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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1600-1650 of 2875 product results
SDS-PAGE
Myostatin (MSTN), Active Protein (Cat# AAA149249)
Full Name
Active Myostatin (MSTN)
Gene Names
Mstn; Gdf8
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Bioactivity
(Apolipoprotein A2 (APOA2) is a major protein component of serum HDL. It is produced by the liver and is involved in cholesteryl ester formation and cholesterol transport from tissues to the liver. Polymorphisms of APOA2 are associated with disorders of ch)
Apolipoprotein A2 (APOA2), Active Protein (Cat# AAA153050)
Full Name
Active Apolipoprotein A2 (APOA2)
Gene Names
APOA2; apoAII; Apo-AII; ApoA-II
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
WB (Western Blot)
(Sample: Recombinant SIRT3, Mouse;Antibody: Rabbit Anti-Mouse SIRT3 Ab)
Sirtuin 3 (SIRT3), Active Protein (Cat# AAA148211)
Full Name
Active Sirtuin 3 (SIRT3)
Gene Names
Sirt3; Sir2l3; AI848213; 2310003L23Rik
Reactivity
Mus musculus (Mouse)
Applications
Activity Assay, Cell Culture
Purity
>92%
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human CD48 at 10 ug/ml (100 ul/well) can bind recombinant human 2B4 / CD244 with a linear range of 0.004-0.4 ug/ml.)
CD48, Active Protein (Cat# AAA257929)
Full Name
CD48 Protein, Human, Recombinant (His Tag)
Gene Names
CD48; BCM1; BLAST; hCD48; mCD48; BLAST1; SLAMF2; MEM-102
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit TNFalpha-mediated cytotoxicity in L929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.2-1ug/mL in the presence of 0.25 ng/mL recombinant human TNFalpha.)
TNFRSF1A, Active Protein (Cat# AAA257940)
Full Name
TNFRSF1A Protein, Human, Recombinant (His Tag)
Gene Names
TNFRSF1A; FPF; MS5; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; TNFR1-d2
Purity
>92% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit BMP4-induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 0.1-0.3 ug/ml in the presence of 50 ng/mL of recombinant human BMP4.)
BMPR1A/ALK-3, Active Protein (Cat# AAA258126)
Full Name
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc Tag)
Gene Names
Bmpr1a; ALK3; Bmpr; BMPR-IA; AU045487; 1110037I22Rik
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to induce activation of beta-catenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells. The ED50 for this effect is typically 0.1-0.5 ug/mL in the presence of 5 ng/mL recombinant mouse Wnt3a.)
RSPO1, Active Protein (Cat# AAA257963)
Full Name
RSPO1 Protein, Human, Recombinant (aa 1-146, His Tag)
Gene Names
RSPO1; RSPO; CRISTIN3
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
CCL22, Active Protein (Cat# AAA214259)
Full Name
Recombinant Human CCL22
Gene Names
CCL22; MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
(Human IL-2 (C145S) stimulates cell proliferation of the CTLL2 mouse cytotoxic T cells. The ED50 range ≥0.65 ng/ml)
Interleukin-2, Active Protein (Cat# AAA48459)
Full Name
Interleukin-2 (C145S), 22-153 aa, Human, E Coli (Bioactivity Validated)
Gene Names
IL2; IL-2; TCGF; lymphokine
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Application Data
Insulin Like Growth Factor 1 (IGF1), Active Protein (Cat# AAA146604)
Full Name
Active Insulin Like Growth Factor 1 (IGF1)
Gene Names
IGF1; MGF; IGFI; IGF-I
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Jun Proto-Oncogene, Active Protein (Cat# AAA38414)
Full Name
Recombinant Human Jun Proto-Oncogene
Gene Names
JUN; AP1; AP-1; c-Jun
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Hydroxyacid Oxidase-1/HAO-1, Active Protein (Cat# AAA48314)
Full Name
Recombinant Hydroxyacid Oxidase-1/HAO-1
Gene Names
Hao1; GOX; Gox1; Hao-1
Applications
Enzyme Activity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
Bioactivity
Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3, Active Protein (Cat# AAA177935)
Full Name
Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3 (C-Fc)
Gene Names
SIGLEC15; CD33L3; HsT1361; SIGLEC-15
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Application Data
HCC-1 (CCL14), Active Protein (Cat# AAA214225)
Full Name
Recombinant Human HCC-1 (CCL14)
Gene Names
CCL14; CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human CD48 at 10 ug/ml (100 ul/well) can bind recombinant human 2B4 / CD244 with a linear range of 0.004-0.4 ug/ml.)
