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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 250-300 of 2875 product results
Glucagon receptor (GCGR), Active Protein (Cat# AAA114042)
Full Name
Recombinant Human Glucagon receptor (GCGR), partial
Gene Names
GCGR; GGR; GL-R
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Bioactivity
(Measured by its binding ability in a functional ELISA. Immobilized Human TFRC at 2?g/mL can bind Anti-TFRC recombinant antibody, the EC50 is 3.305-8.220 ng/mL.)
Transferrin receptor protein 1 (TFRC), Active Protein (Cat# AAA279234)
Full Name
Recombinant Human Transferrin receptor protein 1 (TFRC), partial (Active)
Gene Names
TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
IGF-BP2, Active Protein (Cat# AAA79281)
Full Name
Human IGF-BP2
Gene Names
IGFBP2; IBP2; IGF-BP53
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
Bioactivity
(Measured by its binding ability in a functional ELISA. Immobilized Human MAGEA4 at 2 ?g/ml can bind anti-MAGEA4 recombinant antibody, the EC50 is 30.33-43.10 ng/mL.)
Melanoma-associated antigen 4 (MAGEA4), Active Protein (Cat# AAA279219)
Full Name
Recombinant Human Melanoma-associated antigen 4 (MAGEA4)(Active)
Gene Names
MAGEA4; CT1.4; MAGE4; MAGE4A; MAGE4B; MAGE-41; MAGE-X2
Purity
Greater than 90% as determined by SDS-PAGE.
Pricing
Bioactivity
(Fibroblast growth factor 23 or FGF23 is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate and vitamin D metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 decrea)
Fibroblast Growth Factor 23 (FGF23), Active Protein (Cat# AAA153054)
Full Name
Active Fibroblast Growth Factor 23 (FGF23)
Gene Names
FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Application Data
Resistin (RETN), Active Protein (Cat# AAA214252)
Full Name
Recombinant Human Resistin (RETN)
Gene Names
RETN; ADSF; RSTN; XCP1; FIZZ3; RETN1
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured in antiviral assay using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is typically 0.2-1 ng/mL.)
Interferon Gamma, Active Protein (Cat# AAA258198)
Full Name
Interferon Gamma Protein, Mouse, Recombinant (His Tag)
Gene Names
Ifng; Ifg; IFN-g
Purity
>75% as determined by SDS-PAGE
Pricing
Human Phosphoglycerate Mutase B Isozyme, Active Protein (Cat# AAA78964)
Full Name
Human Phosphoglycerate Mutase B Isozyme (rPGAM-B (human))
Purity
Single major band of 29kDa (1 mg protein loaded in SDS-PAGE)
Pricing
Bioactivity
(The cytochrome P450 enzyme CYP2E1 catalyzes the oxidative metabolism of many solvents and other small organic molecules. CYP2E1 is expressed in adult and fetal human liver in addition to extrahepatic tissues such as lung and placenta. Treatment of primary cultures of human hepatocytes with ethanol induces CYP2E1 protein, and this is consistent with the finding that hepatic CYP2E1 protein and mRNA levels are increased in individuals with alcoholism. Although only a few drugs (e.g., acetaminophen have been identified as substrates for CYP2E1, many low molecular weight procarcinogens are activated by this cytochrome P450 (P450). Chlorzoxazone 6-hydroxylation, N-nitrosodimethylamine N-demethylation and p-nitrophenol hydroxylation can be used to measure the catalytic activity of CYP2E1. Thus, the recombinant human CYP2E1 activity was measured by its ability to hydroxylate p-nitrophenol to p-nitrocatechol. The reaction was performed in 50 mM potassium phosphate, pH 7.4 (Assay Buffer), initiated by addition 20 uL of 500 ug/ml CYP2E1 to 10 uL of 5 mM substrate p-nitrophenol and 30 ul of 26 mM NADPH in a total volume of 500 ul. Incubated at 37 degree C for 30min, then read at a wavelength of 535 nm after acidification of the reaction mixture with trichloroacetic acid followed by neutralization using 2 M NaOH.)
