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Active Proteins

AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.


Viewing 350-400 of 2583 product results


ACE2, Active Protein (Cat# AAA78494)

Full Name
Human ACE2 Protein (Fc Tag)
Purity
>=90% (SDS-PAGE)
Pricing

Adiponectin (ACRP30), Active Protein (Cat# AAA79125)

Full Name
Human Adiponectin (ACRP30)
Gene Names
ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1
Reactivity
Human
Purity
> 98% by SDS-PAGE analyses
Pricing
product-image-AAA60312_BIOACTIVITY11.jpg Bioactivity (HTRF assay for Recombinant SETDB1 protein activity. 1 uM histone peptide H3 (1-21) was incubated with SETDB1 in reaction buffer including 50 mM Tris-HCl pH 8.6, 0.02% Triton X-100, 2 mM MgCl2, 1 mM TCEP and 50 uM SAM for 3 hours at room temperature. H3K9me2 antibody was used to detect reaction product.)

SETDB1, Active Protein (Cat# AAA60312)

Full Name
Recombinant SETDB1 protein
Purity
>85%
Pricing
product-image-AAA60317_BIOACTIVITY11.jpg Bioactivity (HTRF assay for RPS6KA4/RSK4 activity 1 uM STK S3 substrate was incubated with different concentrations of RPS6KA4/RSK4 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 10 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. The detection reagents were added and incubated with the reactions for 30 min. All operations and reactions were performed at room temperature, and HTRF assay was used to detect the enzymatic activity.)

RPS6KA4/RSK4, Active Protein (Cat# AAA60317)

Full Name
Recombinant RPS6KA4/RSK4 protein
Purity
>50%
Pricing
product-image-AAA60328_BIOACTIVITY11.jpg Bioactivity (HTRF Assay for Recombinant NLK activity. 1 uM STK S3 substrate was incubated with different concentrations of NLK protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)

NLK, Active Protein (Cat# AAA60328)

Full Name
Recombinant NLK protein
Purity
>=90%
Pricing
product-image-AAA60334_BIOACTIVITY11.jpg Bioactivity (HTRF assay for PRKCE; activity 11 uM STK S1 substrate was incubated with different concentrations of PRKCE; protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 10 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The detection reagents were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature.)

PRKCE, Active Protein (Cat# AAA60334)

Full Name
Recombinant PRKCE protein
Purity
>=90%
Pricing
product-image-AAA60337_BIOACTIVITY11.jpg Bioactivity (HTRF assay for WNK2 (1-489); activity 1 uM STK S3 substrate was incubated with different concentrations of WNK2 (1-489); protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The detection reagents were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature.)

WNK2, Active Protein (Cat# AAA60337)

Full Name
Recombinant WNK2 (1-489) protein
Purity
>=85%
Pricing
product-image-AAA60340_BIOACTIVITY11.jpg Bioactivity (HTRF Assay for Recombinant PKN2 activity. 1 uM STK S1 substrate was incubated with different concentrations of PKN2 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)

PKN2, Active Protein (Cat# AAA60340)

Full Name
Recombinant PKN2 protein
Purity
>80%
Pricing

Lactate Dehydrogenase 4, Active Protein (Cat# AAA44812)

Full Name
Lactate Dehydrogenase 4 (LDH-4), Human Liver
Pricing

Parathyroid Hormone, Active Protein (Cat# AAA38562)

Full Name
Recombinant Human Parathyroid Hormone (7-34)
Gene Names
PTH1R; PFE; PTHR; PTHR1
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Galectin-3, Active Protein (Cat# AAA38591)

Full Name
Recombinant Human Galectin-3
Gene Names
LGALS3; L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2
Purity
Greater than 97.0% as determined by analysis by SDS-PAGE and HPLC.
Pricing

Interleukin-21, Active Protein (Cat# AAA38193)

Full Name
Recombinant Human Interleukin-21
Gene Names
IL21; Za11; IL-21; CVID11
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing

Noggin, Active Protein (Cat# AAA38222)

Full Name
Recombinant Human Noggin
Gene Names
NOG; SYM1; SYNS1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Interleukin-3, Active Protein (Cat# AAA38225)

Full Name
Recombinant Human Interleukin-3, His Tag
Gene Names
IL3; IL-3; MCGF; MULTI-CSF
Purity
Greater than 90.0% as determined by analysis by SDS-PAGE.
Pricing

Matrix Metalloproteinase-8, Active Protein (Cat# AAA38265)

Full Name
Recombinant Human Matrix Metalloproteinase-8
Gene Names
MMP8; HNC; CLG1; MMP-8; PMNL-CL
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing

Cyclophilin-B, Active Protein (Cat# AAA38273)