2B4/CD244, Active Protein (Cat# AAA257819)
Full Name
2B4/CD244 Protein, Human, Recombinant (hFc Tag)
Gene Names
CD244; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4
Purity
>97% as determined by SDS-PAGE
Pricing
SDS-PAGE
(Figure annotation denotes ug of protein loaded and % gel used.)
Alphaenolase, Active Protein (Cat# AAA75217)
Full Name
Alphaenolase protein
Applications
SDS-PAGE
Purity
> 90% pure
Pricing
Bioactivity
(Rat EPO stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range )
Erythropoietin/EPO, Active Protein (Cat# AAA48388)
Full Name
Recombinant rat Erythropoietin/EPO protein
Applications
Bioactivity, SDS-PAGE
Purity
>95% by SDS-PAGE
Pricing
HPLC
(SARS COV-2 Spike S1 B.1.1.529 omicron HPLC. The purity of 2019-nCoV Spike B.1.1.529 omicron is greater than 95% as determined by SEC-HPLC.)
COVID 19 B.1.1.529 (Omicron) Spike S1 Coronavirus, Active Protein (Cat# AAA76127)
Full Name
COV2 Spike protein S1 Recombinant B.1.1.529 (Omicron)-His
Pricing
Bioactivity
(Motility Related Protein (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. It can enable ATPase-coupled inorganic anion transmembrane transporter activity. Involved in anion transmembrane transport ; renal tubular secretion)
Motility Related Protein (MRP1), Active Protein (Cat# AAA153071)
Full Name
Active Motility Related Protein (MRP1)
Gene Names
CD9; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
(Figure. Inhibition of FGF basic-dependent HUVEC proliferation after stimulated with PF4.)
Platelet Factor 4, Active Protein (Cat# AAA150080)
Full Name
Active Platelet Factor 4 (PF4)
Gene Names
Pf4; Cxcl4; Scyb4
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
WB (Western Blot)
(Figure. Western Blot)
Apolipoprotein C3, Active Protein (Cat# AAA150118)
Full Name
Active Apolipoprotein C3 (APOC3)
Gene Names
APOC3; APOCIII
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
Arginase (ARG), Active Protein (Cat# AAA148185)
Full Name
Active Arginase (ARG)
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Bioactivity
(Fibrinogen Gamma (FGg) is a component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. FGg can be polymerized with fibrinogen (FGA) and fibrinogen (FGB) to form an insoluble fibrin matrix, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human FGg and recombinant mouse FGA. Briefly, FGg was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FGA-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-FGg pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human FGg and recombinant mouse FGA was shown in Figure 1, the EC50 for this effect is 0.9 ug/mL.)
Fibrinogen Gamma (FGg), Active Protein (Cat# AAA161889)
Full Name
Active Fibrinogen Gamma (FGg)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
SDS-PAGE
C-C motif chemokine 19 protein (Ccl19), Active Protein (Cat# AAA114235)
Full Name
Recombinant Mouse C-C motif chemokine 19 protein (Ccl19) (Active)
Gene Names
Ccl19; ELC; CKb11; MIP3B; Scya19; exodus-3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Application Data
(Measured in a cell proliferation assay in mouse splenocytes. The ED50 for this effect is typically 0.6-3.2 ng/mL.)
BAFF/BLyS, Active Protein (Cat# AAA257823)
Full Name
BAFF/BLyS Protein, Human, Recombinant (hFc Tag)
Gene Names
TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Purity
>95% as determined by SDS-PAGE
Pricing
SDS-PAGE
PRDX4, Active Protein (Cat# AAA48624)
Full Name
PRDX4, 38-271aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
PRDX4; PRX-4; AOE372; AOE37-2; HEL-S-97n
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Bioactivity
(Fibroblast Growth Factor 9 (FGF9) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF9 was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. FGF9 secreted by HSC is a candidate activating ligand for hepatocyte FGFR4 functions, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human FGF9 and recombinant human FGFR4. Briefly, biotin-linked FGF9 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FGFR4-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30 min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of FGF9 and FGFR4 was shown in Figure 1, the EC50 for this effect is 0.23 ug/mL.)
