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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1800-1850 of 2875 product results
Bioactivity
(DHCR7 (7-dehydrocholesterol reductase) is a rate-limiting enzyme in cholesterol synthesis, which is mainly involved in the conversion of 7-dehydrocholesterol (7-DHC) to cholesterol. In the cholesterol biosynthetic pathway, this protease can reduce the C7-)
7-Dehydrocholesterol Reductase (DHCR7), Active Protein (Cat# AAA153112)
Full Name
Active 7-Dehydrocholesterol Reductase (DHCR7)
Gene Names
DHCR7; SLOS
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Figure 2. The hemagglutination assay of GAL4 in V- bottom shaped 96-well microtiter plate.)
Galectin 4 (GAL4), Active Protein (Cat# AAA153018)
Full Name
Active Galectin 4 (GAL4)
Gene Names
LGALS4; L36LBP
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Application Data
Interleukin 6 Receptor (IL6R), Active Protein (Cat# AAA148136)
Full Name
Active Interleukin 6 Receptor (IL6R)
Gene Names
Il6ra; Il6r; CD126; IL-6R; IL-6RA; IL-6R-alpha
Reactivity
Mouse
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Interleukin 11 (IL11), Active Protein (Cat# AAA148159)
Full Name
Active Interleukin 11 (IL11)
Gene Names
IL11; AGIF; IL-11
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Application Data
Maspin (SerpinB5), Active Protein (Cat# AAA214304)
Full Name
Recombinant Human Maspin (SerpinB5)
Gene Names
SERPINB5; PI5; maspin
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
(HTRF assay for RPS6KA4/RSK4 activity 1 uM STK S3 substrate was incubated with different concentrations of RPS6KA4/RSK4 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 10 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. The detection reagents were added and incubated with the reactions for 30 min. All operations and reactions were performed at room temperature, and HTRF assay was used to detect the enzymatic activity.)
RPS6KA4/RSK4, Active Protein (Cat# AAA60317)
Full Name
Recombinant RPS6KA4/RSK4 protein
Purity
>50%
Pricing
Bioactivity
(HTRF Assay for Recombinant NLK activity. 1 uM STK S3 substrate was incubated with different concentrations of NLK protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Bioactivity
(HTRF assay for BRD3 (BD1+BD2), Anti-His activity 3 uM histone peptide H4K5/8/12/16(ac4) was incubated with BRD3 (BD1+BD2) in reaction buffer including 50 mM HEPES-NaOH pH 7.4, 0.1% BSA for 1 hour at room temperature. Anti-His antibody was used to detect reaction products. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
BRD3 (BD1+BD2), Active Protein (Cat# AAA60343)
Full Name
Recombinant BRD3 (BD1+BD2) protein
Purity
>=85%
Pricing
Bioactivity
Ephrin-A5 (EFNA5), Active Protein (Cat# AAA243728)
Full Name
Recombinant Human Ephrin-A5 (EFNA5) (Active)
Gene Names
EFNA5; AF1; EFL5; RAGS; EPLG7; GLC1M; LERK7
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
WB (Western Blot)
(Sample: Recombinant IL10, Rat;Antibody: Rabbit Anti-Rat IL10 Ab)
Interleukin 10, Active Protein (Cat# AAA150056)
Full Name
Active Interleukin 10 (IL10)
Gene Names
Il10; IL10X
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant mouse CES1 is 158 pmol/min/ug.)
