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AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1400-1450 of 2875 product results
Application Data
(Immobilized mouse ALCAM-His at 10 ug/ml (100 ul/well) can bind mouse CD6-Fc, The EC50 of mouse CD6-Fc is 0.08-0.18 ug/ml.)
CD166/ALCAM, Active Protein (Cat# AAA258115)
Full Name
CD166/ALCAM Protein, Mouse, Recombinant (His Tag)
Gene Names
Alcam; BEN; SC1; MuSC; CD166; AI853494; DM-GRASP
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.015-0.06 ug/mL.)
Cardiotrophin 1, Active Protein (Cat# AAA258040)
Full Name
Cardiotrophin 1 Protein, Human, Recombinant (hFc Tag)
Gene Names
CTF1; CT1; CT-1
Purity
>80% as determined by SDS-PAGE
Pricing
Application Data
RANKL, Active Protein (Cat# AAA258585)
Full Name
Human RANKL Protein (ECD, rFc Tag)
Gene Names
TNFSF11; ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2
Purity
>95% as determined by SDS-PAGE. >90% as determined by SEC-HPLC.
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 BA.2.75.2(Omicron)Spike S1+S2 trimer Protein(ECD,His Tag)(Cat: AAA258590), the EC50 is 5-15 ng/mL.)
COVID 19 BA.2.75.2 (Omicron) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258590)
Full Name
SARS-CoV-2 BA.2.75.2 (Omicron) Spike S1+S2 trimer Protein (ECD, His Tag)
Purity
>90% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL7 in V- bottom shaped 96-well microtiter plate.)
Galectin 7 (GAL7), Active Protein (Cat# AAA153020)
Full Name
Active Galectin 7 (GAL7)
Gene Names
LGALS7B; PI7; GAL7; Gal-7; HKL-14; LGALS7
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Fibroblast growth factor 13 (FGF13) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. Besides, Prion Protein (PRNP) has been identified as an interactor of FGF13, thus a binding ELISA assay was conducted to detect the interaction of recombinant human FGF13 and recombinant human PRNP. Briefly, FGF13 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to PRNP-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-FGF13 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of FGF13 and PRNP was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of FGF13 with PRNP.)
Fibroblast Growth Factor 13, Active Protein (Cat# AAA150128)
Full Name
Active Fibroblast Growth Factor 13 (FGF13)
Gene Names
FGF13; FGF2; FHF2; FHF-2; FGF-13; LINC00889
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Bioactivity
(Figure. The binding activity of PRKG2 with HSP90aA1.Protein Kinase, cGMP Dependent Type II (PRKG2) belong to cGMP-dependent protein kinase or Protein Kinase G (PKG) which is a serine/threonine-specific protein kinase that is activated by cGMP. Two PKG genes, coding for PKG type I (PKG-I) and type II (PKG-II), have been identified in mammals. The PKG-I and PKG-II are homodimers of two identical subunits (~75kDa and ~85kDa, respectively) and share common structural features. PKG phosphorylates a number of biologically important targets and is implicated in the regulation of smooth muscle relaxation, platelet function, sperm metabolism, cell division, and nucleic acid synthesis. Besides, Heat Shock Protein 90kDa Alpha A1 (HSP90aA1) has been identified as an interactor of PRKG2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PRKG2 and recombinant human HSP90aA1. Briefly, PRKG2 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to HSP90aA1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-PRKG2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PRKG2 and HSP90aA1 was shown in Figure 1, and this effect was in a dose dependent manner.)
Protein Kinase, cGMP Dependent Type II, Active Protein (Cat# AAA150142)
Full Name
Active Protein Kinase, cGMP Dependent Type II (PRKG2)
Gene Names
PRKG2; PKG2; cGK2; cGKII; PRKGR2
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Bioactivity
(Glutathione S-Transferases (GSTs) are members of the phase II detoxification enzyme family that conjugate glutathione to various electrophilic compounds, including metabolites generated by oxidative processes in the body, environmental toxins or carcinogens, and anti-cancer drugs. GSTM1 is a cytosolic protein that belongs to the mu class of the GST superfamily. GSTM1 catalyze the endogenous glutathione conjugation 1-Chloro-2,4-dinitrobenzene (CDNB), which can increase in the absorbance at 340 nm. The reaction was performed in adding 10 ul 200 mM glutathione (reduced) and 10 ul 100 mM CDNB in 980 ul 100 mM NaH2PO4 (pH7.0), rapidly mixed. Then add 50 ul mixed substrates to 50 ul different concentrations of recombinant human GSTM1, mix gently. Incubated at 37 degree C for 5min, then read at a wavelength of 340 nm. The specific activity of recombinant human GSTM1 is >330,000 pmol/min/ug.)
