Filters
▼Clonality
▼Type
▼Reactivity
▼Gene Name
▼Isotype
▼Host
▼Application
▼Clone
▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1350-1400 of 2583 product results
Bioactivity
(Aryl Hydrocarbon Receptor (AhR), also known as bHLHE76, is a 110 kDa member of the bHLH/PAS transcription factor family. It is widely expressed (breast, lung, liver), and serves many functions. It is a ligand-activated transcription factor best known for its role in sensing xenobiotics and regulating the expression of genes involved in xenobiotic metabolism, including drug transporters and drug metabolizing enzymes. Heat Shock Protein 90kDa Alpha A1 (HSP90aA1) has been identified as an interactor of AhR, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human AhR and recombinant human HSP90aA1. Briefly, AhR were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to HSP90aA1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-AhR pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450 nm immediately. The binding activity of AhR and HSP90aA1 was shown in Figure 1, and this effect was in a dose dependent manner, the EC50 for this effect is 0.09 ug/mL.)
Aryl Hydrocarbon Receptor (AhR), Active Protein (Cat# AAA161844)
Full Name
Active Aryl Hydrocarbon Receptor (AhR)
Gene Names
AHR; bHLHe76
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(The classical role of ACHE is to terminate cholinergic neurotransmission by hydrolysis of acetylcholine (ACH). ACHE is thought to be involved in the pathology of Alzheimer's disease (AD) by accelerating the assembly of A beta peptides into fibrillar species through forming complexes with A beta via the peripheral anionic site on ACHE. ACHE inhibitors have been used to delay symptoms of AD patients by virtue of their ability to enhance ACH availability, as well as reduce amyloidogenesis and subsequent neurotoxicity. Its involvement in the cholinergic anti-inflammatory pathway connects ACHE with a possible marker of low-grade systemic inflammation in obesity, hypertension, coronary heart disease, and AD. The activity of recombinant mouse ACHE was measured by its ability to cleave Acetylthiocholine in the assay buffer 0.1 M sodium phosphate, 0.05% (w/v) Brij-35, pH 7.5. 50 uL of various concentrations of rmACHE (diluted by Assay Buffer) was added into the 96-well clear plate and the reaction was started by the addition of 50 ul substrate mixture of 200 uM acetylthiocholine and 100 uM DTNB. The final well serves as a negative control with no rmACHE, replaced with 50ul assay buffer and 50 ul substrate mixture. Read plate in kinetic mode for 5 minutes at an absorbance of 405 nm. The specific activity of recombinant mouse ACHE is >2200 nmol/min/ug.)
Acetylcholinesterase (ACHE), Active Protein (Cat# AAA161851)
Full Name
Active Acetylcholinesterase (ACHE)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 3. The sandard curve of Dns-Tyr-Val-NH2)
Peptidylglycine Alpha Amidating Monooxygenase (PAM), Active Protein (Cat# AAA161894)
Full Name
Active Peptidylglycine Alpha Amidating Monooxygenase (PAM)
Gene Names
PAM; PAL; PHM
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. TIMP-2 is a non N-glycosylated protein with a molecular mass of 22 kDa produced by a wide range of cell types, which inhibits MMPs non-covalently by the formation of binary complexes. TIMP-2 also has erythroidpotentiating and cell growth promoting activities. The activity of recombinant human TIMP2 was measured by its ability to inhibit rhMMP2 cleavage of a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. rhMMP2 was diluted to 100 ug/ml and activated with 1 mM APMA at 37 degree C for 1 hour and rhTIMP2 (MW: 51.75 KD) was diluted to different concentrations with the assay buffer. Mix 8 ul of rhTIMP2 curve dilutions, 12.8 ul of activated rhMMP-2, and 59.2 ul of assay buffer, including a control containing assay buffer and the diluted rhMMP-2 and incubate the reactions for 2 hours at 37 degree C. Loading 50 ul of the incubated mixtures which were diluted five-fold in assay buffer into empty wells of a plate, and start the reaction by adding 50 ul of 20 uM substrate. Include a substrate blank containing 50 ul of assay buffer and 50 ul of 20 uM substrate. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The result was shown in Figure 1 and it was obvious that recombinant human TIMP2 significantly decreased rhMMP2 activity. The inhibition IC50 was )
Tissue Inhibitors Of Metalloproteinase 2 (TIMP2), Active Protein (Cat# AAA161697)
Full Name
Active Tissue Inhibitors Of Metalloproteinase 2 (TIMP2)
Gene Names
TIMP2; DDC8; CSC-21K
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Urokinase Plasminogen Activator (uPA), also known as u-plasminogen activator or urokinase, is a highly-specific serine protease from the peptidase S1 family that cleaves plasminogen to form plasmin making it a key player in the plasminogen activator (PA) system. Expression of uPA is minimal in normal cells but is increased several fold in tumor cells by extracellular stimuli elevated in cancer and corresponds to poor outcomes in several types of cancer. Therefore, uPA has been identified as an excellent target for therapeutic development through inhibition of protease activity or though inhibition of uPA-dependent signaling while in complex with uPA receptor (uPAR). The activity assay of uPA was measured by its ability to cleave a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The reaction was performed in 50 mM Tris, 0.01% Tween-20, pH 8.5 (Assay Buffer), ainitiated by addition 50 uL of 0.4 ug/ml uPA (diluted by Assay Buffer) to 50 uL of 200 uM Substrate. Read at excitation and emission wavelengths of 380 nm and 460 nm (top read), respectively, in kinetic mode for 5 minutes. The specific activity of recombinant human uPA is >9600 pmol/min/ug.)