Carboxylesterase 1 (CES1), Active Protein (Cat# AAA153113)
Full Name
Active Carboxylesterase 1 (CES1)
Gene Names
Ces1g; Ces1; Ces-1; Ses-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Bioactivity
(Carbonic Anhydrase IX (CA9) also known as membrane antigen MN and renal cell carcinoma (RCC) associated antigen G250, is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. rhCA9 correspond)
Carbonic Anhydrase IX (CA9), Active Protein (Cat# AAA153124)
Full Name
Active Carbonic Anhydrase IX (CA9)
Gene Names
CA9; MN; CAIX
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
SDS-PAGE
Interleukin-8 (CXCL8), Active Protein (Cat# AAA114238)
Full Name
Recombinant Human Interleukin-8 (CXCL8), partial (Active)
Gene Names
CXCL8; IL8; NAF; GCP1; LECT; LUCT; NAP1; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Bioactivity
(Canine IL-1 alpha/IL-1F1 in a cell proliferation assay using D10.G4.1 mouse helper T cell. The ED50 range )
IL-1 alpha/IL-1F1, Active Protein (Cat# AAA48380)
Full Name
Recombinant canine IL-1 alpha/IL-1F1 protein
Applications
Bioactivity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
Bioactivity
Siglec-10 Biotinylated, Active Protein (Cat# AAA177959)
Full Name
Recombinant Human Siglec-10 (C-Fc-Avi) Biotinylated
Gene Names
SIGLEC10; SLG2; PRO940; SIGLEC-10
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
(Homing Associated Cell Adhesion Molecule (HCAM), also known as CD44, is a ubiquitously expressed transmembrane glycoprotein mediating cell responses to the extracellular microenvironment. CD44 is the major surface hyaluronan (HA) receptor, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human CD44 and biotinylated hyaluronan (HA). Briefly, biotin-linked HA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to CD44-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 1 hour, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human CD44 and biotinylated HA was shown in Figure 1, the EC50 for this effect is 0.08 ug/mL.)
Homing Associated Cell Adhesion Molecule (HCAM), Active Protein (Cat# AAA161763)
Full Name
Active Homing Associated Cell Adhesion Molecule (HCAM)
Gene Names
CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure 3. Cell proliferation of MCF-7 cells after stimulated with IGF1.)
Insulin Like Growth Factor 1 (IGF1), Active Protein (Cat# AAA161670)
Full Name
Active Insulin Like Growth Factor 1 (IGF1)
Gene Names
Igf1; Igf-1; Igf-I; C730016P09Rik
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
(Immobilized mouse PVR-His at 10 ug/ml (100 ul/well) can bind mouse TIGIT-Fc, The EC50 of mouse TIGIT-Fc is 0.25-0.55 ug/ml.)
TIGIT, Active Protein (Cat# AAA258211)
Full Name
TIGIT Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Tigit; Vstm3
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse SIRPA-His at 10 ug/ml (100 ul/well) can bind human CD47-Fc, The EC50 of human CD47-Fc is 0.05-0.13 ug/ml.)
SIRP alpha, Active Protein (Cat# AAA258215)
Full Name
SIRP alpha Protein, Mouse, Recombinant (ECD, His Tag)
Gene Names
Sirpa; Bit; P84; SIRP; SHP-1; CD172a; Ptpns1; SHPS-1; AI835480
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized Cynomolgus SLC39A6/LIV-1 His at 2 ug/mL (100 uL/well) can bind Rabbit Anti-SLC39A6/LIV-1 Antibody, the EC50 of Rabbit Anti-SLC39A6/LIV-1 Antibody is 15-100 ng/mL.)
SLC39A6/LIV-1, Active Protein (Cat# AAA258266)
Full Name
SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Immobilized Human Leptin at 2 ug/mL (100 uL/well) can bind Human Leptin Receptor (His & hFc Tag), the EC50 of Human Leptin Receptor (His & hFc Tag) is 70-420 ng/mL.)
Leptin, Active Protein (Cat# AAA257847)
Full Name
Leptin Protein, Human, Recombinant
Gene Names
LEP; OB; OBS; LEPD
Purity
>98% as determined by SDS-PAGE
Pricing
Bioactivity
(HTRF assay for MAP2K1 (MEK1) activity 1 uM TK substrate was incubated with different concentrations of MAP2K1 (MEK1) protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 5 nM SEB and 100 uM ATP for 1 hour. Then 10 ul detection reagents containing anti-TK antibody and SAXL665 (each of which was 1:100 diluted with 1× Detection Buffer) were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF KinEASE TK assay was used to detect the enzymatic activity.)