Glutathione S Transferase Mu 1 (GSTM1), Active Protein (Cat# AAA161760)
Full Name
Active Glutathione S Transferase Mu 1 (GSTM1)
Gene Names
GSTM1; MU; H-B; GST1; GTH4; GTM1; MU-1; GSTM1-1; GSTM1a-1a; GSTM1b-1b
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Glutathione S-Transferases (GSTs) are members of the phase II detoxification enzyme family that conjugate glutathione to various electrophilic compounds, including metabolites generated by oxidative processes in the body, environmental toxins or carcinogens, and anti-cancer drugs. GSTM1 is a cytosolic protein that belongs to the mu class of the GST superfamily. GSTM1 catalyze the endogenous glutathione conjugation 1-Chloro-2,4-dinitrobenzene (CDNB), which can increase in the absorbance at 340 nm. The reaction was performed in adding 10 ul 200 mM glutathione (reduced) and 10 ul 100 mM CDNB in 980 ul 100 mM NaH2PO4 (pH7.0), rapidly mixed. Then add 50 ul mixed substrates to 50 ul different concentrations of recombinant mouse GSTM1, mix gently. Incubated at 37 degree C for 5min, then read at a wavelength of 340 nm. The specific activity of recombinant mouse GSTM1 is >14000 pmol/min/ug.)
Glutathione S Transferase Mu 1 (GSTM1), Active Protein (Cat# AAA161761)
Full Name
Active Glutathione S Transferase Mu 1 (GSTM1)
Gene Names
Gstm1; Gstb1; Gstb-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Macrophage Colony Stimulating Factor (M-CSF), also known as CSF-1, is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. It can also affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human M-CSF and recombinant human Colony Stimulating Factor 2 Receptor Alpha (CSF2Ra). Briefly, biotin-linked M-CSF were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to CSF2Ra-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human M-CSF and recombinant human CSF2Ra was shown in Figure 1, the EC50 for this effect is 0.02 ug/mL.)
Colony Stimulating Factor 1, Macrophage (MCSF), Active Protein (Cat# AAA161683)
Full Name
Active Colony Stimulating Factor 1, Macrophage (MCSF)
Gene Names
CSF1; MCSF; CSF-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit recombinant rmWnt3a induced alkaline phosphatase production by C3H10T 1/2 cells. The ED50 for this effect is 0.05-0.3 ug/mL.)
DKK1, Active Protein (Cat# AAA258244)
Full Name
DKK1 Protein, Mouse, Recombinant (His Tag)
Gene Names
Dkk1; mdkk-1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human EphB4-his at 2 ug/ml (100 ul/well) can bind human EphrinB2 Fc chimera with a linear range of 1-25 ng/ml.)
Ephrin B2, Active Protein (Cat# AAA257941)
Full Name
Ephrin B2 Protein, Human, Recombinant (His & hFc Tag)
Gene Names
EFNB2; HTKL; EPLG5; Htk-L; LERK5
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(1. Immobilized Human ERBB3 His at 2 ug/ml (100 ul/well) can bind Human NRG1 Fc, the EC50 of Human NRG1 Fc is 8-40 ng/mL. 2. Immobilized Rhesus ERBB3 His at 2 ug/ml (100 ul/well) can bind Human NRG1 Fc, the EC50 of Human NRG1 Fc is 20-80 ng/mL.)
