Filters
▼Clonality
▼Type
▼Reactivity
▼Gene Name
▼Isotype
▼Host
▼Application
▼Clone
▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 1650-1700 of 2875 product results
Bioactivity
(HTRF Assay for Recombinant PRKD2 activity. 1 uM STK S1 substrate was incubated with different concentrations of PRKD2 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Thioredoxin-1, Active Protein (Cat# AAA48313)
Full Name
Recombinant Thioredoxin-1
Gene Names
Txn1; ADF; Txn; Trx1; AW550880
Applications
Enzyme Activity, SDS-PAGE
Purity
>90% by SDS-PAGE
Pricing
Application Data
Fibronectin Type III Domain Containing Protein 5 (FNDC5), Active Protein (Cat# AAA146625)
Full Name
Active Fibronectin Type III Domain Containing Protein 5 (FNDC5)
Gene Names
FNDC5; FRCP2; irisin
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Bioactivity
(Figure. Cell suppresstion of HepG2 cells after stimulated with SFRP1.)
Secreted Frizzled Related Protein 1, Active Protein (Cat# AAA150141)
Full Name
Active Secreted Frizzled Related Protein 1 (SFRP1)
Gene Names
Sfrp1; sFRP-1
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Bioactivity
(EphrinB2 (EFNB2), a 40 kDa member of the EphrinB family, is a pivotal bidirectional signaling molecule ubiquitously expressed in mammals and is crucial in angiogenesis during development and disease progression. Besides, EFNB2 is expressed at abnormally high levels in some neoplasms, such as squamous cell carcinoma of the head and neck and colorectal cancer. Its overexpression is associated with the malignant progression of tumors. Reelin (RELN) has been identified as an interactor of EFNB2, thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human EFNB2 and recombinant human RELN. Briefly, EFNB2 was diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to RELN-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-EFNB2 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody for 1h at 37 degree C, wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 uL stop solution to the wells and read at 450/630 nm immediately. The binding activity of recombinant human EFNB2 and recombinant human RELN was shown in Figure 1, the EC50 for this effect is 0.02 ug/mL.)
Ephrin B2 (EFNB2), Active Protein (Cat# AAA161920)
Full Name
Active Ephrin B2 (EFNB2)
Gene Names
EFNB2; HTKL; EPLG5; Htk-L; LERK5
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
IL1A, Active Protein (Cat# AAA214229)
Full Name
Recombinant Human IL1A
Gene Names
IL1A; IL1; IL-1A; IL1F1; IL1-ALPHA
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
RANTES (CCL5), Active Protein (Cat# AAA214251)
Full Name
Recombinant Human RANTES (CCL5)
Gene Names
CCL5; SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.6-3 ug/mL in the presence of 10 ng/ml Recombinant Human Activin A.)
ACVR2A, Active Protein (Cat# AAA258185)
Full Name
ACVR2A Protein, Mouse, Recombinant (His Tag)
Gene Names
Acvr2a; Acvr2; ActrIIa; TactrII
Purity
>97% as determined by SDS-PAGE
> 95% as determined by SEC-HPLC
> 95% as determined by SEC-HPLC
Pricing
Application Data
(Immobilized human ACE2 protein (Fc tag)(Cat: 10108-H05H) at 2 ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 (BA.2.12.1) Spike S1+S2 trimer Protein(ECD,His&AVI Tag)(Cat: AAA258593), the EC50 is 3-10 ng/mL.)
COVID 19 (BA.2.12.1) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258593)
Full Name
SARS-CoV-2 (BA.2.12.1) Spike S1+S2 trimer Protein (ECD, His & AVI Tag), Biotinylated
Purity
>90% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human EFNA1-His at 10 ug/ml (100 ul /well) can bind human EPHA1-Fc, The EC50 of human EPHA1-Fc is 10-30 ng/ml.)
EphA1, Active Protein (Cat# AAA258037)
Full Name
EphA1 Protein, Human, Recombinant (hFc Tag)
Gene Names
EPHA1; EPH; EPHT; EPHT1
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized Human ACE2 (mFc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G)-His is 15-90 ng/mL.)
COVID 19 Spike S1(K417N, E484K, N501Y, D614G)-His Coronavirus, Active Protein (Cat# AAA258087)
Full Name
SARS-CoV-2 (2019-nCoV) Spike S1(K417N, E484K, N501Y, D614G)-His Recombinant Protein
Purity
>90% as determined by SDS-PAGE
Pricing
Bioactivity
(HTRF Assay for Recombinant PDGFRA (550-1089) activity. 1 uM TK substrate was incubated with different concentrations of PDGFRA (550-1089) protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 5 nM SEB and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
PDGFRA, Active Protein (Cat# AAA60339)
Full Name
Recombinant PDGFRA (550-1089) protein
Purity
>85%
Pricing
Application Data
(The purity of SARS-COV-2 Spike S1 Protein with His tag (Cat.AAA281532) was greater than 90% as determined by SEC-HPLC.)