Full Name
Recombinant Human Cyclophilin-B
Gene Names
PPIB; OI9; CYPB; SCYLP; CYP-S1; HEL-S-39
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Phosphatase 1A Alpha, Active Protein (Cat# AAA38393)

Full Name
Recombinant Human Protein Phosphatase 1A Alpha Isoform
Gene Names
PPM1A; PP2CA; PP2Calpha; PP2C-ALPHA
Purity
Greater than 95.0% as determined by(a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor receptor-3, Active Protein (Cat# AAA38401)

Full Name
Recombinant Human Vascular Endothelial Growth Factor receptor-3
Gene Names
FLT4; PCL; FLT41; LMPH1A; VEGFR3
Purity
Greater than 90.0% as determined by(a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor receptor-3 Fc Chimera, Active Protein (Cat# AAA38402)

Full Name
Recombinant Human Vascular Endothelial Growth Factor receptor-3 Fc Chimera
Gene Names
FLT4; PCL; FLT41; LMPH1A; VEGFR3
Purity
Greater than 90.0% as determined by(a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Pricing

Endostatin, Active Protein (Cat# AAA38418)

Full Name
Recombinant Human Endostatin
Gene Names
COL18A1; KS; KNO; KNO1
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing

Thioredoxin-2, Active Protein (Cat# AAA38639)

Full Name
Recombinant Human Thioredoxin-2
Gene Names
TXN2; MTRX; TRX2; MT-TRX
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Glutathione S-Transferase pi 1, Active Protein (Cat# AAA38686)

Full Name
Recombinant Human Glutathione S-Transferase pi 1
Gene Names
GSTP1; PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Leptin, Active Protein (Cat# AAA38119)

Full Name
Recombinant Rat Leptin
Gene Names
Lep; OB; obese
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Vascular Endothelial Growth Factor, Active Protein (Cat# AAA38139)

Full Name
Recombinant Rat Vascular Endothelial Growth Factor Related Protein
Gene Names
Vegfa; VPF; Vegf; VEGF-A; VEGF164
Purity
Greater than 90.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Fibroblast Growth Factor-acidic, Active Protein (Cat# AAA38140)

Full Name
Recombinant Human Fibroblast Growth Factor-acidic
Gene Names
FGF1; AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Insulin Like Growth Factor Binding Protein-1, Active Protein (Cat# AAA38149)

Full Name
Human Insulin Like Growth Factor Binding Protein-1
Gene Names
IGFBP1; AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Glial-Derived Neurotrophic Factor, Active Protein (Cat# AAA38153)

Full Name
Recombinant Human Glial-Derived Neurotrophic Factor
Gene Names
GDNF; ATF1; ATF2; HSCR3; HFB1-GDNF
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Prolactin, Active Protein (Cat# AAA38156)

Full Name
Recombinant Mouse Prolactin
Gene Names
Prl; Prl1a1; AV290867
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Flt3-Ligand, Active Protein (Cat# AAA38167)

Full Name
Recombinant Mouse Flt3-Ligand
Gene Names
Flt3l; Ly72L; Flt3lg
Purity
Greater than 98.0% as determined by SDS-PAGE.
Pricing

Interleukin-15, Active Protein (Cat# AAA38169)

Full Name
Recombinant Rat Interleukin-15
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

Desert HedgeHog, Active Protein (Cat# AAA38175)

Full Name
Recombinant Human Desert HedgeHog (C23II)
Gene Names
DHH; GDXYM; HHG-3; SRXY7
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Fibroblast Growth Factor-23, Active Protein (Cat# AAA38181)

Full Name
Recombinant Human Fibroblast Growth Factor-23 His Tag
Gene Names
FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC
Purity
Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Granulocyte Macrophage-Colony Stimulating Factor, Active Protein (Cat# AAA38187)

Full Name
Recombinant Rat Granulocyte Macrophage-Colony Stimulating Factor
Gene Names
Csf2; Gmcsf; Gm-csf
Purity
Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Pricing

Monocyte Chemotactic Protein-1/MCAF, Active Protein (Cat# AAA38081)

Full Name
Recombinant Human Monocyte Chemotactic Protein-1/MCAF (CCL2)
Gene Names
CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Macrophage Inflammatory protein-1 beta, Active Protein (Cat# AAA38083)

Full Name
Recombinant Human Macrophage Inflammatory protein-1 beta (CCL4)
Gene Names
CCL4; ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
Purity
Greater than 99.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Monocyte Chemotactic Protein-3, Active Protein (Cat# AAA38087)

Full Name
Recombinant Human Monocyte Chemotactic Protein-3 (CCL7)
Gene Names
CCL7; FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing

GRO-alpha, Active Protein (Cat# AAA38089)

Full Name
Recombinant Human GRO-alpha (CXCL1)
Gene Names
CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Non-Muscle Myosin-II Regulatory Light Chain, Active Protein (Cat# AAA38457)

