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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 1400-1450 of 2583 product results


product-image-AAA257820_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human 2B4 at 2 ug/ml (100 ul/well) can bind human CD48. The EC50 of human CD48 is 0.39 ug/ml.)

2B4/CD244, Active Protein (Cat# AAA257820)

Full Name
2B4/CD244 Protein, Human, Recombinant (His Tag)
Gene Names
CD244; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257821_AD13.png Application Data (Immobilized human TrKc-Fch at 10 ug/ml (100 ul/well) can bind biotinylated human NT3, The EC50 of biotinylated human NT3 is 23.4-54.6 ng/ml.)

TrkC, Active Protein (Cat# AAA257821)

Full Name
TrkC Protein, Human, Recombinant (His & hFc Tag)
Gene Names
NTRK3; TRKC; gp145(trkC)
Purity
>98% as determined by SDS-PAGE
Pricing
product-image-AAA257822_AD13.png Application Data (Immobilized human Trkc-His at 10 ug/ml (100 ul/well) can bind biotinylated human NT3, The EC50 of biotinylated human NT3 is 0.03-0.07 ug/ml.)

TrkC, Active Protein (Cat# AAA257822)

Full Name
TrkC Protein, Human, Recombinant (His Tag)
Gene Names
NTRK3; TRKC; gp145(trkC)
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257828_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized FGF2 Protein, Human at 2 ug/mL (100 uL/well) can bind Glypican 3 Protein, Human, Recombinant (495S/A, hFc Tag), the EC50 of Glypican 3 is 0.75-1.1 ug/mL.)

Glypican 3, Active Protein (Cat# AAA257828)

Full Name
Glypican 3 Protein, Human, Recombinant (495S/A, hFc Tag)
Gene Names
GPC3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257831_AD13.png Application Data (Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). (Conn, G. et al.,1990, Proc. Natl. Acad. Sci. USA 87:1323.) The ED50 for this effect is typically 10-40 ng/mL in the presence of 10 ng/mL human VEGF165.)

FLT1, Active Protein (Cat# AAA257831)

Full Name
FLT1 Protein, Human, Recombinant (His Tag)
Gene Names
FLT1; FLT; FLT-1; VEGFR1; VEGFR-1
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257838_AD13.png Application Data (Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 4-20 ug/mL in the presence of 500 ng/mL recombinant human BMP2.)

DLL4, Active Protein (Cat# AAA257838)

Full Name
DLL4 Protein, Human, Recombinant
Gene Names
DLL4; AOS6; delta4; hdelta2
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257842_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human BCL2-His at 10 ug/ml (100 ul/well) can bind biotinylated mouse BCL2L1-His, The EC50 of biotinylated mouse BCL2L1-His is 0.07-0.15 ug/ml.)

Bcl-2, Active Protein (Cat# AAA257842)

Full Name
Bcl-2 Protein, Human, Recombinant (His Tag)
Gene Names
BCL2; Bcl-2; PPP1R50
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257844_AD13.png Application Data (Measure by its ability to bind with human NRG1-beta1 in a functional ELISA.)

HER3/ERBB3, Active Protein (Cat# AAA257844)

Full Name
HER3/ERBB3 Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257847_AD13.png Application Data (Immobilized Human Leptin at 2 ug/mL (100 uL/well) can bind Human Leptin Receptor (His & hFc Tag), the EC50 of Human Leptin Receptor (His & hFc Tag) is 70-420 ng/mL.)

Leptin, Active Protein (Cat# AAA257847)

Full Name
Leptin Protein, Human, Recombinant
Gene Names
LEP; OB; OBS; LEPD
Purity
>98% as determined by SDS-PAGE
Pricing
product-image-AAA257859_AD13.png Application Data (Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 10-60 ng/mL.)

FGF9, Active Protein (Cat# AAA257859)

Full Name
FGF9 Protein, Human, Recombinant (hFc Tag)
Gene Names
FGF9; GAF; FGF-9; SYNS3; HBFG-9; HBGF-9
Purity
>85%, as determined by SDS-PAGE
Pricing
product-image-AAA257860_AD13.png Application Data (Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 0.1-0.6 ug/mL in the presence of 50 ng/mL of hBMP4.)