Plasminogen Activator, Urokinase (uPA), Active Protein (Cat# AAA161705)
Full Name
Active Plasminogen Activator, Urokinase (uPA)
Gene Names
PLAU; ATF; QPD; UPA; URK; u-PA; BDPLT5
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Collagen Type I Alpha 2 (COL1a2) is a major component of collagen type I found in skin, bone, muscle, tendons, ligaments and other connective tissues.The COL1a2 protein is essential for the assembly, secretion, and stability of collagen fibers, which are vital for tissue development and repair.Mutations in COL1A2 are associated with a variety of genetic disorders, such as osteogenesis imperfecta (dysplasia of the bones) and cutis laxa. These diseases are often accompanied by weak bones and loss of skin elasticity. Besides, Fibrillin 1 (FBN1) has been identified as an interactor of COL1a2, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse COL1a2 and recombinant human FBN1. Briefly, COL1a2 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to FBN1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-COL1a2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant mouse COL1a2 and recombinant human FBN1 was shown in Figure 1, the EC50 for this effect is 2.53 ug/mL.)
Collagen Type I Alpha 2 (COL1a2), Active Protein (Cat# AAA161715)
Full Name
Active Collagen Type I Alpha 2 (COL1a2)
Gene Names
Col1a2; oim; Cola2; Cola-2; Col1a-2; AA960264; AI325291
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Apolipoprotein C1 (APOC1), also known as Apo-CI; ApoC-I; apo-CIB; apoC-IB, is the smallest size apolipoprotein of all apolipoprotein C family (Mr = 6.6 kDa) and located at position 19q13.32. APOC1 is primarily expressed in the liver and activated when monocytes differentiate into macrophages. It plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. It has anti-inflammatory activity and also can promote the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells. Besides, Apolipoprotein A1 (APOA1) has been identified as an interactor of APOC1, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human APOC1 and recombinant human APOA1. Briefly, APOC1 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to APOA1-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-APOC1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human APOC1 and recombinant human APOA1 was shown in Figure 1, the EC50 for this effect is 0.46 ug/mL.)
Apolipoprotein C1 (APOC1), Active Protein (Cat# AAA161720)
Full Name
Active Apolipoprotein C1 (APOC1)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Transforming growth factor beta-3 (TGFb3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGFb3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. It also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Besides, Transforming Growth Factor Beta Receptor II (TGFbR2) has been identified as an interactor of TGFb3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human TGFb3 and recombinant human TGFbR2. Briefly, TGFb3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to TGFbR2-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-TGFb3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TGFb3 and TGFbR2 was shown in Figure 1, and this effect was in a dose dependent manner.)
Transforming Growth Factor Beta 3 (TGFb3), Active Protein (Cat# AAA152205)
Full Name
Active Transforming Growth Factor Beta 3 (TGFb3)
Gene Names
TGFB3; ARVD; TGF-beta3
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
SDS-PAGE
(SDS-PAGE)
Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA152226)
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
IL1B; IL-1B
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. Inhibition of A549 cells proliferation after stimulated with recombinant pig IFN-alpha.)
Interferon Alpha (IFNa), Active Protein (Cat# AAA152954)
Full Name
Active Interferon Alpha (IFNa)
Gene Names
IFNA1; IFN1@; IFN-ALPHA-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(The interleukin-1 receptor antagonist (IL-1RA) is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effec)
Interleukin 1 Receptor Antagonist (IL1RA), Active Protein (Cat# AAA153007)
Full Name
Active Interleukin 1 Receptor Antagonist (IL1RA)
Gene Names
Il1rn; IL-1ra
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL9 in V- bottom shaped 96-well microtiter plate.)
