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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 150-200 of 2567 product results
Purity Data
(The purity of CD147 was determined to be >90%by densitometry, approx. MW 70 kDa.)
Soluble Fibrin, Active Protein (Cat# AAA37871)
Full Name
Soluble Mouse Fibrin
Gene Names
Fga; Fib
Purity
>95% by SDS-PAGE analysis
Pricing
Purity Data
(Sample Purity Data.)
SDS-PAGE
(SDS-PAGE analysis: Lane 1: MW marker, Lane 2: 1ug TRAIL (soluble) (human), (recombinant) (His-tag) (Prod. No. BML-SE721).)
TRAIL, Active Protein (Cat# AAA77052)
Full Name
TRAIL (soluble) (human), (recombinant) (His-tag)
Gene Names
TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L
Purity
>=95% (SDS-PAGE)
Purified by multi-step chromatography
Purified by multi-step chromatography
Pricing
Purity Info
(The purity of PIP5K1C was detrermined to be >70% by densitometry approx. MW 120 kDa.)
PIP5K1C, Active Protein (Cat# AAA73045)
Full Name
PIP5K1C, Active
Gene Names
PIP5K1C; LCCS3; PIP5Kgamma; PIP5K-GAMMA; PIP5K1-gamma
Purity
>80%
Pricing
Specific Activity
(Sample Activity Plot.)
COVID 19 PLpro Coronavirus, Active Protein (Cat# AAA73170)
Full Name
2019-nCoV PLpro, Active
Pricing
Bioactivity
(HTRF for MRCKa/CDC42BPA (1-473) activity 1 uM STK S3 substrate was incubated with different concentrations of MRCKa/CDC42BPA (1-473) protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. Then 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
MRCKa/CDC42BPA, Active Protein (Cat# AAA60314)
Full Name
Recombinant MRCKa/CDC42BPA (1-473) protein
Purity
>=95%
Pricing
Bioactivity
(HTRF assay for Recombinant MRCKb/CDC42BPB (1-473) protein activity 1 uM STK S3 substrate was incubated with different concentrations of MRCKb/CDC42BPB (1-473) protein in a 10 ul reaction system containing 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. Then 10 ul detection reagents containing anti-STK antibody (1:2) GST and SA-XL665 mixture (each 1:100 diluted with 1X Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
MRCKb/CDC42BPB, Active Protein (Cat# AAA60315)
Full Name
Recombinant MRCKb/CDC42BPB (1-473) protein
Purity
>95%
Pricing
Purity Info
PDE7A, Active Protein (Cat# AAA72929)
Full Name
PDE7A, Active recombinant protein
Gene Names
PDE7A; HCP1; PDE7
Purity
>90%
Pricing
Bioactivity
(HTRF assay for RPS6KB1 activity 1 uM STK S3 substrate was incubated with different concentrations of RPS6KB1 protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 2 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Bioactivity
(HTRF Assay for Recombinant PHKG2 activity. 1 uM STK S1 substrate was incubated with different concentrations of PHKG2 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 10 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Neuron-specific Enolase, Active Protein (Cat# AAA78132)
Full Name
Neuron-specific enolase (NSE)
Gene Names
Eno2; NSE; RNEN3
Applications
ELISA
Purity
Ion-exchange chromatography and gel-filtration.
Pricing
Bioactivity
(HTRF Assay for Recombinant PLK1 activity. 1 uM STK S1 substrate was incubated with different concentrations of PLK1 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
Purity Data
(The purity of CD147 (22-205) was determined to be >90% by densitometry. Approx. MW 30-36 kDa.)
IFN alpha 2, Active Protein (Cat# AAA75395)
Full Name
IFN alpha 2 protein (Monkey)
Gene Names
IFNA2; IFNA; INFA2; IFNA2B; IFN-alphaA
Purity
> 98% pure
Pricing
Fibrinogen, Active Protein (Cat# AAA37779)
Full Name
Human Fibrinogen
Gene Names
FGA; Fib2
Purity
>95% by SDS-PAGE analysis
Pricing
Purity Data
(Sample Purity Data.)
