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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 1800-1850 of 2567 product results


product-image-AAA153110_BIOACTIVITY13.jpg Bioactivity (Interleukin-29 (IL-29) is a member of the helical cytokine family and is a type III interferon. It is also known as IFNlambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 plays an important role in host)

Interleukin 29 (IL29), Active Protein (Cat# AAA153110)

No reviews yet
Full Name
Active Interleukin 29 (IL29)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153112_BIOACTIVITY13.png Bioactivity (DHCR7 (7-dehydrocholesterol reductase) is a rate-limiting enzyme in cholesterol synthesis, which is mainly involved in the conversion of 7-dehydrocholesterol (7-DHC) to cholesterol. In the cholesterol biosynthetic pathway, this protease can reduce the C7-)

7-Dehydrocholesterol Reductase (DHCR7), Active Protein (Cat# AAA153112)

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Full Name
Active 7-Dehydrocholesterol Reductase (DHCR7)
Gene Names
DHCR7; SLOS
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153125_BIOACTIVITY13.jpg Bioactivity (Carbonic Anhydrase IX (CA9) also known as membrane antigen MN and renal cell carcinoma (RCC) associated antigen G250, is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. rhCA9 correspond)

Carbonic Anhydrase IX (CA9), Active Protein (Cat# AAA153125)

No reviews yet
Full Name
Active Carbonic Anhydrase IX (CA9)
Gene Names
CA9; MN; CAIX
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153128_BIOACTIVITY13.jpg Bioactivity (Interleukin 37, also known as Interleukin 1 Zeta (IL1z), is an anti-inflammatory cytokine. Interleukines are cytokines that make an important part of immune signaling. It belongs to the interleukin-1 family. IL-37 plays a role in protecting the body again)

Interleukin 1 Zeta (IL1z), Active Protein (Cat# AAA153128)

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Full Name
Active Interleukin 1 Zeta (IL1z)
Gene Names
IL37; FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153138_BIOACTIVITY13.jpg Bioactivity (IL36G (Interleukin 36 gamma), also known as IL-1F9 and IL-1H1 is a member of the IL-1 family of cytokines. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferati)

Interleukin 1 Family, Member 9 (IL1F9), Active Protein (Cat# AAA153138)

No reviews yet
Full Name
Active Interleukin 1 Family, Member 9 (IL1F9)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA214257_AD13.png Application Data

IL22, Active Protein (Cat# AAA214257)

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Full Name
Recombinant Human IL22
Gene Names
IL22; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214263_AD13.png Application Data

GMFB, Active Protein (Cat# AAA214263)

No reviews yet
Full Name
Recombinant Human GMFB
Gene Names
GMFB; GMF
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA173576_SDS_PAGE15.jpg SDS-PAGE

Carbonic Anhydrase IX / CA9, Active Protein (Cat# AAA173576)

No reviews yet
Full Name
Recombinant Human Carbonic Anhydrase IX / CA9 Protein (His tag)
Gene Names
CA9; MN; CAIX
Purity
> 95 % as determined by SDS-PAGE
Pricing
product-image-AAA173585_SDS_PAGE15.jpg SDS-PAGE

IL1R1 / CD121a, Active Protein (Cat# AAA173585)

No reviews yet
Full Name
Recombinant Mouse IL1R1 / CD121a Protein (His tag)
Gene Names
Il1r1; IL-iR; CD121a; CD121b; IL-1R1; Il1r-1
Purity
> 95 % as determined by SDS-PAGE
Pricing
product-image-AAA177964_BIOACTIVITY13.jpg Bioactivity

Tumor-associated Calcium Signal Transducer 2/TROP-2, Active Protein (Cat# AAA177964)

No reviews yet
Full Name
Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (248AA, C-Fc)
Gene Names
TACSTD2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA146599_AD11.jpg Application Data

Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF), Active Protein (Cat# AAA146599)

No reviews yet
Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
product-image-AAA146602_AD8.jpg Application Data

