)

No reviews yet
Full Name
r-3alpha-Hydroxysteroid Dehydrogenase (r-3alpha-HSDH (Microorganism)
Pricing
product-image-AAA48387_BIOACTIVITY13.jpg Bioactivity (Human Proinsulin in a cell proliferation assay using MCF7 human breast cancer cell. The ED50 range )

NRG1/HRG1, Active Protein (Cat# AAA48387)

No reviews yet
Full Name
Recombinant human NRG1/HRG1 protein
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
product-image-AAA48393_BIOACTIVITY13.jpg Bioactivity (Human BTC stimulates cell proliferation of the Balb/3T3 mouse embryonic fibroblast cells. The ED50 range )

Betacellulin/BTC, Active Protein (Cat# AAA48393)

No reviews yet
Full Name
Recombinant human Betacellulin/BTC Protein
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
product-image-AAA48408_BIOACTIVITY13.jpg Bioactivity (Mouse Ctla4 inhibits IL-2 secretion of the stimulated Jurkat human acute T cell leukemia cells with Human B7-1/CD80. The ED50 range )

Ctla-4, Active Protein (Cat# AAA48408)

No reviews yet
Full Name
Recombinant mouse Ctla-4 protein
Gene Names
Ctla4; Cd152; Ly-56; Ctla-4
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
product-image-AAA48456_AD13.jpg Application Data (Human G-CSF stimulates cell proliferation of the M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range )

G-CSF, Active Protein (Cat# AAA48456)

No reviews yet
Full Name
G-CSF, 31-204 aa, Human, E Coli (Bioactivity Validated)
Gene Names
CSF3; GCSF; CSF3OS; C17orf33
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48461_BIOACTIVITY13.jpg Bioactivity (Human Prolactin in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range is less than or equal to 0.5ng/ml.)

Prolactin, Active Protein (Cat# AAA48461)

No reviews yet
Full Name
Prolactin, 29-227aa, Human, E Coli (Bioactivity Validated)
Gene Names
PRL; GHA1
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48316_SDS_PAGE15.jpg SDS-PAGE (3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)

Caspase-3, Active Protein (Cat# AAA48316)

No reviews yet
Full Name
Recombinant Caspase-3
Gene Names
CASP3; CPP32; SCA-1; CPP32B
Applications
Enzyme Activity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
product-image-AAA48369_BIOACTIVITY13.jpg Bioactivity (SARS-CoV Spike RBD is coated at 5ug/ml (100 ul/well) can bind ACE-2 (CAT# ATGP3963) in a Functional ELISA assay.)

COVID 19 Spike RBD Coronavirus, Active Protein (Cat# AAA48369)

No reviews yet
Full Name
Recombinant SARS-CoV Spike RBD protein
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
product-image-AAA48516_SDS_PAGE15.jpg SDS-PAGE

Cyclophilin F, Active Protein (Cat# AAA48516)

No reviews yet
Full Name
Cyclophilin F (PPIF), 30-207aa, Human,His tag, E Coli (Bioactivity Validated)
Gene Names
PPIF; CYP3; CypD; CyP-M; Cyp-D
Applications
SDS-PAGE
Purity
> 95% by SDS PAGE
Pricing
product-image-AAA48543_SDS_PAGE15.jpg SDS-PAGE

GSTP1, Active Protein (Cat# AAA48543)

No reviews yet
Full Name
GSTP1, 1-210aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
GSTP1; PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48677_SDS_PAGE15.jpg SDS-PAGE

BLMH, Active Protein (Cat# AAA48677)

No reviews yet
Full Name
BLMH, 1-455aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
BLMH; BH; BMH
Applications
SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing

Lactate Dehydrogenase 4, Active Protein (Cat# AAA44812)

No reviews yet
Full Name
Lactate Dehydrogenase 4 (LDH-4), Human Liver
Pricing
product-image-AAA48925_SDS_PAGE15.jpg SDS-PAGE

NME3, Active Protein (Cat# AAA48925)

No reviews yet
Full Name
NME3, 22-169aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
NME3; NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
product-image-AAA48930_SDS_PAGE15.jpg SDS-PAGE (3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)