NRG1 Beta 1, Active Protein (Cat# AAA257981)
Full Name
NRG1 Beta 1 Protein, Human, Recombinant (ECD, Fc Tag)
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131
Purity
>85% as determined by SDS-PAGE
Pricing
SDS-PAGE
RAGE, Active Protein (Cat# AAA257986)
Full Name
RAGE Protein, Human, Recombinant (His Tag)
Gene Names
AGER; RAGE; SCARJ1
Purity
>98% as determined by SDS-PAGE
Pricing
Bioactivity
(HTRF assay for TSSK2 activity 1 uM STK S1 substrate was incubated with different concentrations of TSSK2 protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 10 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Bioactivity
(Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide r)
Superoxide Dismutase 1 (SOD1), Active Protein (Cat# AAA153107)
Full Name
Active Superoxide Dismutase 1 (SOD1)
Gene Names
Sod1; Ipo1; SODC; Ipo-1; Sod-1; CuZnSOD; Cu/Zn-SOD; MGC107553; B430204E11Rik; Sod1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure. The binding activity of GaNAB with MYC)
Glucosidase Alpha, Neutral AB, Active Protein (Cat# AAA150131)
Full Name
Active Glucosidase Alpha, Neutral AB (GaNAB)
Gene Names
GANAB; G2AN; GIIA; PKD3; GLUII
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
SDS-PAGE
NME3, Active Protein (Cat# AAA48925)
Full Name
NME3, 22-169aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
NME3; NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Application Data
(Human G-CSF stimulates cell proliferation of the M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range )
G-CSF, Active Protein (Cat# AAA48456)
Full Name
G-CSF, 31-204 aa, Human, E Coli (Bioactivity Validated)
Gene Names
CSF3; GCSF; CSF3OS; C17orf33
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Bioactivity
(Glypican 5 (GPC5) belongs to the glypican family of proteoglycans that are linked to the cell surface through a glycosyl-phosphatidylinositol anchor. GPC5 is expressed primarily in embryonic neurons and mesenchyme and it is implicated in a variety of physiological processes, ranging from cell proliferation to morphogenesis. Besides, Syndecan 1 (SDC1) has been identified as an interactor of GPC5, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant rat GPC5 and recombinant human SDC1. Briefly, GPC5 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to SDC1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-GPC5 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant rat GPC5 and recombinant human SDC1 was shown in Figure 1, the EC50 for this effect is 0.6 ug/mL.)
Glypican 5 (GPC5), Active Protein (Cat# AAA161913)
Full Name
Active Glypican 5 (GPC5)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 3 receptor alpha (IL3Ra), also known as CD123 (Cluster of Differentiation 123), is a subunit of the functional high-affinity mouse IL-3 receptor which is a heterodimer. The alpha subunit alone binds IL-3 with low affinity. The beta subunit doe)
Interleukin 3 Receptor Alpha (IL3Ra), Active Protein (Cat# AAA153091)
Full Name
Active Interleukin 3 Receptor Alpha (IL3Ra)
Gene Names
Il3ra; CD123; SUT-1; CDw123
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Glypican 4 (GPC4) is a cell surface heparan sulfate proteoglycans which composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Besides, Fibroblast Growth Factor 2, Basic (FGF2) has been identified as an interactor of GPC4, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant rat GPC4 and recombinant human FGF2. Briefly, GPC4 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FGF2-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-GPC4 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450 nm immediately. The binding activity of recombinant rat GPC4 and recombinant human FGF2 was shown in Figure 1, the EC50 for this effect is 2.64 ug/mL.)
Glypican 4 (GPC4), Active Protein (Cat# AAA161822)
Full Name
Active Glypican 4 (GPC4)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Measured by its binding ability in a functional ELISA. Immobilized Mouse Ttr at 5 ?g/ml can bind Mouse Rbp4, the EC50 is 17.06-26.23 ng/mL.)
Transthyretin (Ttr), Active Protein (Cat# AAA279232)
Full Name
Recombinant Mouse Transthyretin (Ttr)(Active)
Gene Names
Ttr; D17860; AA408768; AI787086; prealbumin
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human 2B4 at 2 ug/ml (100 ul/well) can bind human CD48. The EC50 of human CD48 is 0.39 ug/ml.)