COVID 19 Spike S1 Coronavirus, Active Protein (Cat# AAA281532)
Full Name
Recombinant 2019-nCoV Spike S1 Protein with His tag
Purity
> 90% by SDS-PAGE.
Pricing
SDS-PAGE
Fibroblast Growth Factor 21 (FGF21), Active Protein (Cat# AAA149261)
Full Name
Active Fibroblast Growth Factor 21 (FGF21)
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
SDS-PAGE
(Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.)
BCMA, Active Protein (Cat# AAA47216)
Full Name
Recombinant human BCMA protein with C-terminal mouse Fc tag
Gene Names
TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
Applications
Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Pricing
Application Data
VEGFR-2/KDR (native), soluble, Active Protein (Cat# AAA79129)
Full Name
Human VEGFR-2/KDR (native), soluble
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Alkaline Phosphatase Placental, Active Protein (Cat# AAA38066)
Full Name
Recombinant Human Alkaline Phosphatase Placental, BioActive
Gene Names
ALPP; ALP; PALP; PLAP; PLAP-1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
Application Data
IL13, Active Protein (Cat# AAA214231)
Full Name
Recombinant Human IL13
Gene Names
IL13; P600; IL-13
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
IFNA2, Active Protein (Cat# AAA214269)
Full Name
Recombinant Human IFNA2
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
>95% as determined by SDS-PAGE
Pricing
Bioactivity
(Tissue kallikreins are a family of extracellular serine proteases consisting of 15 members. Tissue kallikreins have attracted great interest as potential biomarkers for various cancers, including prostate, ovarian, breast, testicular, and lung. Human Kallikrein 6 (hKLK6) is a member of tissue kallikrein family observed in breast and brain tissues, colon carcinoma cells, and oligodedrocytes. Known protein substrates of hKLK6 are myelin basic protein, the precursor of the A beta amyloid peptide, and plasminogen. Its physiological functions may include the participation in demyelination processes as well as in the progression of inflammatory disease of the CNS. The activity assay of recombinant mouse KLK6 was measured by its ability to cleave the fluorogenic peptide substrate Boc-QAR-AMC. The rmKLK6 was activated by Lysyl-endopeptidase in the activation buffer 50 mM Tris, 0.05% (w/v) Brij-35, pH 8.0, of which equal volumes of 200 ug/ml rmKLK6 and 2.5 mU/ml Lysyl-endopeptidase were combined and incubated at room temperature for 30 minutes. The activated rmKLK6 was diluted to 3 ug/ml in assay buffer and start the reaction by adding 50 uL of 200 uM substrate. Read at excitation and emission wavelengths of 380 nm and 460 nm (top read), respectively, in kinetic mode for 5 minutes. The specific activity of recombinant mouse KLK6 is >6000 pmol/min/ug.)
Kallikrein 6 (KLK6), Active Protein (Cat# AAA161769)
Full Name
Active Kallikrein 6 (KLK6)
Gene Names
Klk6; BSP; MSP; Bssp; Klk29; Prss9; Prss18; AI849898; neurosin
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
COVID 19 (BA.2.75) Spike S1+S2 trimer Coronavirus, Active Protein (Cat# AAA258580)
Full Name
SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein (ECD, His Tag)
Purity
>95% as determined by SDS-PAGE. >95% as determined by SEC-HPLC.
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized Human CD21 His at 2 ug/ml (100 ul/well) can bind Human Annexin VI/ANXA6 His, Biotinylated, the EC50 of Human Annexin VI/ANXA6 His, Biotinylated is 250-900 ng/mL.)
CD21, Active Protein (Cat# AAA257931)
Full Name
CD21 Protein, Human, Recombinant (His Tag)
Gene Names
CR2; CR; C3DR; CD21; CVID7; SLEB9
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit TNF-alpha mediated cytotoxicity in L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically2-10ng/mL in the presence of 0.25 ng/mL recombinant human TNF-alpha.)
TNFRSF1A, Active Protein (Cat# AAA257939)
Full Name
TNFRSF1A Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
TNFRSF1A; FPF; MS5; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55; TNFR1-d2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized Human TGF-alpha at 2 ug/ml (100 ul/well) can bind Human EGFR hFc, the EC50 of Human EGFR hFc is 80-500 ng/mL.)
TGF-alpha, Active Protein (Cat# AAA257972)
Full Name
TGF-alpha Protein, Human, Recombinant
Gene Names
TGFA; TFGA
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 1-4 ug/mL.)