COVID 19 NSP10/NSP16 Methyltransferase Coronavirus, Active Protein (Cat# AAA73168)
Full Name
2019-nCoV NSP10/NSP16 Methyltransferase, Active
Pricing
Cancer Antigen 19-9, Active Protein (Cat# AAA44842)
Full Name
Cancer Antigen 19-9 (CA 19-9), Human
Purity
Highly Purified
Pricing
Application Data
(The purity was determined to be > 95% by densitometry.)
PDE4A, Active Protein (Cat# AAA73103)
Full Name
PDE4A, Active
Gene Names
PDE4A; PDE4; DPDE2; PDE46
Purity
>95%
Pricing
Bioactivity
(HTRF Assay for Recombinant PDGFRB (557-1106 activity. 1 uM TK substrate was incubated with different concentrations of PDGFRB (557-1106) protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM MnCl, 1 mM DTT, 5 nM SEB and 100 uM ATP for 1 hour. Then 10 ul detection reagents containing anti-TK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature.)
PDGFRB, Active Protein (Cat# AAA60333)
Full Name
Recombinant PDGFRB (557-1106) protein
Purity
>50%
Pricing
MMP-7, Active Protein (Cat# AAA77046)
Full Name
MMP-7 (catalytic domain) (human), (recombinant)
Purity
> 95% (SDS-PAGE)
Purified by multi-step chromatography
Purified by multi-step chromatography
Pricing
Rheumatoid Factor (RF), Active Protein (Cat# AAA44877)
Full Name
Rheumatoid Factor (RF) Concentrate - > 25 kIU/mL
Purity
Purified
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
GSTA1, Active Protein (Cat# AAA48584)
Full Name
GSTA1, 1-222aa, Human, E Coli (Bioactivity Validated)
Gene Names
GSTA1; GST2; GTH1; GSTA1-1; GST-epsilon
Applications
Enzyme Activity, SDS-PAGE
Purity
> 90% by SDS-PAGE
Pricing
Granzyme A, Active Protein (Cat# AAA77033)
Full Name
Granzyme A (human), (recombinant)
Gene Names
GZMA; HFSP; CTLA3
Purity
>98% (SDS-PAGE)
Pricing
SDS-PAGE
COVID 19 Spike S1 Protein Coronavirus, Active Protein (Cat# AAA176996)
Full Name
Recombinant 2019-nCoV S1 Protein (mFc Tag)
Purity
>95% as determined by reducing SDS-PAGE.
Pricing
MMP-14, Active Protein (Cat# AAA77047)
Full Name
MMP-14 (catalytic domain) (human), (recombinant)
Purity
Partially purified by single-step affinity chromatography and gel filtration
Pricing
Chymase, Active Protein (Cat# AAA75403)
Full Name
Chymase reagent
Gene Names
CMA1; CYH; MCT1; chymase
Purity
> 95% by SDS-PAGE and gel diffusion
Pricing
Interferon Tau, Active Protein (Cat# AAA75447)
Full Name
Purified recombinant Bovine IFN-Tau protein (Bovine)
Reactivity
Bovine
Purity
>=95% pure
Pricing
ELASTASE, Active Protein (Cat# AAA50496)
Full Name
NATIVE HUMAN ELASTASE (NEUTROPHIL)
Gene Names
ELANE; GE; NE; HLE; HNE; ELA2; SCN1; PMN-E
Applications
Functional Assay
Purity
>95% by SDS PAGE
Pricing
GST T1-1, Active Protein (Cat# AAA71852)
Full Name
GST T1-1, Recombinant Human
Purity
>= 95% as assessed by inspection on a Coomassie Blue-stained SDS-PAGE gel.
Pricing
Rheumatoid Factor (RF), Active Protein (Cat# AAA44876)
Full Name
Rheumatoid Factor (RF) Concentrate - > 5 kIU/mL
Purity
Purified
Purity Data
(Sample Purity Data.)
COVID 19 NSP14 Methyltransferase Coronavirus, Active Protein (Cat# AAA73169)
Full Name
2019-nCoV NSP14 Methyltransferase, Active
Pricing
Purity Data
(Sample Purity Data.)
Creatine Kinase BB (CK-BB) Recombinant, Active Protein (Cat# AAA58337)
Full Name
CK-BB, Recombinant
Gene Names
CKB; B-CK; CKBB
Applications
ELISA
Purity
>95% pure (SDS-PAGE). Purified under non-denaturing conditions.
