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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1300-1350 of 2567 product results
Application Data
(Measured by its ability to bind human EGF in a functional ELISA.)
EGFR, Active Protein (Cat# AAA258225)
Full Name
EGFR Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Egfr; Wa5; wa2; Erbb; Errp; wa-2; Errb1; AI552599; 9030024J15Rik
Purity
>90% as determined by SDS-PAGE
Pricing
SDS-PAGE
TrkA, Active Protein (Cat# AAA258229)
Full Name
TrkA Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Ntrk1; Tkr; trk; TrkA; C80751
Purity
> 90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EFNA5-His at 10 ug/ml (100 ul/well) can bind mouse EPHA3-Fc, The EC50 of rat mouse EPHA3-Fc is 12.3-28.9 ng/ml.)
EphA3, Active Protein (Cat# AAA258234)
Full Name
EphA3 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Epha3; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4; AW492086
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA3-His at 10 ug/mL (100 uL/well) can bind mouse EFNA5-Fc. The EC50 of mouse EFNA5-Fc is 4.9-11.4 ng/mL.)
EphA3, Active Protein (Cat# AAA258235)
Full Name
EphA3 Protein, Mouse, Recombinant (His Tag)
Gene Names
Epha3; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4; AW492086
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EPHB2-His at 10 ug/mL (100 uL/well) can bind mouse EFNB2-Fc. The EC50 of mouse EFNB2-Fc is 0.01-0.03 ug/mL.)
EphB2, Active Protein (Cat# AAA258241)
Full Name
EphB2 Protein, Mouse, Recombinant (His Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human EphB4-His at 10 ug/ml (100 ul/well) can bind zebrafish EFNB2A-Fc, The EC50 of zebrafish EFNB2A-Fc is 12.8-30.1 ng/ml.)
EFNB2A, Active Protein (Cat# AAA258248)
Full Name
EFNB2A Protein, Danio rerio (zebrafish), Recombinant (hFc Tag)
Gene Names
efnb2a; efnb2; ephrin-B2a; id:ibd5072
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human EphB4-His at 10 ug/mL (100 uL/well) can bind canine EFNB2-Fc3. The EC50 of canine EFNB2-Fc3 is 25.8-60.2 ng/mL.)
Ephrin B2, Active Protein (Cat# AAA258255)
Full Name
Ephrin B2 Protein, Canine, Recombinant (hFc Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 for this effect is typically 0.2-2 ug/mL.)
Neuregulin-1, Active Protein (Cat# AAA258258)
Full Name
Neuregulin-1 Protein, Canine, Recombinant (ECD, His Tag)
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit mouse CSF induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 50-250 ng/mL in the presence of 2.5 ng/mL Recombinant Mouse M-CSF.)
CSF1R, Active Protein (Cat# AAA258261)
Full Name
CSF1R Protein, Rat, Recombinant (hFc Tag)
Gene Names
Csf1r; c-fms; mrfms; CSF-1R; CSF-1-R; M-CSF-R
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized TIGIT Protein, Human, Recombinant (mFc Tag) at 2 ug/ml (100 ul/well) can bind CD155/PVR Protein, Rhesus, Recombinant (His Tag), the EC50 of CD155/PVR Protein, Rhesus, Recombinant (His Tag)is 200-900 ng/mL.)
CD155/PVR, Active Protein (Cat# AAA258263)
Full Name
CD155/PVR Protein, Rhesus, Recombinant (His Tag)
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 60-300 ng/ml.)
PDGF-C, Active Protein (Cat# AAA258264)
Full Name
PDGF-C Protein, Cynomolgus, Recombinant (hFc Tag)
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
COVID 19 Spike RBD(N501Y)-His Coronavirus, Active Protein (Cat# AAA258103)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD(N501Y)-His Recombinant Protein
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized ACE2 Protein, Human, Recombinant (mFc Tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD (L452R, E484Q) Protein (His Tag), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD (L452R, E484Q) Protein (His Tag) is 5.0-30.0 ng/mL.)
COVID 19 Spike RBD (L452R, E484Q) Protein (His Tag) Coronavirus, Active Protein (Cat# AAA258108)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD (L452R, E484Q) Protein (His Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD-AVI & His Recombinant Protein, Biotinylated(40592-V27B-B),the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD-AVI & His Recombinant Protein, Biotinylated (40592-V27B-B) is 17-40 ng/mL.)