CNTF, Active Protein (Cat# AAA257994)
Full Name
CNTF Protein, Human, Recombinant (His Tag)
Gene Names
CNTF; HCNTF
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized Human EphA2 His at 2 ug/ml (100 ul/well) can bind Human Ephrin-A1 His & hFc, the EC50 of Human Ephrin-A1 His & hFc is 4.0-20.0 ng/mL.)
EphA2, Active Protein (Cat# AAA258029)
Full Name
EphA2 Protein, Human, Recombinant (His Tag)
Gene Names
EPHA2; ECK; CTPA; ARCC2; CTPP1; CTRCT6
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human PD-L2 at 2 ug/ml (100 ul/well) can bind human PD-1, the EC50 of human PD-1 is 150-800 ng/mL.)
PD-L2, Active Protein (Cat# AAA257866)
Full Name
PD-L2 Protein, Human, Recombinant (ECD, His Tag)
Gene Names
PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2
Purity
>98% as determined by SDS-PAGE
Pricing
Application Data
(Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts.The ED50 for this effect is typically 0.4-2ng/mL.)
HB-EGF, Active Protein (Cat# AAA257870)
Full Name
HB-EGF Protein, Human, Recombinant
Gene Names
HBEGF; DTR; DTS; DTSF; HEGFL
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to bind with uPA-His in a functional ELISA.)
uPAR/PLAUR, Active Protein (Cat# AAA258135)
Full Name
uPAR/PLAUR Protein, Mouse, Recombinant (His Tag)
Gene Names
Plaur; Cd87; uPAR; u-PAR
Purity
>97% as determined by SDS-PAGE
Pricing
Bioactivity
(Wingless-type MMTV integration site family, member 16 is a protein that in humans is encoded by the WNT16 gene. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It contains two transcript variants diverging at the 5 termini. These two variants are proposed to be the products of separate promoters and not to be splice variants from a single promoter. Besides, Tubulin Beta 3 (TUBb3) has been identified as an interactor of WNT16, thus a binding ELISA assay was conducted to detect the interaction of recombinant human WNT16 and recombinant human TUBb3. Briefly, WNT16 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100L were then transferred to TUBb3-coated microtiter wells and incubated for 2h at 37. Wells were washed with PBST and incubated for 1h with anti-WNT16 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of WNT16 and TUBb3 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of WNT16 with TUBb3.)
Wingless Type MMTV Integration Site Family, Member 16, Active Protein (Cat# AAA150149)
Full Name
Active Wingless Type MMTV Integration Site Family, Member 16 (WNT16)
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
SDS-PAGE
VEGFR2 / Flk-1 / CD309 / KDR, Active Protein (Cat# AAA173577)
Full Name
Recombinant Human VEGFR2 / Flk-1 / CD309 / KDR Protein (His tag)
Gene Names
KDR; FLK1; CD309; VEGFR; VEGFR2
Purity
> 97 % as determined by SDS-PAGE
Pricing
Application Data
(Image: HGF Structure and Sequence.)
Hepatocyte Growth Factor, Active Protein (Cat# AAA76541)
Full Name
Recombinant Human Hepatocyte Growth Factor CHO
Reactivity
Human
Purity
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis bySDS-PAGE.
(a) Analysis by RP-HPLC.
(b) Analysis bySDS-PAGE.
Pricing
Application Data
Nerve Growth Factor (NGF), Active Protein (Cat# AAA146613)
Full Name
Active Nerve Growth Factor (NGF)
Gene Names
MMP8; HNC; CLG1; MMP-8; PMNL-CL
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
Growth Differentiation Factor 9 (GDF9), Active Protein (Cat# AAA148170)
Full Name
Active Growth Differentiation Factor 9 (GDF9)
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 90%
Pricing
Bioactivity
(Bone Morphogenetic Protein Receptor 2 (BMPR2) is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR2 is a TGFbeta type II receptor expressed on cumulus cells. Growth Differentiation Factor 9 (GDF9) can bind to BMPR2 through different type I receptors, thereby regulating downstream metabolic reactions. Thus a functional binding ELISA assay was conducted to detect the interaction of recombinant human BMPR2 and recombinant human GDF9. Briefly, biotin-linked BMPR2 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100 ul were then transferred to GDF9-coated microtiter wells and incubated for 1h at 37 degree C. Wells were washed with PBST 3 times and incubation with Streptavidin-HRP for 30min, then wells were aspirated and washed 5 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50 ul stop solution to the wells and read at 450 nm immediately. The binding activity of recombinant human BMPR2 and recombinant human GDF9 was shown in Figure 1, the EC50 for this effect is 42.87 ng/mL.)
