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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 1850-1900 of 2583 product results


product-image-AAA153135_BIOACTIVITY11.jpg Bioactivity (One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant Rat CES3 is 1200 pmol/min/ug.)

Carboxylesterase 3 (CES3), Active Protein (Cat# AAA153135)

Full Name
Active Carboxylesterase 3 (CES3)
Gene Names
Ces1d; Ces3
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153136_BIOACTIVITY13.jpg Bioactivity (Pyruvate carboxylase (PC) is a mitochondrial, biotin-containing enzyme catalyzing the ATP-dependent synthesis of oxaloacetate from pyruvate and bicarbonate, with a critical anaplerotic role in sustaining the brain metabolism. Pyruvate carboxylase (PC) def)

Pyruvate Carboxylase (PC), Active Protein (Cat# AAA153136)

Full Name
Active Pyruvate Carboxylase (PC)
Gene Names
PC; PCB
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153140_BIOACTIVITY11.jpg Bioactivity (One unit of enzyme activity is defined as the 1ug of enzyme required to convert 1pmol of 4-Nitrophenyl acetate to 4-Nitrophenol in 1min at 37 degree C. The specific activity of recombinant human CES5A is 1300 pmol/min/ug.)

Carboxylesterase 5A (CES5A), Active Protein (Cat# AAA153140)

Full Name
Active Carboxylesterase 5A (CES5A)
Gene Names
CES5A; CES5; CES7; CAUXIN; CES4C1; HEL126
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153141_BIOACTIVITY13.jpg Bioactivity (PNGase F (Peptide-N-glycosidase F) is a kind of enzymes for the deglycosylation of glycoproteins. The enzyme releases asparagine-linked oligosaccharides from glycoproteins and glycopeptides by hydrolyzing the amide of the asparagine (Asn) side chain. Thus)

Peptide-N4-N-Acetyl-Beta-D-Glucosaminyl Asparagine Amidase F (PNGaseF), Active Protein (Cat# AAA153141)

Full Name
Active Peptide-N4-N-Acetyl-Beta-D-Glucosaminyl Asparagine Amidase F (PNGaseF)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153036_BIOACTIVITY13.jpg Bioactivity (Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. Th)

Tissue Plasminogen Activator (tPA), Active Protein (Cat# AAA153036)

Full Name
Active Tissue Plasminogen Activator (tPA)
Gene Names
PLAT; TPA; T-PA
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153042_BIOACTIVITY13.jpg Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153042)

Full Name
Active Interleukin 1 Beta (IL1b)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153043_BIOACTIVITY13.jpg Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153043)

Full Name
Active Interleukin 1 Beta (IL1b)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153044_BIOACTIVITY13.jpg Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153044)

Full Name
Active Interleukin 1 Beta (IL1b)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153047_BIOACTIVITY13.jpg Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153047)

Full Name
Active Interleukin 1 Beta (IL1b)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153048_BIOACTIVITY13.jpg Bioactivity (Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)

Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153048)

Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
IL1B; IL1-BETA
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153052_BIOACTIVITY13.jpg Bioactivity (TLR2 is a member of TLR family which is type I transmembrane proteins with a large number of extracellular leucine-rich repeats (LRRs) and a cytoplasmic Toll/IL-1 receptor (TIR) domain. Human TLR2 is synthesized as a 784 amino acid precursor that contains)

Toll Like Receptor 2 (TLR2), Active Protein (Cat# AAA153052)

Full Name
Active Toll Like Receptor 2 (TLR2)
Gene Names
TLR2; TIL4; CD282
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153055_BIOACTIVITY13.jpg Bioactivity (Fibroblast growth factor 23 or FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate and vitamin D metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 decrea)

Fibroblast Growth Factor 23 (FGF23), Active Protein (Cat# AAA153055)

Full Name
Active Fibroblast Growth Factor 23 (FGF23)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153062_BIOACTIVITY11.jpg Bioactivity (Figure 2. The chemotactic effect of ENA-78 on THP-1 cells)

Epithelial Neutrophil Activating Peptide 78 (ENA78), Active Protein (Cat# AAA153062)

Full Name
Active Epithelial Neutrophil Activating Peptide 78 (ENA78)
Gene Names
CXCL5; SCYB5; ENA-78
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153073_BIOACTIVITY13.jpg Bioactivity (Neurosecretory protein VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. Human VGF precursor is 615 amino acids (aa) in length. It contains an 22 aa signal sequence plus a 593 aa mature re)

VGF Nerve Growth Factor Inducible (VGF), Active Protein (Cat# AAA153073)