Cytochrome P450 2E1 (CYP2E1), Active Protein (Cat# AAA161817)
Full Name
Active Cytochrome P450 2E1 (CYP2E1)
Gene Names
CYP2E1; CPE1; CYP2E; P450-J; P450C2E
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
IL24, Active Protein (Cat# AAA214264)
Full Name
Recombinant Human IL24
Gene Names
IL24; C49A; FISP; MDA7; MOB5; ST16; IL10B
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD-His (N354D) Recombinant Protein (40592-V08H2), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD-His (N354D) Recombinant Protein (40592-V08H2) is 20-50 ng/mL.)
COVID 19 Spike RBD-His (N354D) Coronavirus, Active Protein (Cat# AAA258095)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD-His (N354D) Recombinant Protein
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Prolactin (PRL), Active Protein (Cat# AAA214290)
Full Name
Recombinant Human Prolactin (PRL)
Gene Names
PRL; GHA1
Purity
>95% as determined by SDS-PAGE
Pricing
IL-13 alpha 2 receptor (IL13RA2), Active Protein (Cat# AAA76103)
Full Name
Human IL-13 alpha 2 receptor Recombinant (IL13RA2)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
G-CSF, Active Protein (Cat# AAA79275)
Full Name
Mouse G-CSF
Gene Names
Csf3; Csfg; G-CSF; MGI-IG
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
Bioactivity
(Tissue inhibitors of metalloproteinase 1 (TIMP1) is a member of the family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). TIMP-1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. TIMP-1 inhibits active MMP-mediated proteolysis by forming an N-terminal, non-covalent binary complex with the MMP active site. The activity of recombinant human TIMP1 was measured by its ability to inhibit rhMMP2 cleavage of a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. rhMMP2 was diluted to 100 ug/ml and activated with 1 mM APMA at 37 degree C for 1 hour and rhTIMP1 (MW: 22.2 KD) was diluted to different concentrations with the assay buffer. Mix 8 ul of rhTIMP1 curve dilutions, 12.8 ul of activated rhMMP-2, and 59.2 ul of assay buffer, including a control containing assay buffer and the diluted rhMMP-2 and incubate the reactions for 2 hours at 37 degree C. Loading 50 ul of the incubated mixtures which were diluted five-fold in assay buffer into empty wells of a plate, and start the reaction by adding 50 ul of 20 uM substrate. Include a substrate blank containing 50 ul of assay buffer and 50 ul of 20 uM substrate. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The result was shown in Figure 1 and it was obvious that recombinant human TIMP1 significantly decreased rhMMP2 activity. The inhibition IC50 was )
Tissue Inhibitors Of Metalloproteinase 1 (TIMP1), Active Protein (Cat# AAA161743)
Full Name
Active Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)
Gene Names
TIMP1; EPA; EPO; HCI; CLGI; TIMP
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
ELISA
(Immobilized SARS-CoV-2 S1+S2 ECD(S-ECD) at 2ug/mL (100 uL/well) can bind recombinant Human ACE2 with a linear range of 0.15-3.72 ng/mL.)
COVID 19 Spike S1+S2 ECD (S-ECD) His tag (Wild type, pre-fusion state) Coronavirus, Active Protein (Cat# AAA281564)
Full Name
Recombinant SARS-CoV-2 S1+S2 ECD (S-ECD) Protein with His tag (Wild type, pre-fusion state)
Purity
> 95% by SDSPAGE.
Pricing
Programmed cell death 1 ligand 1 (CD274), Active Protein (Cat# AAA233604)
Full Name
Recombinant Human Programmed cell death 1 ligand 1 (CD274), partial (Active)
Gene Names
CD274; B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
Human Promatrilysin, Active Protein (Cat# AAA78967)
Full Name
Human Promatrilysin (rPro-MMP-7 (human))
Pricing
Cancer Antigen 72-4, Active Protein (Cat# AAA44847)
Full Name
Cancer Antigen 72-4 (CA 72-4), Human
Purity
>= 90% (SDS-PAGE)
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombiant Protein (40592-V08H8), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombiant Protein (40592-V08H8) is 25-60 ng/mL.)