Bone Morphogenetic Protein Receptor 2 (BMPR2), Active Protein (Cat# AAA161656)
Full Name
Active Bone Morphogenetic Protein Receptor 2 (BMPR2)
Gene Names
BMPR2; BMR2; PPH1; BMPR3; BRK-3; T-ALK; BMPR-II
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
BAFF-R (TNFRSF13C), Active Protein (Cat# AAA214211)
Full Name
Recombinant Human BAFF-R (TNFRSF13C)
Gene Names
TNFRSF13C; BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Eotaxin (CCL11), Active Protein (Cat# AAA214217)
Full Name
Recombinant Human Eotaxin (CCL11)
Gene Names
CCL11; SCYA11
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells.The ED50 for this effect is typically 25-100 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.)
Endoglin/CD105, Active Protein (Cat# AAA258161)
Full Name
Endoglin/CD105 Protein, Mouse, Recombinant (His Tag)
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 1-5 ug/mL in the presence of 500 ng/mL recombinant human BMP2.)
DLL4, Active Protein (Cat# AAA258190)
Full Name
DLL4 Protein, Mouse, Recombinant (His Tag)
Gene Names
Dll4; Delta4
Purity
>96% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human GFRA1-Fc at 10 ug/mL (100 uL/well) can bind GDNF/Biotin, the EC50 of human GDNF/Biotin is 20-50 ng/mL.)
GFR Alpha-1/GFRA1, Active Protein (Cat# AAA257871)
Full Name
GFR Alpha-1/GFRA1 Protein, Human, Recombinant (hFc Tag)
Gene Names
GFRA1; GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1
Purity
>90% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to inhibit rhIFN-gamma mediated protection of WISH cells infected with vesicular stomatitis virus(VSV). The ED50 for this effect is typically 2-8 ug/mL.)
IFNGR1, Active Protein (Cat# AAA257873)
Full Name
IFNGR1 Protein, Human, Recombinant (His Tag)
Gene Names
IFNGR1; CD119; IFNGR
Purity
>97% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to induce alkaline phosphatase production by C3H10T1/2 mouse embryonic fibroblast cells. Nakamura, T. et al. (1997) Biochem. Biophys. Res. Commun.237:465. The ED50 for this effect is typically 2-10 ug/mL.)
Sonic Hedgehog, Active Protein (Cat# AAA257878)
Full Name
Sonic Hedgehog Protein, Human, Recombinant (aa 1-197, His Tag)
Gene Names
SHH; TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.4-3 ug/mL in the presence of 10 ng/mL recombinant Activin A.)
ACVR2A, Active Protein (Cat# AAA257857)
Full Name
ACVR2A Protein, Human, Recombinant (His Tag)
Gene Names
ACVR2A; ACVR2; ACTRII
Purity
>97% as determined by SDS-PAGE
Pricing
Bioactivity
(HTRF assay for MST2 activity 1 uM STK S3 substrate was incubated with different concentrations of MST2 protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 10 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Application Data
(Inhibition of FGF10-induced proliferation of 4MBr-5 cells by recombinant human soluble FGFR-2(IIIb)/Fc. sFGFR-2(IIIc)/Fc which do not bind FGF10 show no effect.)
FGFR-2(IIIb)/Fc Chimera, Active Protein (Cat# AAA79321)
Full Name
Recombinant Human Soluble FGFR-2(IIIb)Fc Chimera
Gene Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
Purity
> 90% by SDS-PAGE & silver stain
Pricing
Sequence
Fibrillin 1, Active Protein (Cat# AAA150097)
Full Name
Active Fibrillin 1 (FBN1)
Applications
Activity Assay, Cell Culture
Purity
>98%
Pricing
Application Data
Cluster Of Differentiation 276 (CD276), Active Protein (Cat# AAA148179)
Full Name
Active Cluster Of Differentiation 276 (CD276)
Gene Names
CD276; B7H3; B7-H3; B7RP-2; 4Ig-B7-H3
Reactivity
Human
Applications
Activity Assay, Cell Culture
Purity
> 97%
Pricing
Application Data
IL-4, Active Protein (Cat# AAA79122)
Full Name
Human IL-4
Gene Names
IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Reactivity
Human
Purity
> 98% by SDS-PAGE & silver stain
Pricing
Application Data
(Functional ELISA to test the binding of sTIE-2 to its ligand Ang-2. Ang-2 was coated on the plate and increasing amounts of recombinant human soluble sTIE-2 was added.)
TIE-2, soluble, Active Protein (Cat# AAA79167)
Full Name
Human TIE-2, soluble
Gene Names
TEK; TIE2; VMCM; TIE-2; VMCM1; CD202B
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Pricing
Adiponectin Trimeric Form, Active Protein (Cat# AAA38123)
Full Name
Recombinant Human Adiponectin Trimeric Form
Gene Names
ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.