Pricing
Application Data
(Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 20-80 ng/mL in the presence of 10 ng/mL Recombinant Human Activin A.)
Follistatin, Active Protein (Cat# AAA258012)
Full Name
Follistatin Protein, Human, Recombinant (His Tag)
Gene Names
FST; FS
Purity
>90% as determined by SDS-PAGE
Pricing
PKC-delta, Active Protein (Cat# AAA71848)
Full Name
PKC-delta Standard
Gene Names
PRKCD; MAY1; PKCD; ALPS3; CVID9; nPKC-delta
Applications
Western Blot
Pricing
Complement C3, Active Protein (Cat# AAA75344)
Full Name
Complement C3 protein
Gene Names
C3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
Purity
>95% by SDS-PAGE
Pricing
Complement C5b, 6 complex ag, Active Protein (Cat# AAA75367)
Full Name
Complement C5b, 6 complex protein
Reactivity
Human
Purity
>=98% by SDS-PAGE
Pricing
HSV2 gG2, Active Protein (Cat# AAA75436)
Full Name
HSV2 gG2 protein
Applications
Western Blot
Purity
> 95% pure
Pricing
SDS-PAGE
(The purity of KRAS was determined to be >90% by densitometry. Approx. MW 23kDa.)
STREPTOLYSIN-O, Active Protein (Cat# AAA50417)
Full Name
RECOMBINANT STREPTOLYSIN-O
Applications
ELISA
Pricing
Growth Hormone, Active Protein (Cat# AAA38548)
Full Name
Recombinant Porcine Growth Hormone
Gene Names
GH1; GH
Purity
Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Application Data
(Measured by its ability to promote proliferation of INS-1 cells. The ED50 for this effect is 0.2-1 ng/mL.)
Growth Hormone, Active Protein (Cat# AAA258048)
Full Name
Growth Hormone Protein, Human, Recombinant
Gene Names
GH1; GH; GHN; GH-N; hGH-N; IGHD1B
Purity
>90% as determined by SDS-PAGE
Pricing
HDAC2, Active Protein (Cat# AAA77050)
Full Name
HDAC2 (full-length) (human), (recombinant)
Purity
Partially purified by single-step affinity chromatography and gel filtration
Pricing
HIV1 gp120, Active Protein (Cat# AAA75444)
Full Name
HIV1 gp120 protein
Purity
> 95% by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H)-His, the EC50 of SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H)-His is 10-60 ng/mL.)
COVID 19 Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H)-His Coronavirus, Active Protein (Cat# AAA258088)
Full Name
SARS-CoV-2 (2019-nCoV) Spike S1(HV69-70 deletion, Y144 deletion, N501Y, A570D, D614G, P681H)-His Recombinant Protein
Purity
>90% as determined by SDS-PAGE
Pricing
Bioactivity
(Angiogenin (ANG) was initially purified from serum-free media conditioned by growth of a human adenocarcinoma cell line HT-29 based on its ability to initiate vascularization in the chicken embryo chorioallantoic membrane. A number of other tumor, as well as normal, cell lines can also secrete Angiogenin. In addition, Angiogenin is present in normal human plasma at levels as high as 60-120 ng/mL. Surprisingly, Angiogenin has been found to be a member of the ribonuclease superfamily with approximately 35% sequence similarity at the amino acid level with pancreatic RNase. Angiogenin exhibits ribonucleolytic activity that is distinctly different than that of pancreatic RNase A. The ribonucleolytic activity of Angiogenin toward most RNase A substrates is much lower than that of RNase A. Nevertheless, the ribonucleolytic activity of Angiogenin is essential to its angiogenic activity since inhibition of the Angiogenin RNase activity will also abolish angiogenesis activity. The activity of recombinant mouse ANG was measured by its ribonucleolytic activity toward RNA. The result was shown in figure 1, and the rmANG produces a delta Abs260/ug >1.0 in two hours.)
Angiogenin (ANG), Active Protein (Cat# AAA161648)
Full Name
Active Angiogenin (ANG)
Gene Names
Ang; Ang1; Rnase5; Rnase5a; AI385586
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.