Full Name
Active VGF Nerve Growth Factor Inducible (VGF)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153081_BIOACTIVITY13.jpg Bioactivity (Perforin 1 (PRF1) is a pore forming cytolytic protein found in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Upon degranulation, perforin binds to the target cell's plasma membrane, and oligomerises in a Ca2 dependent manner to form pores o)

Perforin 1 (PRF1), Active Protein (Cat# AAA153081)

Full Name
Active Perforin 1 (PRF1)
Gene Names
Prf1; Cyta; RATCYTA
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA153091_BIOACTIVITY13.jpg Bioactivity (Interleukin 3 receptor alpha (IL3Ra), also known as CD123 (Cluster of Differentiation 123), is a subunit of the functional high-affinity mouse IL-3 receptor which is a heterodimer. The alpha subunit alone binds IL-3 with low affinity. The beta subunit doe)

Interleukin 3 Receptor Alpha (IL3Ra), Active Protein (Cat# AAA153091)

Full Name
Active Interleukin 3 Receptor Alpha (IL3Ra)
Gene Names
Il3ra; CD123; SUT-1; CDw123
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153103_WB8.jpg WB (Western Blot) (Sample: Recombinant S100A9, Human;Antibody: Rabbit Anti- Human S100A9 Ab)

S100 Calcium Binding Protein A9 (S100A9), Active Protein (Cat# AAA153103)

Full Name
Active S100 Calcium Binding Protein A9 (S100A9)
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA152953_BIOACTIVITY11.jpg Bioactivity (Figure 2. Inhibition of A549 cells proliferation after stimulated with recombinant mouse IFN-alpha.)

Interferon Alpha (IFNa), Active Protein (Cat# AAA152953)

Full Name
Active Interferon Alpha (IFNa)
Gene Names
Ifna1; Ifa1
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA152960_BIOACTIVITY11.jpg Bioactivity (Figure 2. Cell proliferation of TF-1 cells after stimulated with GM-CSF.)

Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF), Active Protein (Cat# AAA152960)

Full Name
Active Colony Stimulating Factor 2, Granulocyte Macrophage (GM-CSF)
Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA152969_BIOACTIVITY11.jpg Bioactivity (Figure 2. The dose-effect curve of IL-3 on TF-1 cells)

Interleukin 3 (IL3), Active Protein (Cat# AAA152969)

Full Name
Active Interleukin 3 (IL3)
Gene Names
Il3; BPA; PSF; HCGF; Il-3; MCGF; Csfmu
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
product-image-AAA152973_BIOACTIVITY13.jpg Bioactivity (Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.Thus, chemotaxis assay used 24-well microchemotaxis syste)

Interleukin 8 (IL8), Active Protein (Cat# AAA152973)

Full Name
Active Interleukin 8 (IL8)
Gene Names
CXCL8; IL8
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA152976_BIOACTIVITY13.jpg Bioactivity (Monocyte Chemotactic Protein 1 (MCP1), also known as C-C motif chemokine 2(CCL2), is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils. Rat CCL2 is secreted as a 14 kDa glycoprotein monomer but noncov)

Monocyte Chemotactic Protein 1 (MCP1), Active Protein (Cat# AAA152976)

Full Name
Active Monocyte Chemotactic Protein 1 (MCP1)
Gene Names
Ccl2; MCP-1; Scya2; Sigje
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA152980_BIOACTIVITY13.jpg Bioactivity (Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide r)

Superoxide Dismutase 3, Extracellular (SOD3), Active Protein (Cat# AAA152980)

Full Name
Active Superoxide Dismutase 3, Extracellular (SOD3)
Gene Names
Sod3; EC-SOD; AI314465
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA152989_BIOACTIVITY11.jpg Bioactivity (Figure 2. Inhibition of A549 cells proliferation after stimulated with TNFalpha)

Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA152989)

Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
TNF; TNF-alpha
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA152994_BIOACTIVITY13.jpg Bioactivity (Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFalpha, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. The primary role of TNF)

Tumor Necrosis Factor Alpha (TNFa), Active Protein (Cat# AAA152994)

Full Name
Active Tumor Necrosis Factor Alpha (TNFa)
Gene Names
TNF; TNF-ALPHA
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA152997_BIOACTIVITY13.png Bioactivity (Thrombopoietin (TPO) is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis.TPO can promote platelet production, aggregation, ECM adhesion, and activation. It is principally produced in t)

Thrombopoietin (TPO), Active Protein (Cat# AAA152997)

Full Name
Active Thrombopoietin (TPO)
Gene Names
Thpo; Ml; Tpo; Mgdf; Tpo1; Tpo2; Tpo3; Tpo4; Mpllg
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA152999_BIOACTIVITY13.jpg Bioactivity (Plasminogen Activator, Urokinase Receptor (uPAR) is the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasmi)

Plasminogen Activator, Urokinase Receptor (uPAR), Active Protein (Cat# AAA152999)

Full Name
Active Plasminogen Activator, Urokinase Receptor (uPAR)
Gene Names
Plaur; Par; uPAR; Plaur3; uPAR-2; uPAR-3
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153002_BIOACTIVITY11.jpg Bioactivity (Figure 2. Cell apoptosis of A549 cells after stimulated with recombinant dog IFNb.)