Noggin/NOG, Active Protein (Cat# AAA257860)

Full Name
Noggin/NOG Protein, Human, Recombinant (hFc Tag)
Gene Names
NOG; SYM1; SYNS1; SYNS1A
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257864_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human PTN at 10 ug/ml (100 ul/well) can bind rat SDC1-Fc, The EC50 of rat SDC1-Fc is 0.35-0.81 ug/ml.)

Pleiotrophin/PTN, Active Protein (Cat# AAA257864)

Full Name
Pleiotrophin/PTN Protein, Human, Recombinant
Gene Names
PTN; HARP; HBNF; HBGF8; NEGF1
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257865_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human PD1-His at 10 ug/mL (100 uL/well) can bind human PDCD1LG2-Fc. The EC50 of PDCD1LG2-Fc is 0.05-0.12 ug/mL.)

PD-L2, Active Protein (Cat# AAA257865)

Full Name
PD-L2 Protein, Human, Recombinant (hFc Tag)
Gene Names
PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257869_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human Leptin at 1.25 ug/ml (100 ul/well) can bind human Leptin receptor with a linear range of 0.032-4 ug/ml.)

Leptin Receptor, Active Protein (Cat# AAA257869)

Full Name
Leptin Receptor Protein, Human, Recombinant (His & hFc Tag)
Gene Names
LEPR; OBR; OB-R; CD295; LEP-R; LEPRD
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257876_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized TGFBR2h (1-166Q) at 10 ug/mL (100 uL/well) can bind TGFB1-His/Biotin, the EC50 of human TGFB1-His/Biotin is 0.50-1.20 ug/mL.)

TGFBR2, Active Protein (Cat# AAA257876)

Full Name
TGFBR2 Protein, Human, Recombinant (ECD, His Tag)
Gene Names
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257882_AD13.png Application Data (Immobilized Cynomolgus mFc-TNFSF12 at 10 ug/ml (100 ul/well) can bind human Fc-TNFRSF12A, The ED50 of human Fc-TNFRSF12A is 0.07-0.15 ug/ml.)

TWEAKR, Active Protein (Cat# AAA257882)

Full Name
TWEAKR Protein, Human, Recombinant (hFc Tag)
Gene Names
TNFRSF12A; FN14; CD266; TWEAKR
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257884_AD13.png Application Data (Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 1-5 ng/mL.)

SCF, Active Protein (Cat# AAA257884)

Full Name
SCF Protein, Human, Recombinant (aa 1-189, His Tag)
Gene Names
KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7
Purity
>92% as determined by SDS-PAGE
Pricing
product-image-AAA257887_AD13.png Application Data (Measured by its ability to inhibit rhBMP4-induced alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 2-8 ug/mL in the presence of 50 ng/mL of recombinant human BMP4.)

BMPRIB, Active Protein (Cat# AAA257887)

Full Name
BMPRIB Protein, Human, Recombinant (hFc Tag)
Gene Names
BMPR1B; ALK6; AMDD; BDA2; ALK-6; BDA1D; CDw293
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257906_AD13.png Application Data (Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-8 ug/mL.)

Epiregulin, Active Protein (Cat# AAA257906)

Full Name
Epiregulin Protein, Human, Recombinant (hFc Tag)
Gene Names
EREG; ER; Ep; EPR
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257907_AD13.png Application Data (Immobilized human His-NKG2D (78-216) at 2 ug/ml (100 ul/well) can bind human ULBP1-Fch, The EC50 of human ULBP1-Fch is 8-24 ng/mL.)

ULBP1, Active Protein (Cat# AAA257907)

Full Name
ULBP1 Protein, Human, Recombinant (His & hFc Tag)
Gene Names
ULBP1; RAET1I
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257908_AD13.png Application Data (Immobilized human ulBP1-His at 10 ug/ml (100 ul/well) can bind human S4-Fc3L3-NKG2D, The EC50 of human S4-Fc3L3-NKG2D is 0.39-0.91 ug/ml.)