2B4/CD244, Active Protein (Cat# AAA257820)
Full Name
2B4/CD244 Protein, Human, Recombinant (His Tag)
Gene Names
CD244; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized human His-NKG2D (78-216) at 2 ug/ml (100 ul/well) can bind human ULBP1-Fch, The EC50 of human ULBP1-Fch is 8-24 ng/mL.)
ULBP1, Active Protein (Cat# AAA257907)
Full Name
ULBP1 Protein, Human, Recombinant (His & hFc Tag)
Gene Names
ULBP1; RAET1I
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(The purity of 2019-nCoV Spike S is greater than 95% as determined by SEC-HPLC.)
COVID 19 Spike S Trimer Coronavirus, Active Protein (Cat# AAA76122)
Full Name
SARS COV2 Spike protein S Trimer Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
VEGF164, Active Protein (Cat# AAA79287)
Full Name
Mouse VEGF164
Gene Names
Vegfa; Vpf; Vegf
Reactivity
Mouse
Purity
> 95% by SDS-PAGE & silver stain
Pricing
gamma-Glutamyl Transferase, Active Protein (Cat# AAA44875)
Full Name
gamma-Glutamyl Transferase Bovine Kidney
Pricing
Bioactivity
(Peptidoglycan is coated at 10 ug/ml (100 ul/well) can bind Human PGLYRP1. The ED50 range )
PGLYRP1/PGRP-S, Active Protein (Cat# AAA48403)
Full Name
Recombinant human PGLYRP1/PGRP-S protein
Gene Names
PGLYRP1; PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 37, also known as Interleukin 1 Zeta (IL1z), is an anti-inflammatory cytokine. Interleukines are cytokines that make an important part of immune signaling. It belongs to the interleukin-1 family. IL-37 plays a role in protecting the body again)
Interleukin 1 Zeta (IL1z), Active Protein (Cat# AAA153127)
Full Name
Active Interleukin 1 Zeta (IL1z)
Gene Names
IL37; FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
SDS-PAGE
Interferon omega-1 protein (IFNW1), Active Protein (Cat# AAA114245)
Full Name
Recombinant Human Interferon omega-1 protein (IFNW1) (Active)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
Protein Kinase R (PKR), Active Protein (Cat# AAA148174)
Full Name
Active Protein Kinase R (PKR)
Gene Names
EIF2AK2; PKR; PRKR; EIF2AK1; PPP1R83
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 80%
Pricing
WB (Western Blot)
(Figure 3. Western BlotSample: Recombinant CTSV, Human;Antibody: Rabbit Anti-Human CTSV Ab)
Cathepsin V (CTSV), Active Protein (Cat# AAA148206)
Full Name
Active Cathepsin V (CTSV)
Gene Names
CTSV; CTSU; CATL2; CTSL2
Reactivity
Homo sapiens (Human)
Applications
Activity Assay
Purity
>95%
Pricing
SDS-PAGE
COVID 19 Spike Protein (RBD) Coronavirus, Active Protein (Cat# AAA176995)
Full Name
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing
Application Data
(Immobilized ACE2 Protein, Human, Recombinant (mFc Tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD(E484K)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD(E484K)-His is 7-42ng/mL.)
COVID 19 Spike RBD(E484K)-His Coronavirus, Active Protein (Cat# AAA258105)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD(E484K)-His Recombinant Protein
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.5-3 ug/mL in the presence of 200 ng/mL recombinant human Fas ligand.)
DcR3, Active Protein (Cat# AAA257848)
Full Name
DcR3 Protein, Human, Recombinant (hFc Tag)
Gene Names
TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1
Purity
>85% as determined by SDS-PAGE
Pricing
SDS-PAGE
(Sample: Active recombinant GNLY, Human)
Granulysin (GNLY), Active Protein (Cat# AAA153093)
Full Name
Active Granulysin (GNLY)
Gene Names
GNLY; 519; LAG2; NKG5; LAG-2; D2S69E; TLA519
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>80%
Pricing
Bioactivity
(Figure. The binding activity of IL4 with IL4R.)