MAP2K1 (MEK1), Active Protein (Cat# AAA60313)
Full Name
Recombinant MAP2K1 (MEK1) protein
Purity
>80%
Pricing
Cytidine Deaminase, Active Protein (Cat# AAA38875)
Full Name
Recombinant Human Cytidine Deaminase
Gene Names
CDA; CDD
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
SDS-PAGE
(#ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
AKR1B10, Active Protein (Cat# AAA48534)
Full Name
AKR1B10, 1-316aa, Human, E Coli (Bioactivity Validated)
Gene Names
AKR1B10; HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
SDS-PAGE
(Figure 1. Human BAFF-R Protein, mFc Tag on SDS-PAGE under reducing condition.)
BAFF-R, Active Protein (Cat# AAA47223)
Full Name
Recombinant Human BAFF-R protein with C-terminal mouse Fc
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Applications
Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Pricing
Bioactivity
(Hydroxysteroid (17beta) dehydrogenase 1 (HSD17b1) is a steroidogenic enzyme that especially catalyzes the conversion of low potent 17keto-steroids to highly potent 17beta-hydroxysteroids. It has a dual function in estrogen activation and androgen inactiva)
17-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD17b1), Active Protein (Cat# AAA153130)
Full Name
Active 17-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD17b1)
Gene Names
HSD17B1; HSD17; EDHB17; EDH17B2; SDR28C1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.Thus, chemotaxis assay used 24-well microchemotaxis syste)
Interleukin 8 (IL8), Active Protein (Cat# AAA152971)
Full Name
Active Interleukin 8 (IL8)
Gene Names
IL8L2; IL8; CXCL8; EMF-1; CXCLi2
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Figure. The binding activity of FGF23 with FGFR2.Fibroblast growth factor 23 or FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate and vitamin D metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 decreases the reabsorption and increases excretion of phosphate and suppress 1-alpha-hydroxylase, reducing its ability to activate vitamin D and subsequently impairing calcium absorption. Besides, Fibroblast Growth Factor Receptor 2 (FGFR2) has been identified as an interactor of FGF23, thus a binding ELISA assay was conducted to detect the interaction of recombinant human FGF23 and recombinant human FGFR2. Briefly, FGF23 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to FGFR2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-FGF23 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of FGF23 and FGFR2 was shown in Figure 1, and this effect was in a dose dependent manner.)
Fibroblast Growth Factor 23, Active Protein (Cat# AAA150099)
Full Name
Active Fibroblast Growth Factor 23 (FGF23)
Gene Names
FGF23; ADHR; FGFN; HYPF; HFTC2; HPDR2; PHPTC
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
WB (Western Blot)
(Figure 4. Western BlotSample: Recombinant ANXA1, Mouse;Antibody: Rabbit Anti-Mouse ANXA1 Ab)
Annexin A1, Active Protein (Cat# AAA150137)
Full Name
Active Annexin A1 (ANXA1)
Gene Names
Anxa1; Lpc1; Anx-1; Lpc-1; Anx-A1; C430014K04Rik
Reactivity
Mus musculus (Mouse)
Applications
Activity Assay, Cell Culture
Purity
>92%
Pricing
Standard Curve (Sample)
C ReProtein (CRP), Active Protein (Cat# AAA149242)
Full Name
Active C Reactive Protein (CRP)
Gene Names
CRP; PTX1
Reactivity
Homo sapiens (Human)
Applications
Western Blot
Purity
Purity: >98% as determined by SDS-PAGE.
Purification Methods: Salt co-precipitation and ionic-Exchange chromatography.
Purification Methods: Salt co-precipitation and ionic-Exchange chromatography.