Galectin 9 (GAL9), Active Protein (Cat# AAA153024)
Full Name
Active Galectin 9 (GAL9)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Annexin A1 (ANXA1), also known as lipocortin I, belongs to the annexin family of Ca2 -dependent phospholipid-binding proteins that have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma)
Annexin A1 (ANXA1), Active Protein (Cat# AAA153126)
Full Name
Active Annexin A1 (ANXA1)
Gene Names
Anxa1; p35; Anx1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
AREG, Active Protein (Cat# AAA214278)
Full Name
Recombinant Human AREG
Gene Names
AREG; AR; SDGF; AREGB; CRDGF
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TNF, Active Protein (Cat# AAA214321)
Full Name
Recombinant Mouse TNF
Gene Names
Tnf; DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
Siglec-10, Active Protein (Cat# AAA177946)
Full Name
Recombinant Human Siglec-10 (C-mFc)
Gene Names
SIGLEC10; SLG2; PRO940; SIGLEC-10
Purity
>90% as determined by reducing SDS-PAGE
Pricing
Bioactivity
B7 Homolog 4/B7-H4/VTCN1 Biotinylated, Active Protein (Cat# AAA177958)
Full Name
Recombinant Human B7 Homolog 4/B7-H4/VTCN1 (C-Fc-Avi) Biotinylated
Gene Names
VTCN1; B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
FGL1, Active Protein (Cat# AAA177972)
Full Name
Recombinant Cynomolgus FGL1 (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Application Data
Interleukin 2 (IL2), Active Protein (Cat# AAA146606)
Full Name
Active Interleukin 2 (IL2)
Gene Names
Il2; Il-2
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Bioactivity
(Figure 1. The binding activity of GDNF with GFRa2.)
Glial Cell Line Derived Neurotrophic Factor, Active Protein (Cat# AAA150051)
Full Name
Active Glial Cell Line Derived Neurotrophic Factor (GDNF)
Gene Names
GDNF; ATF; ATF1; ATF2; HSCR3; HFB1-GDNF
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(Figure. The binding activity of IL-10 with IL10Ra.Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. IL-10 is a cytokine with multiple, pleiotropic, effects in immunoregulation and inflammation. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Besides, Interleukin 10 Receptor Alpha (IL10Ra) has been identified as an interactor of IL-10, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse IL-10 and recombinant mouse IL10Ra. Briefly, IL-10 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to IL10Ra-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-IL-10 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IL-10 and IL10Ra was shown in Figure 1, and this effect was in a dose dependent manner.)
Interleukin 10, Active Protein (Cat# AAA150055)
Full Name
Active Interleukin 10 (IL10)
Gene Names
Il10; CSIF; Il-10
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
Bioactivity
(Figure. The binding activity of IL4 with IL4R.)
Interleukin 4, Active Protein (Cat# AAA150061)
Full Name
Active Interleukin 4 (IL4)
Gene Names
Il4; Il4e12
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Bioactivity
(Figure. The binding activity of SDF1 with CCR1The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein. SDF1 is strongly chemotactic for lymphocytes. During embryogenesis, it directs the migration of hematopoietic cells from fetal liver to bone marrow and the formation of large blood vessels. CXCL12 is also chemotactic for mesenchymal stem cells and is expressed in the area of inflammatory bone destruction, where it mediates their suppressive effect on osteoclastogenesis. Besides, Chemokine C-C-Motif Receptor 1 (CCR1) has been identified as an interactor of SDF1, thus a binding ELISA assay was conducted to detect the interaction of recombinant rat SDF1 and recombinant rat CCR1. Briefly, SDF1 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to CCR1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-SDF1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of SDF1 and CCR1 was shown in Figure 1, and this effect was in a dose dependent manner.)
Stromal Cell Derived Factor 1, Active Protein (Cat# AAA150074)
Full Name
Active Stromal Cell Derived Factor 1 (SDF1)
Gene Names
Cxcl12; Sdf1
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Figure 1.Cell proliferation of ECV304 cells after stimulated with VEGFA.)
Vascular Endothelial Growth Factor A, Active Protein (Cat# AAA150078)
Full Name
Active Vascular Endothelial Growth Factor A (VEGFA)
Gene Names
VEGFA; VEGF
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
WB (Western Blot)
(Western BlotSample: Recombinant CTSA, Rat;Antibody: Rabbit Anti-Rat CTSA Ab)
Cathepsin A, Active Protein (Cat# AAA150088)
Full Name
Active Cathepsin A (CTSA)
Reactivity
Rattus norvegicus (Rat)
Applications
Activity Assay, Cell Culture
Purity
>92%
Pricing
Application Data
(Figure. The hemolysis activity of recombinant human CFB)
Complement Factor B, Active Protein (Cat# AAA150124)
Full Name
Active Complement Factor B (CFB)
Gene Names
CFB; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
Bioactivity
(Figure. The binding activity of CFHR3 with PRDX4)
Complement Factor H Related Protein 3, Active Protein (Cat# AAA150145)
Full Name
Active Complement Factor H Related Protein 3 (CFHR3)
Gene Names
CFHR3; FHR3; HLF4; CFHL3; FHR-3; DOWN16
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
SDS-PAGE
(SDS-PAGE of 73kDa Hsc70 protein)
Hsc70, Active Protein (Cat# AAA103775)
Full Name
Recombinant Human HSC70
Gene Names
HSPA8; LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; LAP-1; NIP71; HEL-33; HSPA10; HEL-S-72p
Applications
Functional Assay, Western Blot
Purity
Affinity Purified
Pricing
SDS-PAGE
(SDS-PAGE of 60kDa Hsp60 protein (AAA103776).)