COVID 19 Spike RBD-AVI & His Coronavirus, Active Protein (Cat# AAA258109)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD-AVI & His Recombinant Protein, Biotinylated
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to cleave a peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans.The specific activity is >5 pmols/min/ug.)
COVID 19 3CLpro/3C-like protease-His Coronavirus, Active Protein (Cat# AAA258110)
Full Name
SARS-CoV-2 (2019-nCoV) 3CLpro/3C-like protease-His Recombinant Protein
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 5-25 ng/mL in the presence of 10 ng/mL rhActivin A.)
FSTL3, Active Protein (Cat# AAA258117)
Full Name
FSTL3 Protein, Mouse, Recombinant (His Tag)
Gene Names
Fstl3; Flrg; E030038F23Rik
Purity
>85% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 40-200 ng/mL in the presence of 10 ng/mL rhActivin A.)
Follistatin, Active Protein (Cat# AAA258120)
Full Name
Follistatin Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Fst; FS; AL033346
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse CD86 at 20 ug/ml (100 ul/well) can bind mouse CD28 with a linear ranger of 6.4-800 ng/ml.)
CD86, Active Protein (Cat# AAA258125)
Full Name
CD86 Protein, Mouse, Recombinant (His Tag)
Gene Names
Cd86; B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2
Purity
>92% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit BMP4-induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 0.1-0.3 ug/ml in the presence of 50 ng/mL of recombinant human BMP4.)
BMPR1A/ALK-3, Active Protein (Cat# AAA258126)
Full Name
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc Tag)
Gene Names
Bmpr1a; ALK3; Bmpr; BMPR-IA; AU045487; 1110037I22Rik
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using NIH3T3 cells. The ED50 for this effect is typically 8-32 ng/mL.)
Oncostatin M/OSM, Active Protein (Cat# AAA258129)
Full Name
Oncostatin M/OSM Protein, Mouse, Recombinant
Gene Names
Osm; OncoM
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human uPA at 5 ug/ml (100 ul/well) can bind mouse PLAUR with a linear ranger of 1.6-40 ng/ml.)
uPAR/PLAUR, Active Protein (Cat# AAA258134)
Full Name
uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc Tag)
Gene Names
Plaur; Cd87; uPAR; u-PAR
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to bind with uPA-His in a functional ELISA.)
uPAR/PLAUR, Active Protein (Cat# AAA258135)
Full Name
uPAR/PLAUR Protein, Mouse, Recombinant (His Tag)
Gene Names
Plaur; Cd87; uPAR; u-PAR
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 10-50 ng/mL.)
TWEAK/TNFSF12, Active Protein (Cat# AAA258138)
Full Name
TWEAK/TNFSF12 Protein, Mouse, Recombinant (rFc Tag)
Gene Names
Tnfsf12; Dr3l; Apo3l; Dr3lg; Tweak
Purity
>90 ? as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.04-0.2 ng/mL.)
FGF1, Active Protein (Cat# AAA258139)
Full Name
FGF1 Protein, Mouse, Rat, Recombinant
Gene Names
Fgf1; Fam; Fgfa; Dffrx; Fgf-1
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit mouse FGF acidic (aFGF/FGF1) dependent proliferation of Balb/C 3T3 mouse fibroblasts. The ED50 for this effect is typically 6-25 ng/mL in the presence of 0.5 ng/mL of mouse FGF acidic (aFGF/FGF1).)
FGFR1, Active Protein (Cat# AAA258140)
Full Name
FGFR1 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Fgfr1; FLG; MFR; Eask; Hspy; Flt-2; c-fgr; Fgfr-1; AW208770; bFGF-R-1
Purity
>97% as determined by SDS-PAGE
Pricing
SDS-PAGE
LRPAP1, Active Protein (Cat# AAA258151)
Full Name
LRPAP1 Protein, Mouse, Recombinant (His Tag)
Gene Names
Lrpap1; RAP; HBP44; C77774; AA617339; AI790446; AU042172
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to induce activation of beta-catenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 0.1-0.9 ug/ml in the presence of 5 ng/ml recombinant mouse Wnt3a.)
RSPO1, Active Protein (Cat# AAA258154)
Full Name
RSPO1 Protein, Mouse, Recombinant (His Tag)
Gene Names
Rspo1; Rspondin; R-spondin
Purity
>95% as determined by SDS-PAGE
Pricing
SDS-PAGE
Carbonic Anhydrase IV, Active Protein (Cat# AAA258156)
Full Name
Carbonic Anhydrase IV Protein, Mouse, Recombinant (His Tag)
Gene Names
Car4; Ca4; AW456718
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using MCF-7 cells. The ED50 for this effect is 0.2-1.2 ug/mL.)