Pricing
Bioactivity
(Figure 2. Inhibition of A375 cells proliferation after stimulated with recombinant human MIA1)
Melanoma Inhibitory Activity Protein 1 (MIA1), Active Protein (Cat# AAA161927)
Full Name
Active Melanoma Inhibitory Activity Protein 1 (MIA1)
Gene Names
Mia; Mia1; Cdrap; CD-RAP
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
SDS-PAGE
Cytosolic Sulfotransferase Family 1A Member 3, Active Protein (Cat# AAA174592)
Full Name
Recombinant Human Cytosolic Sulfotransferase Family 1A Member 3 Protein
Gene Names
SULT1A3; STM; HAST; HAST3; M-PST; ST1A3; ST1A4; ST1A5; TL-PST; ST1A3/ST1A4
Purity
>95% as determined by SDS-PAGE.
Pricing
Bioactivity
(ADP-Glo assay for SMARCA (636-1131) activity (Data from ICEB Bioscience Inc.) 100 uM ATP and 10 nM DNA was incubated with different concentrations of SMARCA2 (636-1131) protein in a 10 ul reaction system containing 20 mM HEPES pH 7.5,10 mM MgCl2, 50 mM NaCl, 0.1%Tween-20, 1 mM DTT for 1 hour, 10 ul ADP-Glo Reagent was added to the products and incubated for 1 hour.Then 20 ul Kinase Detection Reagent incubated for 1 hour. All the operations and reactions were performed at RT. Luminescence measurement is collected by BMG.)
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human human B7-H2 at 1 ug/ml (100 ul/well) can bind human ICOS with a linear range of 1.6-200 ng/ml.)
ICOS ligand, Active Protein (Cat# AAA257977)
Full Name
ICOS ligand Protein, Human, Recombinant (ECD, His Tag)
Gene Names
ICOSLG; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human NCR3 at 10ug/mL (100uL/well) can bind human B7-H6 (16140-H02H), the EC50 of human B7-H6 is 20-100 ng/mL.)
B7-H6, Active Protein (Cat# AAA258050)
Full Name
B7-H6 Protein, Human, Recombinant (hFc Tag)
Gene Names
NCR3LG1; B7H6; B7-H6; DKFZp686O24166
Purity
>95% as determined by SDS-PAGE
Pricing
Aldose Reductase, Active Protein (Cat# AAA38715)
Full Name
Recombinant Human Aldose Reductase
Gene Names
AKR1B1; AR; ADR; ALR2; ALDR1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
Bioactivity
(Human IL-10 R alpha inhibits Human IL-10 induced cell proliferation in the MC/9 mouse mast cells. The ED50 range is )
IL-10 R alpha, Active Protein (Cat# AAA48321)
Full Name
Recombinant IL-10 R alpha
Gene Names
IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Applications
Bioactivity, SDS-PAGE
Purity
> 90% by SDS - PAGE.
Pricing
SDS-PAGE
Fumarase, Active Protein (Cat# AAA48502)
Full Name
Fumarase, 44-510aa, Human, E Coli (Bioactivity Validated)
Gene Names
FH; MCL; FMRD; LRCC; HLRCC; MCUL1
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
SDS-PAGE
Erythropoietin, Active Protein (Cat# AAA48918)
Full Name
Erythropoietin, 28-193aa, Human, His tag, Baculovirus (Bioactivity Validated)
Gene Names
EPO; EP; MVCD2
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
WB (Western Blot)
(Sample: Recombinant CIRBP, Human;Antibody: Rabbit Anti-Human CIRBP Ab)
Cold Inducible RNA Binding Protein (CIRBP), Active Protein (Cat# AAA148138)
Full Name
Active Cold Inducible RNA Binding Protein (CIRBP)
Gene Names
CIRBP; CIRP
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized Human Ephrin-A1 His at 2 ug/ml (100 ul/well) can bind Human EphA1 hFc, the EC50 of Human EphA1 hFc is 8.0-48.0 ng/mL.)