Interferon Gamma (IFNg), Active Protein (Cat# AAA146602)

No reviews yet
Full Name
Active Interferon Gamma (IFNg)
Gene Names
Ifng; Ifg; IFN-g
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146611_AD10.jpg Application Data

Macrophage Inflammatory Protein 1 Alpha (MIP1a), Active Protein (Cat# AAA146611)

No reviews yet
Full Name
Active Macrophage Inflammatory Protein 1 Alpha (MIP1a)
Gene Names
CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146612_SDS_PAGE7.jpg SDS-PAGE

Matrix Metalloproteinase 2 (MMP2), Active Protein (Cat# AAA146612)

No reviews yet
Full Name
Active Matrix Metalloproteinase 2 (MMP2)
Gene Names
MMP2; CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
product-image-AAA146619_AD8.jpg Application Data

Insulin (INS), Active Protein (Cat# AAA146619)

No reviews yet
Full Name
Active Insulin (INS)
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148123_AD11.jpg Application Data

Interleukin 17 Receptor C (IL17RC), Active Protein (Cat# AAA148123)

No reviews yet
Full Name
Active Interleukin 17 Receptor C (IL17RC)
Gene Names
IL17RC; CANDF9; IL17RL; IL17-RL
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148128_AD8.jpg Application Data

V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC), Active Protein (Cat# AAA148128)

No reviews yet
Full Name
Active V-Myc Myelocytomatosis Viral Oncogene Homolog (MYC)
Gene Names
MYC; MRTL; MYCC; c-Myc; bHLHe39
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148148_AD11.jpg Application Data

Neuraminidase (NEU), Active Protein (Cat# AAA148148)

No reviews yet
Full Name
Active Neuraminidase (NEU)
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
product-image-AAA148250_BIOACTIVITY13.jpg Bioactivity (Figure 2. Cell proliferation of 3T3 cells after stimulated with AGE.)

Advanced Glycation End Product (AGE), Active Protein (Cat# AAA148250)

No reviews yet
Full Name
Active Advanced Glycation End Product (AGE)
Applications
Activity Assay, Cell Culture
Purity
Purity: >90% as determined by SDS-PAGE.
Purification Methods: Salt co-precipitation and ionic-Exchange chromatography.
Pricing
product-image-AAA150049_AD8.png Bioactivity (Figure 2. Inhibition of A549 cells proliferation after stimulated with IFN-.)

Interferon Alpha, Active Protein (Cat# AAA150049)

No reviews yet
Full Name
Active Interferon Alpha (IFNa)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA150067_AD11.png Application Data (Figure. The chemotactic effect of recombinant human MIP1-on Jurkat cells.)

Macrophage Inflammatory Protein 1 Beta, Active Protein (Cat# AAA150067)

No reviews yet
Full Name
Active Macrophage Inflammatory Protein 1 Beta (MIP1b)
Gene Names
CCL4; ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150076_BIOACTIVITY10.jpg Bioactivity (Figure. The binding activity of TIMP3 with MMP2.Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) is an protein belongs to the tissue inhibitor of metalloproteinases family. They are inhibitors of the matrix metalloproteinases. TIMP-3 is the only member of the TIMP family which is found exclusively in the extracellular matrix (ECM). It is regulated in a cell cycle-dependent fashion in certain cell types and may serve as a marker for terminal differentiation. Besides, Matrix Metalloproteinase 2 (MMP2) has been identified as an interactor of TIMP3, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse TIMP3 and recombinant mouse MMP2. Briefly, TIMP3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100ul were then transferred to MMP2-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-TIMP3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TIMP3 and MMP2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Tissue Inhibitors Of Metalloproteinase 3, Active Protein (Cat# AAA150076)

No reviews yet
Full Name
Active Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
Gene Names
Timp3; Timp-3
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150094_BIOACTIVITY10.jpg Bioactivity (Figure. The binding activity of IL1b with IL1R1.)