IGF1, Active Protein (Cat# AAA258162)
Full Name
IGF1 Protein, Mouse, Recombinant
Gene Names
Igf1; Igf-1; Igf-I; C730016P09Rik
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.05-0.3ug/mL when stimulated with 1 ug/mL Recombinant Human B7-1/CD80.)
CTLA-4, Active Protein (Cat# AAA258168)
Full Name
CTLA-4 Protein, Mouse, Recombinant (ECD, hFc Tag)
Gene Names
Ctla4; Cd152; Ly-56; Ctla-4
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized Mouse Ephrin B2 His at 2 ug/ml (100 ul/well) can bind Mouse EphB4 hFc, the EC50 of Mouse EphB4 hFc is 2.0-10.0 ng/mL.)
EphB4, Active Protein (Cat# AAA258173)
Full Name
EphB4 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Ephb4; Htk; MDK2; Myk1; Tyro11; AI042935; b2b2412Clo
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized human VEGF-C at 10 ug/mL (100 uL/well) can bind mouse VEGFR3-Fc. The EC50 of mouse VEGFR3-Fc is 0.008 ug/mL.)
VEGFR3/FLT4, Active Protein (Cat# AAA258175)
Full Name
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Flt4; Chy; Flt-4; VEGFR3; VEGFR-3; AI323512
Purity
>92% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human HGF at 2 ug/ml (100 ul/well) can bind mouse HGFR with a linear ranger of 1.28-32ng/ml.)
c-MET, Active Protein (Cat# AAA258186)
Full Name
c-MET Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Met; HGF; HGFR; Par4; c-Met; AI838057
Purity
>92% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EphrinA3 at 1 ug/ml (100 ul/well) can bind mouse EPHA6 / chimera with a linear ranger of 6.25-400 ng/ml.)
EphA6, Active Protein (Cat# AAA258187)
Full Name
EphA6 Protein, Mouse, Recombinant (hFc Tag)
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse EphA6 at 2 ug/ml (100 ul/well) can bind recombinant human EphrinA3 at a linear range of 0.31-10 ng/ml.)
EphA6, Active Protein (Cat# AAA258188)
Full Name
EphA6 Protein, Mouse, Recombinant (His Tag)
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. 1. Immobilized human ACVR2B at 10 ug/mL (100 ul/well) can bind biotinylated mouse INHBA-His, The EC50 of biotinylated mouse INHBA-His is 0.161 ug/mL. 2. Immobilized mouse INHBA-his at 10 ug/mL (100 ul/well) can bind human Follistatin Protein, The EC50 of human Follistatin Protein is 0.39 ug/mL.)
Inhibin beta A/Activin A, Active Protein (Cat# AAA258193)
Full Name
Inhibin beta A/Activin A Protein, Mouse, Recombinant (His Tag)
Purity
>88% as determined by SDS-PAGE
Pricing
SDS-PAGE
Carbonic Anhydrase IX, Active Protein (Cat# AAA258194)
Full Name
Carbonic Anhydrase IX Protein, Mouse, Recombinant (His Tag)
Gene Names
Car9; Ca9; CAIX; MN/CA9
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized Mouse IFNGR1-His at 2 ug/mL (100 ul/well) can bind mouse IFNG-Fc, The EC50 of mouse IFNG-Fc is 20-100 ng/mL.)
IFNGR1, Active Protein (Cat# AAA258196)
Full Name
IFNGR1 Protein, Mouse, Recombinant (His Tag)
Gene Names
Ifngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
(Measured in antiviral assay using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is typically 0.2-1 ng/mL.)
Interferon Gamma, Active Protein (Cat# AAA258198)
Full Name
Interferon Gamma Protein, Mouse, Recombinant (His Tag)
Gene Names
Ifng; Ifg; IFN-g
Purity
>75% as determined by SDS-PAGE
Pricing
Application Data
COVID 19 (BA.2.75) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258580)
Full Name
SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein (ECD, His Tag)
Purity
>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized ACE2 Protein, Human, Recombinant (mFc Tag)(Cat:10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2(BA.4/BA.5) S1+S2 trimer Protein (ECD, His & AVI Tag) (Cat:AAA258581), the EC50 is 2.7-8.1 ng/mL.)