Interleukin 4, Active Protein (Cat# AAA150061)
Full Name
Active Interleukin 4 (IL4)
Gene Names
Il4; Il4e12
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Application Data
V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC), Active Protein (Cat# AAA148128)
Full Name
Active V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC)
Gene Names
MYC; MRTL; MYCC; c-Myc; bHLHe39
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
WB (Western Blot)
(Sample: Recombinant PON1, Human;Antibody: Rabbit Anti-Human PON1 Ab)
Paraoxonase 1 (PON1), Active Protein (Cat# AAA147871)
Full Name
Active Paraoxonase 1 (PON1)
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
ELISA
(SARS COV2 S B.1.1.529 trimer ACE functional binding ELISA assay2019-ncov S B.1.1.529 trimer(coating at 0.1ug-well) binding with Human ACE2-Fc.The linear range was found to be 23 ng/ml)
SARS COV2 Spike protein S B.1.1.529 (omicron) Trimer, Active Protein (Cat# AAA76382)
Full Name
SARS COV2 Spike protein S B.1.1.529 (omicron) Trimer Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Application Data
(Effects of ACM from Olig2PC-Astros and NPC-Astros on neurons.(h and i) RT-PCR analysis of the expression of the antioxidant defense-related genes, GCLC and NFE2L2 (n=3), and the neurotrophic growth factor genes, BDNF, GDNF and NT-3 (n=3).)
Glial-Derived Neurotrophic Factor, Active Protein (Cat# AAA76397)
Full Name
Mouse Glial-Derived Neurotrophic Factor Recombinant
Gene Names
Gdnf; AI385739
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
SDS-PAGE
FKBP1a /FKBP12, Active Protein (Cat# AAA48496)
Full Name
FKBP1a /FKBP12, 1-108aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
FKBP1A; FKBP1; PKC12; PKCI2; FKBP12; PPIASE; FKBP-12; FKBP-1A
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Application Data
G-CSF (CSF3), Active Protein (Cat# AAA214220)
Full Name
Recombinant Human G-CSF (CSF3)
Gene Names
CSF3; GCSF; CSF3OS; C17orf33
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized human GST-SerpinB2 at 10 ug/ml (100 ul/well) can bind biotinylated human uPA-His, The EC50 of biotinylated human uPA-His is 10.24-23.88 ng/ml.)
SerpinB2, Active Protein (Cat# AAA257905)
Full Name
SerpinB2 Protein, Human, Recombinant (GST Tag)
Gene Names
SERPINB2; PAI; PAI2; PAI-2; PLANH2; HsT1201
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells.The ED50 for this effect is 3-9 ug/mL.)
NBL1, Active Protein (Cat# AAA258216)
Full Name
NBL1 Protein, Mouse, Recombinant (His Tag)
Gene Names
Nbl1; DAN; NO3; Dana; D4H1S1733E
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA3-His at 10 ug/mL (100 uL/well) can bind mouse EFNA5-Fc. The EC50 of mouse EFNA5-Fc is 4.9-11.4 ng/mL.)
EphA3, Active Protein (Cat# AAA258235)
Full Name
EphA3 Protein, Mouse, Recombinant (His Tag)
Gene Names
Epha3; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4; AW492086
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit the human CSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.4-1.6ug/mL in the presence of 3 ng/ml Recombinant Human M-CSF.)
CSF1R, Active Protein (Cat# AAA257833)
Full Name
CSF1R Protein, Human, Recombinant (mFc Tag)
Gene Names
CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF), Active Protein (Cat# AAA146598)
Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)
Gene Names
CSF2; GMCSF
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Bioactivity
(Leukemia inhibitory factor (LIF), is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. LIF as a cytokine also has another fuction including: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. Besides, Colony Stimulating Factor Receptor, Granulocyte (GCSFR) has been identified as an interactor of LIF, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse LIF and recombinant mouse GCSFR. Briefly, LIF were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to GCSFR-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-LIF pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of LIF and GCSFR was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of LIF with GCSFR.)
Leukemia Inhibitory Factor, Active Protein (Cat# AAA150066)
Full Name
Active Leukemia Inhibitory Factor (LIF)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.