Interleukin 1 Beta, Active Protein (Cat# AAA150094)

No reviews yet
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
Il1b; IL-1F2
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150095_WB13.png WB (Western Blot) (Western Blot Sample: Recombinant PIIINP, Human;Antibody: Rabbit Anti-Human PIIINP Ab)

Procollagen III N-Terminal Propeptide, Active Protein (Cat# AAA150095)

No reviews yet
Full Name
Active Procollagen III N-Terminal Propeptide (PIIINP)
Gene Names
COL3A1; EDS4A; EDSVASC; PMGEDSV
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
product-image-AAA150112_BIOACTIVITY13.jpg Bioactivity (Myostatin (MSTN) also known as growth differentiation factor 8 (GDF-8) is a member of the TGF beta protein family. Myostatin is a secreted growth differentiation factor that produced and released by myocytes. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Besides, Bone Morphogenetic Protein 1 (BMP1) has been identified as an interactor of MSTN, thus a binding ELISA assay was conducted to detect the interaction of recombinant human MSTN and recombinant human BMP1. Briefly, MSTN were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to BMP1-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-MSTN pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of MSTN and BMP1 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of MSTN with BMP1.)

Myostatin, Active Protein (Cat# AAA150112)

No reviews yet
Full Name
Active Myostatin (MSTN)
Gene Names
MSTN; GDF8; MSLHP
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150147_AD11.jpg Application Data (Semaphorin-3F (SEMA3F) is a member of semaphorins family. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues. Semaphorins not only guide axons in development, but also have major roles in immune function (classes 4, 6, and 7) and the development of bones. Class 3 semaphorins are one of the most versatile semaphorin classes, in which Sema3a is the most studied. Besides, SEMA3F is deleted or downregulated in many metastatic tumors. To test the effect of SEMA3F on inhibit cell proliferation, human lung carcinoma cells A549 were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of recombinant human SEMA3F. After incubated for 48h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37. Proliferation of A549 cells after incubation with SEMA3F for 48h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 assay after incubation with recombinant SEMA3F for 48h. The result was shown in Figure 2. It was obvious that SEMA3F significantly increased cell viability of A549 cells. (A) A549 cells cultured in DMEM, stimulated with 100ng/mL SEMA3F for 48h; (B) Unstimulated A549 cells cultured in DMEM for 48h.Figure. Cell proliferation of A549 cells inhibtion by stimulating with SEMA3F.)

Semaphorin 3F, Active Protein (Cat# AAA150147)

No reviews yet
Full Name
Active Semaphorin 3F (SEMA3F)
Gene Names
SEMA3F; SEMA4; SEMAK; SEMA-IV
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150560_SDS_PAGE11.jpg SDS-PAGE (Figure. SDS-PAGE)

Fibroblast Growth Factor 10 (FGF10), Active Protein (Cat# AAA150560)

No reviews yet
Full Name
Active Fibroblast Growth Factor 10 (FGF10)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA150971_SEQUENCE10.jpg Sequence

Colony Stimulating Factor 1, Macrophage (MCSF), Active Protein (Cat# AAA150971)

No reviews yet
Full Name
Active Colony Stimulating Factor 1, Macrophage (MCSF)
Gene Names
Csf1; op; Csfm; MCSF; C87615
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA150974_SEQUENCE10.jpg Sequence

Sex Hormone Binding Globulin (SHBG), Active Protein (Cat# AAA150974)

No reviews yet
Full Name
Active Sex Hormone Binding Globulin (SHBG)
Gene Names
SHBG; ABP; SBP; TEBG
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA152021_SDS_PAGE10.jpg SDS_PAGE

Perforin 1 (PRF1), Active Protein (Cat# AAA152021)

No reviews yet
Full Name
Active Perforin 1 (PRF1)
Gene Names
PRF1; P1; PFP; FLH2; PFN1; HPLH2
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>80%
Pricing
product-image-AAA114580_SDS_PAGE15.jpg SDS-PAGE

Interferon alpha-2, Active Protein (Cat# AAA114580)