COVID 19 (BA.4/BA.5) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258581)
Full Name
SARS-CoV-2 (BA.4/BA.5) Spike S1+S2 trimer Protein (ECD, His & AVI Tag), Biotinylated
Purity
>90% as determined by SDS-PAGE. >90% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.75.2) Spike RBD Protein (His Tag)(Cat: AAA258583), the EC50 is 20-60 ng/mL.)
COVID 19 BA.2.75.2 (Omicron) Spike RBD Coronavirus, Active Protein (Cat# AAA258583)
Full Name
SARS-CoV-2 BA.2.75.2 (Omicron) Spike RBD Protein (His Tag)
Purity
>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.75)Spike RBD Protein (His&AVI Tag),Biotinylated(Cat: AAA258584), the EC50 is 1.8-6 ng/mL.)
COVID 19 BA.2.75 (Omicron) Spike RBD Coronavirus, Active Protein (Cat# AAA258584)
Full Name
SARS-CoV-2 BA.2.75 (Omicron) Spike RBD Protein (His & AVI Tag), Biotinylated
Purity
>90% as determined by SDS-PAGE. >90% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein(ECD, His&AVI Tag)(Cat: AAA258587), the EC50 is 4-12 ng/mL.)
COVID 19 (BA.2.75) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258587)
Full Name
SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein (ECD, His & AVI Tag), Biotinylated
Purity
>90% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant Recombinant SARS-CoV-2 (BA.2.3.20) Spike RBD Protein (His Tag)(Cat: AAA258589), the EC50 is 6-18 ng/mL.)
COVID 19 (BA.2.3.20) Spike RBD Coronavirus, Active Protein (Cat# AAA258589)
Full Name
SARS-CoV-2 (BA.2.3.20) Spike RBD Protein (His Tag)
Purity
>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 BA.3 (Omicron) Spike S1+S2 trimer Protein (His Tag)(Cat:AAA258595), the EC50 is 5-15 ng/mL.)
COVID 19 BA.3 (Omicron) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258595)
Full Name
SARS-CoV-2 BA.3 (Omicron) Spike S1+S2 trimer Protein (ECD, His Tag)
Purity
>90% as determined by SDS-PAGE. >90% as determined by SEC-HPLC.
Pricing
Bioactivity
Angiotensin-converting enzyme 2 (ACE2), Active Protein (Cat# AAA244035)
Full Name
Recombinant Human Angiotensin-converting enzyme 2 (ACE2), partial
Gene Names
ACE2; ACEH
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Bioactivity
(Carbonic Anhydrase (CA) catalyzes the reversible reaction of CO2 H2O = HCO3- H, which is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. CA13 is a cytosolic enzyme with a unique and widespread distribution pattern as compared to the other cytosolic CAs, indicating that it may play important physiological roles in several organs. The activity of recombinant mouse CA13 was measured by its ability to hydrolyze 4-Nitrophenyl acetate (4-NPA) to 4-Nitrophenol. The reaction was performed in 12.5 mM Tris, 75 mM NaCl, pH 7.5 (assay buffer), initiated by addition 50 uL of various concentrations of CA13 (diluted by assay buffer) to 50 uL of 2 mM substrate 4-NPA (100 mM stock in Acetone, diluted by assay buffer). Incubated at 37 degree C for 5min, then read at a wavelength of 400 nm.)
Carbonic Anhydrase XIII (CA13), Active Protein (Cat# AAA161907)
Full Name
Active Carbonic Anhydrase XIII (CA13)
Gene Names
Car13; Ca13; 2310075C21Rik
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with FBLN2.)
Fibulin 2 (FBLN2), Active Protein (Cat# AAA161909)
Full Name
Active Fibulin 2 (FBLN2)
Gene Names
Fbln2; FIBL-2; 5730577E14Rik
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Taste receptor type 1 member 3 (TAS1R3), responsible for mediating taste perception, is a G protein-coupled receptor (GPCR) expressed in gustatory cells located within the taste buds on the tongue. It can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human TAS1R3 and recombinant mouse TAS1R1. Briefly, biotin-linked TAS1R3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to TAS1R1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of recombinant human TAS1R3 and recombinant mouse TAS1R1 was shown in Figure 1, the EC50 for this effect is 0.31 ug/mL.)
Taste Receptor Type 1 Member 3 (TAS1R3), Active Protein (Cat# AAA161923)
Full Name
Active Taste Receptor Type 1 Member 3 (TAS1R3)
Gene Names
TAS1R3; T1R3
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.