ULBP1, Active Protein (Cat# AAA257908)

Full Name
ULBP1 Protein, Human, Recombinant (His Tag)
Gene Names
ULBP1; RAET1I
Purity
>98% as determined by SDS-PAGE
Pricing
product-image-AAA257911_AD11.jpg Application Data (Loaded Fc-DPPIV on ProA Biosensor, can bind MERS-CoV Spike/S1 Protein (S1 Subunit, aa 1-725, His Tag) with an affinity constant of 0.02 nM as determined by Octet RED System.)

DPP4/CD26, Active Protein (Cat# AAA257911)

Full Name
DPP4/CD26 Protein, Human, Recombinant (hFc Tag)
Gene Names
DPP4; CD26; ADABP; ADCP2; DPPIV; TP103
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257923_AD13.png Application Data (Measured by its ability to inhibit IL-2 secretion in human T lymphocytes induced by anti-CD3 antibody and anti-CD28 antibody. The ED50 for this effect is 0.7-3.5 ug/mL.)

B7-H4, Active Protein (Cat# AAA257923)

Full Name
B7-H4 Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
VTCN1; B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257928_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human 2B4-His, at 10 ug/mL (100 uL/well) can bind human CD48-Fc. The EC50 of human CD48-Fc is 0.03-0.06 ug/mL.)

CD48, Active Protein (Cat# AAA257928)

Full Name
CD48 Protein, Human, Recombinant (hFc Tag)
Gene Names
CD48; BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257932_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human CEACAM6-his at 10 ug/mL (100 ul/well) can bind biotinylated human CEACAM8-his, The EC50 of biotinylated human CEACAM8-his is 0.17 ug/mL.)

CEACAM6, Active Protein (Cat# AAA257932)

Full Name
CEACAM6 Protein, Human, Recombinant (His Tag)
Gene Names
CEACAM6; NCA; CEAL; CD66c
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA146603_AD10.jpg Application Data

Interferon Gamma (IFNg), Active Protein (Cat# AAA146603)

Full Name
Active Interferon Gamma (IFNg)
Gene Names
Ifng; IFNG2
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146609_AD8.jpg Application Data

Interleukin 6 (IL6), Active Protein (Cat# AAA146609)

Full Name
Active Interleukin 6 (IL6)
Gene Names
IL6; IL-6; CHIL-6; interleukin-6
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA146621_WB8.jpg WB (Western Blot) (Western BlotSample: Recombinant OPN, Human;Antibody: Rabbit Anti-Human OPN Ab)

Osteopontin (OPN), Active Protein (Cat# AAA146621)

Full Name
Active Osteopontin (OPN)
Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Reactivity
Homo sapiens (Human)
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA149253_SDS_PAGE13.jpg SDS-PAGE

Annexin A2 (ANXA2), Active Protein (Cat# AAA149253)

Full Name
Active Annexin A2 (ANXA2)
Gene Names
Anxa2; Cal1h; AW215814
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148168_WB8.jpg WB (Western Blot) (Sample: Recombinant AMH, Human;Antibody: Rabbit Anti-Human AMH Ab)

Anti-Mullerian Hormone (AMH), Active Protein (Cat# AAA148168)

Full Name
Active Anti-Mullerian Hormone (AMH)
Gene Names
AMH; MIF; MIS
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA148187_AD11.jpg Application Data

Arginase (ARG), Active Protein (Cat# AAA148187)

Full Name
Active Arginase (ARG)
Reactivity
Rat
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148210_AD8.jpg Application Data

Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1), Active Protein (Cat# AAA148210)

Full Name
Active Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1)
Gene Names
ALDH1A1; ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA148214_AD11.jpg Application Data

Arylsulfatase B (ARSB), Active Protein (Cat# AAA148214)

Full Name
Active Arylsulfatase B (ARSB)
Gene Names
ARSB; ASB; G4S; MPS6
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 80%
Pricing
product-image-AAA148215_AD11.jpg Application Data

Arylsulfatase F (ARSF), Active Protein (Cat# AAA148215)

Full Name
Active Arylsulfatase F (ARSF)
Gene Names
ARSF; ASF
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA150054_BIOACTIVITY10.jpg Bioactivity (Figure. Cell proliferation of MCF-7 cells after stimulated with IGF1.)