No reviews yet
Full Name
Recombinant Human Interferon alpha-2
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA177935_BIOACTIVITY13.jpg Bioactivity

Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3, Active Protein (Cat# AAA177935)

No reviews yet
Full Name
Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3 (C-Fc)
Gene Names
SIGLEC15; CD33L3; HsT1361; SIGLEC-15
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177938_BIOACTIVITY13.jpg Bioactivity

IL-36 Receptor Antagonist Protein/IL-36RN/IL-1F5, Active Protein (Cat# AAA177938)

No reviews yet
Full Name
Recombinant Human IL-36 Receptor Antagonist Protein/IL-36RN/IL-1F5
Gene Names
IL36RN; FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA177959_BIOACTIVITY13.jpg Bioactivity

Siglec-10 Biotinylated, Active Protein (Cat# AAA177959)

No reviews yet
Full Name
Recombinant Human Siglec-10 (C-Fc-Avi) Biotinylated
Gene Names
SIGLEC10; SLG2; PRO940; SIGLEC-10
Purity
>95% as determined by reducing SDS-PAGE
Pricing
product-image-AAA214282_AD13.png Application Data

TFF2, Active Protein (Cat# AAA214282)

No reviews yet
Full Name
Recombinant Human TFF2
Gene Names
TFF2; SP; SML1
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA149237_WB8.jpg WB (Western Blot) (Sample: Recombinant MMP9, Porcine; Antibody: Rabbit Anti-Porcine MMP9 Ab)

Matrix Metalloproteinase 9 (MMP9), Active Protein (Cat# AAA149237)

No reviews yet
Full Name
Active Matrix Metalloproteinase 9 (MMP9)
Gene Names
MMP9; GELB; CLG4B; MMP-9; MANDP2
Reactivity
Sus scrofa; Porcine (Pig)
Applications
Activity Assay, Cell Culture
Purity
>94%
Pricing
product-image-AAA146598_AD10.jpg Application Data

Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF), Active Protein (Cat# AAA146598)

No reviews yet
Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GMCSF)
Gene Names
CSF2; GMCSF
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146601_AD10.jpg Application Data

Interferon Gamma (IFNg), Active Protein (Cat# AAA146601)

No reviews yet
Full Name
Active Interferon Gamma (IFNg)
Gene Names
IFNG; IFG; IFI
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146604_AD8.jpg Application Data

Insulin Like Growth Factor 1 (IGF1), Active Protein (Cat# AAA146604)

No reviews yet
Full Name
Active Insulin Like Growth Factor 1 (IGF1)
Gene Names
IGF1; MGF; IGFI; IGF-I
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146610_AD8.jpg Application Data

Interleukin 6 (IL6), Active Protein (Cat# AAA146610)

No reviews yet
Full Name
Active Interleukin 6 (IL6)
Gene Names
Il6; Il-6
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146615_AD8.jpg Application Data

Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA146615)

No reviews yet
Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
Tnf; DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146616_AD10.jpg Application Data

Tumor Necrosis Factor Beta (TNFb), Active Protein (Cat# AAA146616)

No reviews yet
Full Name
Active Tumor Necrosis Factor Beta (TNFb)
Gene Names
LTA; LT; TNFB; TNFSF1; TNLG1E
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA146622_AD8.jpg Application Data

Osteopontin (OPN), Active Protein (Cat# AAA146622)

No reviews yet
Full Name
Active Osteopontin (OPN)
Gene Names
SPP1; OPN; BNSP; BSPI; ETA-1
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA146623_WB8.jpg WB (Western Blot) (Western BlotSample: Recombinant HRG, Human;Antibody: Rabbit Anti-Human HRG Ab)

Histidine Rich Glycoprotein (HRG), Active Protein (Cat# AAA146623)