Interferon Beta (IFNb), Active Protein (Cat# AAA153002)

Full Name
Active Interferon Beta (IFNb)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
product-image-AAA153005_BIOACTIVITY11.jpg Bioactivity (Figure 2. Cell apoptosis of A549 cells after stimulated with IFNb.)

Interferon Beta (IFNb), Active Protein (Cat# AAA153005)

Full Name
Active Interferon Beta (IFNb)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153026_BIOACTIVITY13.jpg Bioactivity (Galectin 9 (GAL9) is a member of the beta-galactoside-binding galectin family. Galectin-9 is found outside of cells and may be exported by non-classical pathways. Galectin 9 exhibits a variety of biological activities, the majority of which have focused o)

Galectin 9 (GAL9), Active Protein (Cat# AAA153026)

Full Name
Active Galectin 9 (GAL9)
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153030_BIOACTIVITY13.jpg Bioactivity (Galectin-6(GAL6) is a protein that in humans is encoded by the LGALS6 gene. The galectins constitute a large family of carbohydrate-binding proteins with specificity for N-acetyl-lactosamine-containing glycoproteins. At least 14 mammalian galectins, which)

Galectin 6 (GAL6), Active Protein (Cat# AAA153030)

Full Name
Active Galectin 6 (GAL6)
Gene Names
Lgals6; galectin-6
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA153032_BIOACTIVITY11.jpg Bioactivity (Figure 2. The hemagglutination assay of GAL1 in V- bottom shaped 96-well microtiter plate.)

Galectin 1 (GAL1), Active Protein (Cat# AAA153032)

Full Name
Active Galectin 1 (GAL1)
Gene Names
LGALS1; GBP; GAL1
Applications
Activity Assay, Cell Culture
Purity
Greater than 97% by SDS-PAGE
Pricing
product-image-AAA243725_BIOACTIVITY13.jpg Bioactivity

B-Cell Receptor CD22 (CD22), Active Protein (Cat# AAA243725)

Full Name
Recombinant Human B-Cell Receptor CD22 (CD22), Partial (Active)
Gene Names
CD22; SIGLEC2; SIGLEC-2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA243734_BIOACTIVITY13.jpg Bioactivity

Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17), Active Protein (Cat# AAA243734)

Full Name
Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17), Partial (Active)
Gene Names
TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
product-image-AAA258260_AD13.png Application Data (Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-10 ug/mL in the presence of 500 ng/mL recombinant human BMP2.)

DLL1, Active Protein (Cat# AAA258260)

Full Name
DLL1 Protein, Rat, Recombinant (His Tag)
Purity
>65% as determined by SDS-PAGE
Pricing
product-image-AAA257951_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human CD155a-His at 10ug/mL (100uL/well) can bind human TIGIT-Fc, the EC50 of human TIGIT-Fc is 0.03-0.2ug/mL.)

TIGIT, Active Protein (Cat# AAA257951)

Full Name
TIGIT Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
TIGIT; VSIG9; VSTM3; WUCAM
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257883_AD13.png Application Data (Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. The ED50 for this effect is 2.5-10 ug/mL.)

BMPR1A/ALK-3, Active Protein (Cat# AAA257883)

Full Name
BMPR1A/ALK-3 Protein, Human, Recombinant (His Tag)
Gene Names
BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del
Purity
>85% as determined by SDS-PAGE
Pricing
product-image-AAA257933_AD13.png Application Data (Measured by its ability to inhibit FGF-acidic (aFGF/FGF1) dependent proliferation of Balb/C 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.5-2.5 ng/ml.)