COVID 19 Spike RBD(G476S)-His Coronavirus, Active Protein (Cat# AAA258100)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombinant Protein
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TSLP, Active Protein (Cat# AAA214262)
Full Name
Recombinant Human TSLP
Purity
>95% as determined by SDS-PAGE
Pricing
WB (Western Blot)
(Figure 4. Western Blot Sample: Recombinant TGF-Beta1, Human; Antibody: Rabbit Anti8Human TGF-Beta1 Ab)
Transforming Growth Factor Beta 1 (TGFb1), Active Protein (Cat# AAA148233)
Full Name
Active Transforming Growth Factor Beta 1 (TGFb1)
Gene Names
TGFB1; CED; LAP; DPD1; TGFB; TGFbeta
Applications
Activity Assay
Purity
>98%
Pricing
Bioactivity
(Interleukin 1 beta (IL-1beta) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a member of the interleukin 1 family of cytokines. This cytokine is an important medi)
Interleukin 1 Beta (IL1b), Active Protein (Cat# AAA153048)
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
IL1B; IL1-BETA
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
GDNF family receptor alpha-like (Gfral), Active Protein (Cat# AAA117722)
Full Name
Recombinant Mouse GDNF family receptor alpha-like (Gfral)
Gene Names
Gfral; Gral; AY457637
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
IL-23, Active Protein (Cat# AAA79249)
Full Name
Human IL-23
Gene Names
IL23A; P19; SGRF; IL-23; IL-23A; IL23P19
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing
Insulin receptor (CD220), Active Protein (Cat# AAA76108)
Full Name
Human Insulin receptor Recombinant (CD220)
Purity
>98%, as determined by SDS-PAGE and HPLC
Pricing
Bioactivity
(Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), was originally identified as a component of neutrophil granules. It is a 25 kDa protein existing in monomeric and homo- and heterodimeric forms, the latter as a dimer with human neutrophil gelatinases (MMP-9). Its expression has been observed in most tissues normally exposed to microorganism, and its synthesis is induced in epithelial cells during inflammation. Lipocalin-2 has been implicated in a variety of processes including cell differentiation, tumorigenesis, and apoptosis. Studies indicate that Lipocalin-2 binds a bacterial catecholate sidropore bound to ferric ion such as enterobactin with a subnanomolar dissociation constant (Kd = 0.41 nM). The bound ferric enterobactin complex breaks down slowly in a month into dihydroxybenzoyl serine and dihydroxybenzoic acid (DHBA). It also binds to a ferric DHBA complex with much less Kd values (7.9 nM). The activity assay of recombinant human NGAL was measured by its ability to bind Iron(III) dihydroxybenzoic acid Fe(DHBA)3. The binding of Fe(DHBA)3 results in the quenching of Trp fluorescence in Lipocalin-2. The recombinant human NGAL was diluted to 100 ug/ml in assay buffer (50 mM Tris, 10 mM CaCl2, 150 mM NaCl, pH 7.5). 50 uL of the different concentrations of Fe(DHBA)3 and 50 uL of 100 ug/ml rmNGAL was loaded into the plate. Incubated at room temperature for 30 minutes, then read at excitation and emission wavelengths of 280 nM and 340 nM in endpoint mode. The result was shown in Figure 1, the recombinant human Lipocalin-2 can bind >8 uM of Fe(DHBA)3.)