Fibroblast Growth Factor 9 (FGF9), Active Protein (Cat# AAA161661)
Full Name
Active Fibroblast Growth Factor 9 (FGF9)
Gene Names
FGF9; GAF; FGF-9; SYNS3; HBFG-9; HBGF-9
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Collagen Type I Alpha 2 (COL1a2) is a major component of collagen type I found in skin, bone, muscle, tendons, ligaments and other connective tissues.The COL1a2 protein is essential for the assembly, secretion, and stability of collagen fibers, which are vital for tissue development and repair.Mutations in COL1A2 are associated with a variety of genetic disorders, such as osteogenesis imperfecta (dysplasia of the bones) and cutis laxa. These diseases are often accompanied by weak bones and loss of skin elasticity. Besides, Fibrillin 1 (FBN1) has been identified as an interactor of COL1a2, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse COL1a2 and recombinant human FBN1. Briefly, COL1a2 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FBN1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-COL1a2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant mouse COL1a2 and recombinant human FBN1 was shown in Figure 1, the EC50 for this effect is 2.53 ug/mL.)
Collagen Type I Alpha 2 (COL1a2), Active Protein (Cat# AAA161715)
Full Name
Active Collagen Type I Alpha 2 (COL1a2)
Gene Names
Col1a2; oim; Cola2; Cola-2; Col1a-2; AA960264; AI325291
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(S100 calcium-binding protein 9 (S100A9) also known as calgranulin B, is a member of the S100 family of secreted calcium binding proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Lactoferrin (LTF) is one of targets of S100A9, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse S100A9 and recombinant human LTF. Briefly, S100A9 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to LTF-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-S100A9 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant mouse S100A9 and recombinant human LTF was shown in Figure 1, the EC50 for this effect is 0.44 ug/mL.)
S100 Calcium Binding Protein A9 (S100A9), Active Protein (Cat# AAA161859)
Full Name
Active S100 Calcium Binding Protein A9 (S100A9)
Gene Names
S100a9; p14; Cagb; GAGB; L1Ag; BEE22; MRP14; 60B8Ag; AW546964
Applications
Activity Assay, Cell Culture
Purity
Greater than 80% by SDS-PAGE
Pricing
Bioactivity
(Figure. The binding activity of IL-10 with IL10Ra.Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Besides, Interleukin 10 Receptor Alpha (IL10Ra) has been identified as an interactor of IL-10, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse IL-10 and recombinant mouse IL10Ra. Briefly, IL-10 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to IL10Ra-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-IL-10 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IL-10 and IL10Ra was shown in Figure 1, and this effect was in a dose dependent manner.)
Interleukin 10, Active Protein (Cat# AAA150055)
Full Name
Active Interleukin 10 (IL10)
Gene Names
Il10; CSIF; Il-10
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Bioactivity
(17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3) belongs to the HSD17B family with NAD(P)H/NAD(P) -dependent oxidoreductase activity that catalyzes the interconversion between 17-ketosteroids and 17-hydroxysteroids to maintain the balance between les)
17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3), Active Protein (Cat# AAA153131)
Full Name
Active 17-Beta-Hydroxysteroid Dehydrogenase Type 3 (HSD17b3)
Gene Names
HSD17B3; EDH17B3; SDR12C2
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
SDS-PAGE
Interferon alpha-2, Active Protein (Cat# AAA114580)
Full Name
Recombinant Human Interferon alpha-2
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
SDS-PAGE
Interleukin 2 Receptor Alpha (IL2Ra), Active Protein (Cat# AAA148244)
Full Name
Active Interleukin 2 Receptor Alpha (IL2Ra)
Reactivity
Mouse
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Application Data
(Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 ug/mL.)
DLL1, Active Protein (Cat# AAA257987)
Full Name
DLL1 Protein, Human, Recombinant (His Tag)
Gene Names
DLL1; DL1; Delta; DELTA1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human CD47-His at 2 ug/ml (100 ul/well) can bind human SIRPa(V2)-mFc, the EC50 of human SIRPa(V2)-mFc is 2-14 ng/mL.)
SIRP alpha, Active Protein (Cat# AAA258063)
Full Name
SIRP alpha Protein, Human, Recombinant (ECD, SIRP alphaV2, mFc Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human PGF-mFc at 10 ug/mL (100 uL/well) can bind human VEGFR1-His. The EC50 of human VEGFR1-His is 0.19-0.43 ug/mL.)
PLGF/PGF, Active Protein (Cat# AAA257861)
Full Name
PLGF/PGF Protein, Human, Recombinant (mFc Tag)
Gene Names
PGF; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. 1. Immobilized mouse ErbB3-His at 10 ug/ml (100 ul/well) can bind biotinylated human NRG1 (isoform Beta1) with a linear range of 0.018-0.125 ug/ml. 2. Immobilized mouse ErbB3-His at 10 ug/ml (100 ul/well) can bind biotinylated human NRG1 (aa 2-246)-Fc with a linear range of 6.25-100 ng/ml.)