Insulin Like Growth Factor 1, Active Protein (Cat# AAA150054)

Full Name
Active Insulin Like Growth Factor 1 (IGF1)
Gene Names
Igf1; Igf-1; Igf-I; C730016P09Rik
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150066_BIOACTIVITY11.png Bioactivity (Leukemia inhibitory factor (LIF), is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. LIF as a cytokine also has another fuction including: the growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. Besides, Colony Stimulating Factor Receptor, Granulocyte (GCSFR) has been identified as an interactor of LIF, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse LIF and recombinant mouse GCSFR. Briefly, LIF were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to GCSFR-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-LIF pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of LIF and GCSFR was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of LIF with GCSFR.)

Leukemia Inhibitory Factor, Active Protein (Cat# AAA150066)

Full Name
Active Leukemia Inhibitory Factor (LIF)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150086_BIOACTIVITY10.png Bioactivity (IL-1RA is an agent that binds non-productively to the cell surface interleukin-1 receptor (IL-1R), the same receptor that binds interleukin 1 (IL-1), preventing IL-1 from sending a signal to that cell. Besides, Interleukin 1 Alpha (IL-1a) has been identified as an interactor of IL-1RA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human IL-1RA and recombinant human IL-1a. Briefly, IL1RA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to IL-1a-coated microtiter wells and incubated for 2 h at 37. Wells were washed with PBST and incubated for 1 h with anti-IL-1RA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IL-1RA and IL-1a was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of IL-1RA with IL-1a.)

Interleukin 1 Receptor Antagonist, Active Protein (Cat# AAA150086)

Full Name
Active Interleukin 1 Receptor Antagonist (IL1RA)
Gene Names
IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150139_BIOACTIVITY10.png Bioactivity (Sirtuin 4, also known as SIRT4, is a member of the sirtuin family. SIRT4 is a mitochondrial ADP-ribosyltransferase that inhibits mitochondrial glutamate dehydrogenase 1 activity, thereby downregulating insulin secretion in response to amino acids. It has been shown that SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells. Besides, Heat Shock 60kD Protein 1, Chaperonin (HSPD1) has been identified as an interactor of SIRT4, thus a binding ELISA assay was conducted to detect the interaction of recombinant human SIRT4 and recombinant human HSPD1. Briefly, SIRT4 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to HSPD1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-SIRT4 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of SIRT4 and HSPD1 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of SIRT4 with HSPD1)

Sirtuin 4, Active Protein (Cat# AAA150139)

Full Name
Active Sirtuin 4 (SIRT4)
Gene Names
SIRT4; SIR2L4
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA214335_AD13.png Application Data

IFNG, Active Protein (Cat# AAA214335)

Full Name
Recombinant Rat IFNG
Gene Names
Ifng; IFNG2
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214323_AD13.png Application Data

IL25, Active Protein (Cat# AAA214323)

Full Name
Recombinant Mouse IL25
Gene Names
Il25; Il17e; IL-17e
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA150975_SEQUENCE10.jpg Sequence

Vimentin (VIM), Active Protein (Cat# AAA150975)

Full Name
Active Vimentin (VIM)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA152231_BIOACTIVITY11.jpg Bioactivity (Interferon Beta (IFNb) is belongs to type I interferons (IFNs) family which a large subgroup of interferon proteins that help regulate the activity of the immune system. The IFNb proteins are produced in large quantities by fibroblasts. They have antiviral activity that is involved mainly in innate immune response. Two types of IFNb have been described, IFNb1 (IFNB1) and IFNb3 (IFNB3). IFNb1 is used as a treatment for multiple sclerosis as it reduces the relapse rate. Besides, Interferon Alpha/Beta Receptor 1 (IFNa/bR1) has been identified as an interactor of IFNb, thus a binding ELISA assay was conducted to detect the interaction of recombinant human IFNb and recombinant human IFNa/bR1. Briefly, IFNb were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to EP300-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-IFNb pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IFNb and IFNa/bR1 was shown in Figure 1, and this effect was in a dose dependent manner.)