No reviews yet
Full Name
Active Histidine Rich Glycoprotein (HRG)
Gene Names
HRG; HPRG; HRGP; THPH11
Reactivity
Homo sapiens (Human)
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>98%
Pricing
product-image-AAA146624_WB8.jpg WB (Western Blot) (Figure 4. Western BlotSample: Recombinant LMTK3, Human;Antibody: Rabbit Anti-Human LMTK3 Ab)

Lemur Tyrosine Kinase 3 (LMTK3), Active Protein (Cat# AAA146624)

No reviews yet
Full Name
Active Lemur Tyrosine Kinase 3 (LMTK3)
Gene Names
LMTK3; LMR3; TYKLM3; PPP1R101
Reactivity
Homo sapiens (Human)
Applications
Invitro Assay, Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA148129_AD8.jpg Application Data

Interleukin 15 (IL15), Active Protein (Cat# AAA148129)

No reviews yet
Full Name
Active Interleukin 15 (IL15)
Gene Names
IL15; IL-15
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148141_AD10.jpg Application Data

Interleukin 16 (IL16), Active Protein (Cat# AAA148141)

No reviews yet
Full Name
Active Interleukin 16 (IL16)
Gene Names
IL16; LCF; NIL16; PRIL16; prIL-16
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA148143_AD8.jpg Application Data

Vascular Endothelial Growth Factor 121 (VEGF121), Active Protein (Cat# AAA148143)

No reviews yet
Full Name
Active Vascular Endothelial Growth Factor 121 (VEGF121)
Gene Names
VEGFA; VPF; VEGF; MVCD1
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
product-image-AAA152174_BIOACTIVITY13.png Bioactivity (Galectin-12 is a member of a family of mammalian lectins known as galectins. The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. Galectin-12 is predominantly expressed in adipose tissue and detected also in macrophages and other leukocytes. It plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis, metastasis, apoptosis. In this case, we chose rabbit erythrocyte (RaE) to assay its ability of agglutination. A general procedure for hemagglutination assay (or haemagglutination assay; HA) is as follows, two-fold dilute the recombinant Hu GAL12 with 0.9% sodium chloride injection, add 50uL a serial dilution of GAL12 to each well of a U or V-bottom shaped 96-well microtiter plate. The final well serves as a negative control with no GAL12, replace with 50uL 0.9% sodium chloride injection. Then add 50uL 1% rabbit erythrocyte to each well and mixed gently. The plate is incubated for 3 hours at room temperature. The results are shown in Figure 1. It was obvious that the minimal effective concentration of GAL12 is 0.781 ug/mL.)

Galectin 12 (GAL12), Active Protein (Cat# AAA152174)

No reviews yet
Full Name
Active Galectin 12 (GAL12)
Gene Names
LGALS12; GAL12; GRIP1
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA152177_BIOACTIVITY13.png Bioactivity (Galectin 8 (GAL8), also known as prostate carcinoma tumor antigen 1 (PCTA1) in human, is a tandem repeat-type galectin. is a member of the lectin family, of which 14 mammalian galectins have been identified. It is also a member of the beta-galactoside-binding protein family that plays an important role in cell-cell adhesion, cell-matrix interactions, macrophage activation, angiogenesis, metastasis, apoptosis. In this case, we chose rabbit erythrocyte (RaE) to assay its ability of agglutination. A general procedure for hemagglutination assay (or haemagglutination assay; HA) is as follows, two-fold dilute the recombinant Bovine GAL8 with 0.9% sodium chloride injection, add 50uL a serial dilution of GAL8 to each well of a U or V-bottom shaped 96-well microtiter plate. The final well serves as a negative control with no GAL8, replace with 50uL 0.9% sodium chloride injection. Then add 50uL 1% rabbit erythrocyte to each well and mixed gently. The plate is incubated for 3 hours at room temperature. The results are shown in Figure 1. It was obvious that the minimal effective concentration of GAL8 is 0.781 ug/mL.)

Galectin 8 (GAL8), Active Protein (Cat# AAA152177)

No reviews yet
Full Name
Active Galectin 8 (GAL8)
Gene Names
LGALS8; galectin-8
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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