HER3/ERBB3, Active Protein (Cat# AAA258220)
Full Name
HER3/ERBB3 Protein, Mouse, Recombinant (His Tag)
Gene Names
Erbb3; Her3; C76256; Erbb-3; Erbb3r
Purity
>93% as determined by SDS-PAGE
Pricing
SDS-PAGE
TrkA, Active Protein (Cat# AAA258229)
Full Name
TrkA Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Ntrk1; Tkr; trk; TrkA; C80751
Purity
> 90% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein(ECD, His&AVI Tag)(Cat: AAA258587), the EC50 is 4-12 ng/mL.)
COVID 19 (BA.2.75) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258587)
Full Name
SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein (ECD, His & AVI Tag), Biotinylated
Purity
>90% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Bioactivity
(HTRF Assay for Recombinant PKN2 activity. 1 uM STK S1 substrate was incubated with different concentrations of PKN2 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Bioactivity
(HTRF Assay for Recombinant BRD2 (BD1+BD2) activity. 3 uM histone peptide H4K5/8/12/16(ac4) was incubated with BRD2 (BD1+BD2) in reaction buffer including 50 mM HEPES-NaOH pH 7.0, 0.1% BSA for 1 hour at room temperature. Anti-His antibody was used to detect reaction products.)
BRD2 (BD1+BD2), Active Protein (Cat# AAA60342)
Full Name
Recombinant BRD2 (BD1+BD2) protein
Purity
>=85%
Pricing
Bioactivity
NKG2-D Type II Integral Membrane (KLRK1), Active Protein (Cat# AAA243731)
Full Name
Recombinant Human NKG2-D Type II Integral Membrane Protein (KLRK1), Partial (Active)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Bioactivity
(IL-1RA is an agent that binds non-productively to the cell surface interleukin-1 receptor (IL-1R), the same receptor that binds interleukin 1 (IL-1), preventing IL-1 from sending a signal to that cell. Besides, Interleukin 1 Alpha (IL-1a) has been identified as an interactor of IL-1RA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human IL-1RA and recombinant human IL-1a. Briefly, IL1RA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to IL-1a-coated microtiter wells and incubated for 2 h at 37. Wells were washed with PBST and incubated for 1 h with anti-IL-1RA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IL-1RA and IL-1a was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of IL-1RA with IL-1a.)
Interleukin 1 Receptor Antagonist, Active Protein (Cat# AAA150086)
Full Name
Active Interleukin 1 Receptor Antagonist (IL1RA)
Gene Names
IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant human CES5A is 1300 pmol/min/ug.)
Carboxylesterase 5A (CES5A), Active Protein (Cat# AAA153140)
Full Name
Active Carboxylesterase 5A (CES5A)
Gene Names
CES5A; CES5; CES7; CAUXIN; CES4C1; HEL126
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Glutamine Synthetase, Active Protein (Cat# AAA39145)
Full Name
Recombinant Human Glutamine Synthetase, His Tag, Active
Gene Names
GLUL; GS; GLNS; PIG43; PIG59
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
SDS-PAGE
uGDH, Active Protein (Cat# AAA48625)
Full Name
uGDH, 1-494aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
UGDH; GDH; UGD; UDPGDH; UDP-GlcDH
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is typically 1-5 ng/ml.)
Thrombopoietin, Active Protein (Cat# AAA258262)
Full Name
Thrombopoietin Protein, Cynomolgus, Recombinant (His Tag)
Purity
>86% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is typically 1.6-6.4 ng/mL.)
Thrombopoietin, Active Protein (Cat# AAA258132)
Full Name
Thrombopoietin Protein, Mouse, Recombinant (His Tag)
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human PD1-His at 10 ug/mL (100 uL/well) can bind human PDCD1LG2-Fc. The EC50 of PDCD1LG2-Fc is 0.05-0.12 ug/mL.)
PD-L2, Active Protein (Cat# AAA257865)
Full Name
PD-L2 Protein, Human, Recombinant (hFc Tag)
Gene Names
PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human CD155a-His at 10ug/mL (100uL/well) can bind human TIGIT-Fc, the EC50 of human TIGIT-Fc is 0.03-0.2ug/mL.)
TIGIT, Active Protein (Cat# AAA257951)
Full Name
TIGIT Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
TIGIT; VSIG9; VSTM3; WUCAM
Purity
>95% as determined by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.