IDO1, Active Protein (Cat# AAA48930)

No reviews yet
Full Name
IDO1, 1-403aa, Human, His-tag, E Coli (Bioactivity Validated)
Gene Names
IDO1; IDO; INDO; IDO-1
Applications
SDS-PAGE, Enzyme Activity
Purity
> 90% by SDS-PAGE
Pricing

IFN-omega, Active Protein (Cat# AAA48989)

No reviews yet
Full Name
Recombinant human IFN-omega protein
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing

PlGF-1/PGF, Active Protein (Cat# AAA48993)

No reviews yet
Full Name
Recombinant human PlGF-1/PGF protein
Gene Names
PGF; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing

TRANCE/RANK L/TNFSF11, Active Protein (Cat# AAA49005)

No reviews yet
Full Name
Recombinant human TRANCE/RANK L/TNFSF11 protein
Gene Names
TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TRANCE; hRANKL2
Applications
Bioactivity, SDS-PAGE
Purity
> 85% by SDS-PAGE
Pricing

IL-7, Active Protein (Cat# AAA49006)

No reviews yet
Full Name
Recombinant human IL-7 protein
Gene Names
IL7; IL-7
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing

VEGFR1/Flt-1, Active Protein (Cat# AAA49007)

No reviews yet
Full Name
Recombinant mouse VEGFR1/Flt-1 protein
Gene Names
Flt1; Flt-1; sFlt1; VEGFR1; VEGFR-1; AI323757
Applications
Bioactivity, SDS-PAGE
Purity
> 85% by SDS-PAGE
Pricing

Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF), Active Protein (Cat# AAA47951)

No reviews yet
Full Name
Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF)
Gene Names
CSF2; GMCSF; MGC131935; MGC138897
Purity
>98% as determined by RPHPLC and SDS-PAGE.
Pricing

CCL19, Active Protein (Cat# AAA47963)

No reviews yet
Full Name
Recombinant CCL19 (MIP-3β)
Gene Names
CCL19; ELC; CKb11; MIP3B; MIP-3b; SCYA19
Purity
>97% by SDS-PAGE
Pricing
product-image-AAA258011_AD13.png Application Data (1. Measured by its binding ability in a functional ELISA. Immobilized human CD2-His at 10 ug/ml (100 ul/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.1 ug/ml. 2. Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CD2-His at 10 ug/ml (100 ul/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.10 ug/ml.)

CD58, Active Protein (Cat# AAA258011)

No reviews yet
Full Name
CD58 Protein, Human, Recombinant (hFc Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258033_AD11.png Application Data (Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 1-5 ng/mL.)

VEGF121b, Active Protein (Cat# AAA258033)

No reviews yet
Full Name
VEGF121b Protein, Human, Recombinant
Gene Names
VEGFA; VPF; VEGF; MVCD1
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258062_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human CD47 at 2 ug/ml (100 ul/well) can bind human SIRPa(V2)-His, the EC50 of human SIRPa(V2)-His is 200-800 ng/mL.)

SIRP alpha, Active Protein (Cat# AAA258062)

No reviews yet
Full Name
SIRP alpha Protein, Human, Recombinant (ECD, SIRP alphaV2, His Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258252_AD13.png Application Data (Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombinant human BMP-9.)

ALK-1, Active Protein (Cat# AAA258252)

No reviews yet
Full Name
ALK-1 Protein, Canine, Recombinant (hFc Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258136_AD13.png Application Data (Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 10-50 ng/mL in the presence of 10 ng/mL recombinant Activin A.)

ACVR2B, Active Protein (Cat# AAA258136)

No reviews yet
Full Name
ACVR2B Protein, Mouse, Recombinant (His & hFc Tag)
Gene Names
Acvr2b; ActRIIB
Purity
>97% as determined by SDS-PAGE
Pricing
product-image-AAA257825_AD13.png Application Data (Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.)

ALK-1, Active Protein (Cat# AAA257825)

No reviews yet
Full Name
ALK-1 Protein, Human, Recombinant (hFc Tag)
Gene Names
ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Purity
>97% as determined by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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