FGFR2, Active Protein (Cat# AAA257933)

Full Name
FGFR2 Protein, Human, Recombinant (His & hFc Tag)
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Purity
>90% as determined by SDS-PAGE
Pricing
product-image-AAA257938_SDS_PAGE15.jpg SDS-PAGE

Hemopexin, Active Protein (Cat# AAA257938)

Full Name
Hemopexin Protein, Human, Recombinant (His Tag)
Gene Names
HPX; HX
Purity
>96% as determined by SDS-PAGE
Pricing
product-image-AAA214310_AD13.png Application Data

GM-CSF (CSF2), Active Protein (Cat# AAA214310)

Full Name
Recombinant Mouse GM-CSF (CSF2)
Gene Names
Csf2; CSF; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214316_AD13.png Application Data

IL2, Active Protein (Cat# AAA214316)

Full Name
Recombinant Mouse IL2
Gene Names
Il2; Il-2
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214332_AD13.png Application Data

LIX (CXCL5), Active Protein (Cat# AAA214332)

Full Name
Recombinant Mouse LIX (CXCL5)
Gene Names
Cxcl5; LIX; Cxcl6; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214334_AD13.png Application Data

FGF8, Active Protein (Cat# AAA214334)

Full Name
Recombinant Mouse FGF8
Gene Names
FGF8; HH6; AIGF; KAL6; FGF-8; HBGF-8
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA214336_AD13.png Application Data

CNTF, Active Protein (Cat# AAA214336)

Full Name
Recombinant Rat CNTF
Purity
>95% as determined by SDS-PAGE
Pricing

BTK, Active Protein (Cat# AAA214345)

Full Name
Recombinant Human BTK (N-His tag)
Reactivity
Human (H. sapiens)
Pricing
product-image-AAA148221_SDS_PAGE13.jpg SDS-PAGE

Interleukin 2 (IL2), Active Protein (Cat# AAA148221)

Full Name
Active Interleukin 2 (IL2)
Gene Names
IL2; IL-2; TCGF; lymphokine
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
product-image-AAA150058_AD13.jpg Application Data (Figure. Cell proliferation of Jurkat cells after stimulated with IL1a.Interleukin 1 alpha (IL1) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. IL1 is produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. It is on the pathway that activates tumor necrosis factor-alpha. To test the effect of IL1a on cell proliferation, Jurkat cells were seeded into triplicate wells of 96-well plates at a density of 2,000 cells/well with 2% serum standard 1640 including various concentrations of recombinant human IL1a. After incubated for 96h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37. Proliferation of Jurkat cells after incubation with IL1a for 96h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8) assay after incubation with recombinant IL1a for 96h. The result was shown in Figure 2. It was obvious that IL1a significantly increased cell viability of Jurkat cells.(A) Jurkat cells cultured in 1640, stimulated with 10ng/mL IL1a for 96h; (B) Unstimulated Jurkat cells cultured in1640 for 96h.)

Interleukin 1 Alpha, Active Protein (Cat# AAA150058)

Full Name
Active Interleukin 1 Alpha (IL1a)
Gene Names
IL1A; IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
product-image-AAA150072_SDS_PAGE10.png SDS_PAGE (Sample: Active recombinant SOD3, Human)

Superoxide Dismutase 3, Extracellular, Active Protein (Cat# AAA150072)

Full Name
Active Superoxide Dismutase 3, Extracellular (SOD3)
Gene Names
SOD3; EC-SOD
Reactivity
Homo sapiens (Human)
Applications
Activity Assay, Cell Culture
Purity
>90%
Pricing
product-image-AAA150093_AD10.jpg Application Data (IL-1 (Interleukin-1 beta) is a proinflammatory and immunoregulatory cytokine involved in a variety of cellular activities. It has been elucidated that IL-1 stimulation of cells activates MMP-9 (matrix metalloproteinases-9) secretion by the activation of the dual signalling pathways. Thus, a stimulation assay of IL-1 was conducted using 3T3 cell line, and the MMP-9 activity was detected through gel zymography. Briefly, 1×106 3T3 cells were cultured overnight in 5%DMEM, washed with serum-free medium and then stimulated with different concentrations of IL-1 for 20h, and cell lysates were collected to measure MMP-9 activity. Cell lysates samples were denatured by SDS loading buffer, electrophoresed through sodium dodecyl sulphate–polyacrylamide gel (SDS–PAGE; 10% gels) containing gelatin (1mg/mL) with nonreducing conditions. After renaturation, incubation and coomassiebrilliant blue (CBB)-stained, MMPs hydrolyzed gelatin nearby, indicated by the white binds on the gel. Result Increased MMP-9 activity in 3T3 cells due to the stimulation of IL-1 was shown in Figure 1.Figure. Activation of MMP-9 by IL-1.)

Interleukin 1 Beta, Active Protein (Cat# AAA150093)

Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
Il1b; Il-1b; IL-1beta
Applications
Activity Assay, Cell Culture
Purity
>97%
Pricing
product-image-AAA150109_AD11.jpg Application Data (Figure. Cell proliferation of spleen cells after stimulated with GP39.)

Chitinase-3-like Protein 1, Active Protein (Cat# AAA150109)

Full Name
Active Chitinase-3-like Protein 1 (CHI3L1)
Gene Names
Chi3l1; Chil1; GP-39; CGP-39
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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