Neutrophil gelatinase-associated lipocalin (NGAL), Active Protein (Cat# AAA161845)
Full Name
Active Neutrophil gelatinase-associated lipocalin (NGAL)
Applications
Activity Assay, Cell Culture
Purity
Greater than 90% by SDS-PAGE
Pricing
Application Data
FGF18, Active Protein (Cat# AAA214296)
Full Name
Recombinant Human FGF18
Gene Names
FGF18; ZFGF5; FGF-18
Purity
>95% as determined by SDS-PAGE
Pricing
Wnt-7a, Active Protein (Cat# AAA79230)
Full Name
Human Wnt-7a
Reactivity
Human
Purity
>80% by SDS-PAGE & HPLC analysis
Pricing
Insulin, Active Protein (Cat# AAA75422)
Full Name
Insulin protein
Gene Names
INS; IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10
Purity
> 98% (by SDS-PAGE and RP-HPLC)
Pricing
Interleukin-6, Active Protein (Cat# AAA38185)
Full Name
Recombinant Rat Interleukin-6
Gene Names
Il6; ILg6; Ifnb2
Purity
Greater than 95.0% as determined by:
Analysis by RP-HPLC
Analysis by SDS-PAGE
Analysis by RP-HPLC
Analysis by SDS-PAGE
Pricing
Interleukin-2, Active Protein (Cat# AAA38188)
Full Name
Recombinant Porcine Interleukin-2
Gene Names
IL2; IL-2; TCGF; POIL2
Purity
Greater than 96.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing
Application Data
EGF, Active Protein (Cat# AAA214216)
Full Name
Recombinant Human EGF
Gene Names
EGF; URG; HOMG4
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized human ACE2 protein (Fc tag)(10108-H05H) at 2 ug/mL (100 uL/well) can bind SARS-CoV-2 (2019-nCoV) Spike RBD-His (F342L) Recombinant Protein (40592-V08H6), the EC50 of SARS-CoV-2 (2019-nCoV) Spike RBD-His (F342L) Recombinant Protein (40592-V08H6) is 20-50 ng/mL.)
COVID 19 Spike RBD-His (F342L) Coronavirus, Active Protein (Cat# AAA258098)
Full Name
SARS-CoV-2 (2019-nCoV) Spike RBD-His (F342L) Recombinant Protein
Purity
>95% as determined by SDS-PAGE
Pricing
sFRP1, Active Protein (Cat# AAA75573)
Full Name
sFRP1 protein
Gene Names
SFRP1; FRP; FRP1; FrzA; FRP-1; SARP2
Purity
> or = 97% by SDS-PAGE and HPLC
Pricing
TGF-beta RII, Active Protein (Cat# AAA48997)
Full Name
Recombinant human TGF-beta RII protein
Gene Names
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII
Applications
Bioactivity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Bioactivity
(Figure. The binding activity of IL1b with IL1R1.)
Interleukin 1 Beta, Active Protein (Cat# AAA150094)
Full Name
Active Interleukin 1 Beta (IL1b)
Gene Names
Il1b; IL-1F2
Applications
Activity Assay, Cell Culture
Purity
>95%
Pricing
Application Data
(Measured by its binding ability in a functional ELISA. Immobilized mouse CD86 at 20 ug/ml (100 ul/well) can bind mouse CD28 with a linear ranger of 6.4-800 ng/ml.)