Full Name
Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Uracil DNA Glycosylase, Active Protein (Cat# AAA38290)

Full Name
Uracil DNA Glycosylase
Pricing

Interleukin-33, Active Protein (Cat# AAA38972)

Full Name
Recombinant Rat Interleukin-33
Gene Names
Il33; RGD1311155
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Catalase, Active Protein (Cat# AAA38978)

Full Name
Recombinant Human Catalase
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing

Dihydrofolate Reductase, Active Protein (Cat# AAA38726)

Full Name
Recombinant Human Dihydrofolate Reductase
Gene Names
DHFR; DYR; DHFRP1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing

Fibroblast Growth Factor-8, Active Protein (Cat# AAA38889)

Full Name
Recombinant Mouse Fibroblast Growth Factor-8
Gene Names
Fgf8; Aigf; Fgf-8
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing

Parathyroid Hormone, Active Protein (Cat# AAA38891)

Full Name
Recombinant Human Parathyroid Hormone (1-84) N15 Labeled
Gene Names
PTH; PTH1
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
product-image-AAA258033_AD11.png Application Data (Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 1-5 ng/mL.)

VEGF121b, Active Protein (Cat# AAA258033)

Full Name
VEGF121b Protein, Human, Recombinant
Gene Names
VEGFA; VPF; VEGF; MVCD1
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258062_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized human CD47 at 2 ug/ml (100 ul/well) can bind human SIRPa(V2)-His, the EC50 of human SIRPa(V2)-His is 200-800 ng/mL.)

SIRP alpha, Active Protein (Cat# AAA258062)

Full Name
SIRP alpha Protein, Human, Recombinant (ECD, SIRP alphaV2, His Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA258011_AD13.png Application Data (1. Measured by its binding ability in a functional ELISA. Immobilized human CD2-His at 10 ug/ml (100 ul/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.1 ug/ml. 2. Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CD2-His at 10 ug/ml (100 ul/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.10 ug/ml.)

CD58, Active Protein (Cat# AAA258011)

Full Name
CD58 Protein, Human, Recombinant (hFc Tag)
Purity
>95% as determined by SDS-PAGE
Pricing
product-image-AAA257825_AD13.png Application Data (Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.)

ALK-1, Active Protein (Cat# AAA257825)

Full Name
ALK-1 Protein, Human, Recombinant (hFc Tag)
Gene Names
ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Purity
>97% as determined by SDS-PAGE
Pricing
product-image-AAA257849_AD13.png Application Data (Measured by its binding ability in a functional ELISA. Immobilized Inhibin Human, Mouse, Rat, Cynomolgus, Rhesus Inhibin beta A/Activin A at 2 ug/ml (100 ul/well) can bind Human ACVR2B hFc, the EC50 of Human ACVR2B hFc is 12-60 ng/mL.)

ACVR2B, Active Protein (Cat# AAA257849)

Full Name
ACVR2B Protein, Human, Recombinant (ECD, hFc Tag)
Gene Names
ACVR2B; HTX4; ACTRIIB; ActR-IIB
Purity
>97% as determined by SDS-PAGE
Pricing
product-image-AAA258252_AD13.png Application Data (Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 5-15 ng/mL in the presence of 2 ng/mL of recombinant human BMP-9.)

ALK-1, Active Protein (Cat# AAA258252)

Full Name
ALK-1 Protein, Canine, Recombinant (hFc Tag)
Purity
>95% as determined by SDS-PAGE
Pricing

What Are Active Proteins?


Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).


If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.


Key Applications of Active Proteins


1. Scientific Research


  • Aid in the study of how proteins function in the body

  • Aid in understanding various disease processes


2. Drug Development


  • Powerful tools to investigate how potential drugs interact with specific proteins

  • Ideal for identifying drug targets


3. Cell Culture


  • Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)

  • Can be used to promote cellular development into specific types (differentiation)


4. Diagnostics


  • Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)

  • Note: All products are strictly for research-use only (RUO).


5. Therapeutics


  • Some active proteins are used directly as treatments (e.g., insulin, enzymes)

  • Note: All products are strictly for research-use only (RUO).


6. Vaccine Development


  • Used to create or test vaccines by mimicking parts of viruses or bacteria


7. Biochemical Assays


  • They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests


Why Buy Active Proteins from AAA Biotech?


  • High biological activity – Verified to perform as expected or indicated on datasheet

  • Strict quality control – We are confident in our active proteins’ reliability and consistency

  • High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components

  • Freeze-dried for stability – Long shelf life and straightforward storage

  • Mostly tag-free – Closer to natural/native protein form


FAQ


1. What are active proteins used for in research?


Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.


2. How are AAA Biotech's active proteins validated?


AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.


3. Are these proteins tested for biological activity?


Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.


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