Hsp60, Active Protein (Cat# AAA103776)
Full Name
Recombinant Human HSP60
Gene Names
HSPD1; HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60
Reactivity
Human
Applications
Functional Assay, Western Blot
Purity
Affinity Purified
Pricing
Application Data
PDGF-BB, Active Protein (Cat# AAA79160)
Full Name
Human PDGF-BB
Gene Names
PDGFB; SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
IL-1 beta, Active Protein (Cat# AAA79233)
Full Name
Human IL-1 beta
Gene Names
IL1B; IL-1; IL1F2; IL1-BETA
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
VEGF-E, Heparin-binding, Active Protein (Cat# AAA79256)
Full Name
Orf Virus VEGF-E, Heparin-binding
Reactivity
Orf virus
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Granzyme B, Active Protein (Cat# AAA79267)
Full Name
Mouse Granzyme B
Gene Names
GZMB; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
Reactivity
Mouse
Purity
> 97% by SDS-PAGE and HPLC analysis
Pricing
G-CSF, Active Protein (Cat# AAA79275)
Full Name
Mouse G-CSF
Gene Names
Csf3; Csfg; G-CSF; MGI-IG
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
Application Data
PDGF-BB, Active Protein (Cat# AAA79279)
Full Name
Human PDGF-BB
Gene Names
PDGFB; SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Application Data
FGF-4, Active Protein (Cat# AAA79290)
Full Name
Human FGF-4
Gene Names
FGF4; HST; KFGF; HST-1; HSTF1; K-FGF; HBGF-4
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
IL11, Active Protein (Cat# AAA75591)
Full Name
IL11 protein (Mouse)
Gene Names
IL11; AGIF; IL-11
Purity
> 98% by SDS-PAGE and HPLC analysis
Pricing
BMP6, Active Protein (Cat# AAA75597)
Full Name
BMP6 protein
Gene Names
BMP6; VGR; VGR1
Purity
> 95% pure
Pricing
Application Data
IL-4, Active Protein (Cat# AAA79122)
Full Name
Human IL-4
Gene Names
IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
GM-CSF, Active Protein (Cat# AAA79138)
Full Name
Human GM-CSF
Gene Names
CSF2; GMCSF
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
(Fig 2: Immobilized Recombinant 2019-nCoV Spike S1-His at 2ug/mL (100 uL/well) can bind Recombinant Human ACE2 with a linear range of 1.5-15 ng/mL.)
COVID 19 Spike S1 Coronavirus, Active Protein (Cat# AAA78533)
Full Name
Recombinant SARS-CoV-2 Spike S1 Protein with His tag and Avi
Applications
Functional Assay
Purity
>95% by SDS-PAGE.
Pricing
Application Data
Activin Receptor Type-2B (ACVR2B), Active Protein (Cat# AAA235620)
Full Name
Recombinant Human Activin Receptor Type-2B (ACVR2B), Partial
Gene Names
ACVR2B; HTX4; ACTRIIB; ActR-IIB
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Bioactivity
TSLP, Active Protein (Cat# AAA177943)
Full Name
Recombinant Human TSLP (C-10His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
Erythropoietin/EPO, Active Protein (Cat# AAA177969)
Full Name
Recombinant Mouse Erythropoietin/EPO (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
SDS-PAGE
Annexin A2 (ANXA2), Active Protein (Cat# AAA149253)
Full Name
Active Annexin A2 (ANXA2)
Gene Names
Anxa2; Cal1h; AW215814
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Interferon Gamma (IFNg), Active Protein (Cat# AAA146603)
Full Name
Active Interferon Gamma (IFNg)
Gene Names
Ifng; IFNG2
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Application Data
Interleukin 6 (IL6), Active Protein (Cat# AAA146609)
Full Name
Active Interleukin 6 (IL6)
Gene Names
IL6; IL-6; CHIL-6; interleukin-6
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
WB (Western Blot)
(Western BlotSample: Recombinant OPN, Human;Antibody: Rabbit Anti-Human OPN Ab)
Osteopontin (OPN), Active Protein (Cat# AAA146621)
Full Name
Active Osteopontin (OPN)
Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Reactivity
Homo sapiens (Human)
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>95%
Pricing
Sequence
Vimentin (VIM), Active Protein (Cat# AAA150975)
Full Name
Active Vimentin (VIM)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.