CD86, Active Protein (Cat# AAA258125)
Full Name
CD86 Protein, Mouse, Recombinant (His Tag)
Gene Names
Cd86; B7; B70; MB7; B7-2; B7.2; CLS1; Ly58; ETC-1; Ly-58; MB7-2; Cd28l2; TS/A-2
Purity
>92% as determined by SDS-PAGE
Pricing
Application Data
FGF2, Active Protein (Cat# AAA214267)
Full Name
Recombinant Human FGF2
Gene Names
FGF2; BFGF; FGFB; FGF-2; HBGF-2
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
Endothelin 1 (EDN1), Active Protein (Cat# AAA148173)
Full Name
Active Endothelin 1 (EDN1)
Gene Names
Edn1; Et1
Reactivity
Rat
Applications
Activity Assay, Cell Culture
Purity
> 95%
Pricing
Placenta growth factor protein (PGF), Active Protein (Cat# AAA114244)
Full Name
Recombinant Human Placenta growth factor protein (PGF) (Active)
Gene Names
PGF; PGFL; PIGF; PLGF; PlGF-2; D12S1900; SHGC-10760
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
PAI-1, Active Protein (Cat# AAA79255)
Full Name
Human PAI-1
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing
Fibroblast Growth Factor-9, Active Protein (Cat# AAA38196)
Full Name
Recombinant Human Fibroblast Growth Factor-9
Gene Names
FGF9; GAF; FGF-9; SYNS3; HBFG-9; HBGF-9
Purity
Greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
Pricing
Staphylococcal Protein-A, Active Protein (Cat# AAA38452)
Full Name
Recombinant Staphylococcal Protein-A
Purity
Greater than 95.0% as determined by RP-HPLC.
Pricing
Tissue Plasminogen Activator, Active Protein (Cat# AAA76078)
Full Name
Human Tissue Plasminogen Activator Recombinant
Purity
>98%, as determined by SDS-PAGE and HPLC
CD155, Active Protein (Cat# AAA76100)
Full Name
Human CD155 Recombinant
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
Bioactivity
(Tissue Inhibitors of Metalloproteinase 4 (TIMP4) is an enzyme that in humans is encoded by the TIMP4 gene. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. The activity of recombinant rat TIMP4 was measured by its ability to inhibit rhMMP2 cleavage of a fluorogenic peptide substrate MCA-Pro-Leu-Gly-Leu-DPA-Ala-Arg-NH2 in the assay buffer 50 mM Tris, 10 mM CaCl2, 150 mM NaCl, 0.05% (w/v) Brij-35, pH 7.5. rhMMP2 was diluted to 100 ug/ml and activated with 1 mM APMA at 37 degree C for 1 hour and rrTIMP4 (MW: 22.79 KD) was diluted to different concentrations with the assay buffer. Mix 8 ul of rrTIMP4 curve dilutions, 12.8 ul of activated rhMMP-2, and 59.2 ul of assay buffer, including a control containing assay buffer and the diluted rhMMP-2 and incubate the reactions for 2 hours at 37 degree C. Loading 50 ul of the incubated mixtures which were diluted five-fold in assay buffer into empty wells of a plate, and start the reaction by adding 50 ul of 20 uM substrate. Include a substrate blank containing 50 ul of assay buffer and 50 ul of 20 uM substrate. Then read at excitiation and emission wavelengths of 320 nm and 405 nm, respectively, in kinetic mode for 5 minutes. The result was shown in Figure 1 and it was obvious that recombinant rat TIMP4 significantly decreased rhMMP2 activity. The inhibition IC50 was )
Tissue Inhibitors Of Metalloproteinase 4 (TIMP4), Active Protein (Cat# AAA161703)
Full Name
Active Tissue Inhibitors Of Metalloproteinase 4 (TIMP4)
Applications
Activity Assay, Cell Culture
Purity
Greater than 95% by SDS-PAGE
Pricing
Application Data
FGF1, Active Protein (Cat# AAA214210)
Full Name
Recombinant Human FGF1
Gene Names
FGF1; AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
Application Data
TNF, Active Protein (Cat# AAA214253)
Full Name
Recombinant Human TNF
Gene Names
TNF; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha
Purity
>95% as determined by SDS-PAGE
Pricing
VE-Statin/EGFL-7, Active Protein (Cat# AAA79165)
Full Name
Human VE-Statin/EGFL7
Gene Names
EGFL7; NEU1; ZNEU1; VE-STATIN; RP11-251M1.2
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Pricing
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids. They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their recombinant proteins or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it will typically display high fidelity characteristics to its original protein in its original animal host and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions.
All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable. Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Learn more in our guide “How active proteins work”.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.