Ephrin-A1, Active Protein (Cat# AAA257945)
Full Name
Ephrin-A1 Protein, Human, Recombinant (His Tag)
Gene Names
EFNA1; B61; EFL1; ECKLG; EPLG1; LERK1; LERK-1; TNFAIP4
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized ACE2 Protein, Human, Recombinant (mFc Tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD-AVI & His Recombiant Protein, Biotinylated (40589-V27B-B), the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD-AVI & His Recombiant Protein, Biotinylated (40589-V27B-B) is 600-900 ng/mL.)
COVID 19 Spike S1+S2 ECD-AVI & His Coronavirus, Active Protein (Cat# AAA258084)
Full Name
SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD-AVI & His Recombinant Protein, Biotinylated
Purity
>85% as determined by SDS-PAGE
Pricing
Bioactivity
(carboxylesterase 1(CES1) also known as Liver carboxylesterase 1 is a serine esterase and member of a large multigene carboxylesterase family. The protein Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydr)
Carboxylesterase 1 (CES1), Active Protein (Cat# AAA153114)
Full Name
Active Carboxylesterase 1 (CES1)
Gene Names
Ces1g; Ces1; Ces-1; Ses-1
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Bioactivity
(Pyruvate carboxylase (PC) is a mitochondrial, biotin-containing enzyme catalyzing the ATP-dependent synthesis of oxaloacetate from pyruvate and bicarbonate, with a critical anaplerotic role in sustaining the brain metabolism. Pyruvate carboxylase (PC) def)
Pyruvate Carboxylase (PC), Active Protein (Cat# AAA153136)
Full Name
Active Pyruvate Carboxylase (PC)
Gene Names
PC; PCB
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
SDS_PAGE
(Figure 3. SDS-PAGESample: Active recombinant SPC, Mouse)
Surfactant Associated Protein C (SPC), Active Protein (Cat# AAA149247)
Full Name
Active Surfactant Associated Protein C (SPC)
Gene Names
Sftpc; SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
Reactivity
Mus musculus (Mouse)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
SDS-PAGE
Amphiregulin protein (AREG), Active Protein (Cat# AAA114243)
Full Name
Recombinant Human Amphiregulin protein (AREG) (Active)
Gene Names
AREG; AR; SDGF; AREGB; CRDGF
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
SDS-PAGE
Receptor tyrosine-protein kinase erbB-2 (ERBB2), Active Protein (Cat# AAA113681)
Full Name
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial (Active)
Gene Names
ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Carboxyl Ester Lipase/CEL, Active Protein (Cat# AAA48319)
Full Name
Recombinant Carboxyl Ester Lipase/CEL
Gene Names
Cel; BAL; 1810036E18Rik
Applications
Enzyme Activity, SDS-PAGE
Purity
> 90% by SDS - PAGE
Pricing
Bioactivity
Thymic Stromal Lymphopoietin/TSLP, Active Protein (Cat# AAA177974)
Full Name
Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
Bioactivity
(Fatty acid binding protein-4 (FABP4) is a member of a large superfamily of lipid binding proteins that are expressed in a tissue specific manner. FABP4 is one of ten cytoplasmic FABPs that are 14-15 kDa in size and range from 126-140 amino acids (aa) in length. Although all are highly conserved in their tertiary structure, there is only modest aa identity between any two members. Lipase, Hormone Sensitive (LIPE) has been identified as an interactor of FABP4, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant mouse FABP4 and recombinant human LIPE. Briefly, FABP4 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to LIPE-coated microtiter wells and incubated for 1h at 37 degree C. Wells were aspirated and incubated for 1h with anti-FABP4 mAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450 nm immediately. The binding activity of FABP4 and LIPE was shown in Figure 1, and this effect was in a dose dependent manner. The EC50 for this effect is 0.23 ug/mL.)
Fatty Acid Binding Protein 4 (FABP4), Active Protein (Cat# AAA161857)
Full Name
Active Fatty Acid Binding Protein 4 (FABP4)
Gene Names
Fabp4; Ap2; Lbpl; 422/aP2; ALBP/Ap2
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.