Interferon Beta (IFNb), Active Protein (Cat# AAA152231)

Full Name
Active Interferon Beta (IFNb)
Gene Names
Ifnb1; Ifb; IFNB; IFN-beta
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA152972_BIOACTIVITY13.jpg Bioactivity (Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.Thus, chemotaxis assay used 24-well microchemotaxis syste)

Interleukin 8 (IL8), Active Protein (Cat# AAA152972)

Full Name
Active Interleukin 8 (IL8)
Gene Names
IL8; CXCL8; AMCF-I
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153049_BIOACTIVITY13.jpg Bioactivity (S100A11 is a member of the S100 calcium-binding protein family ,it contains two EF-hand calcium-binding motifs and shares 82% amino acid sequence identity with mouse and rat S100A11 . S100 proteins are localized in the cytoplasm and nucleus of a wide rang)

S100 Calcium Binding Protein A11 (S100A11), Active Protein (Cat# AAA153049)

Full Name
Active S100 Calcium Binding Protein A11 (S100A11)
Gene Names
S100A11; MLN70; S100C; HEL-S-43
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153070_BIOACTIVITY13.jpg Bioactivity (GSTp (Glutathione S-transferase P) is an enzyme that plays an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 is identified as a CDK5 (Cyclin dependent kinase-5)

Glutathione S Transferase Pi (GSTp), Active Protein (Cat# AAA153070)

Full Name
Active Glutathione S Transferase Pi (GSTp)
Gene Names
GSTP1; PI; DFN7; GST3; GSTP; FAEES3
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153075_BIOACTIVITY13.jpg Bioactivity (Neurosecretory protein VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. Human VGF precursor is 615 amino acids (aa) in length. It contains an 22 aa signal sequence plus a 593 aa mature re)

VGF Nerve Growth Factor Inducible (VGF), Active Protein (Cat# AAA153075)

Full Name
Active VGF Nerve Growth Factor Inducible (VGF)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153080_BIOACTIVITY13.jpg Bioactivity (Pleiotrophin (PTN) is a 136 amino acid secreted heparin-binding cytokine that signals diverse functions, including lineage-specific differentiation of glial progenitor cells, neurite outgrowth, and angiogenesis. A considerable amount of research has been)

Pleiotrophin (PTN), Active Protein (Cat# AAA153080)

Full Name
Active Pleiotrophin (PTN)
Gene Names
PTN; HARP; HBNF; HBGF8; NEGF1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153088_BIOACTIVITY13.jpg Bioactivity (Poliovirus receptor-related 3 (PVRL3), also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Nectins and Nectin-like molecules (Necl) are families of cellular adhesion molecules invo)

Poliovirus Receptor Related Protein 3 (PVRL3), Active Protein (Cat# AAA153088)

Full Name
Active Poliovirus Receptor Related Protein 3 (PVRL3)
Gene Names
PVRL3; PPR3; PRR3; CD113; PVRR3; CDW113; NECTIN-3
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA258211_AD13.png Application Data (Immobilized mouse PVR-His at 10 ug/ml (100 ul/well) can bind mouse TIGIT-Fc, The EC50 of mouse TIGIT-Fc is 0.25-0.55 ug/ml.)

TIGIT, Active Protein (Cat# AAA258211)

Full Name
TIGIT Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Tigit; Vstm3
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA258213_AD13.jpg Application Data

TIGIT, Active Protein (Cat# AAA258213)

Full Name
TIGIT Protein, Mouse, Recombinant (mFc Tag)
Gene Names
Tigit; Vstm3
Purity
>95% as determined by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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