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▼Active Proteins
AAA Biotech also known as AAA Bio or AAABio provides a variety of high-quality recombinant and natural/native proteins that are proven to work in a wide range of experiments. Explore our products to find the active protein that best fits your needs or experimental model.
Viewing 50-100 of 2567 product results
Application Data
(Immobilized Recombinant SARS-CoV-2 Envelope at 2ug/mL (100 uL/well) can bind Recombinant SARS-CoV-2 Nucleocapsid with a linear range of 1.2-41.1 ng/mL.)
COVID 19 Envelope Coronavirus, Active Protein (Cat# AAA28309)
Full Name
Recombinant SARS-CoV-2 Envelope Protein
Purity
> 95% by SDS-PAGE.
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
Alpha-enolase, Active Protein (Cat# AAA11794)
Full Name
Alpha-enolase, 1-434aa, Human, E Coli (Bioactivity Validated)
Gene Names
ENO1; NNE; PPH; MPB1; ENO1L1; HEL-S-17
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
WB (Western Blot)
(Western Blot: Spike RBD HIS Tag detected with Anti-HIS-Tag antibody HRP conjugate showing a band at approx. 30 kDa)
COVID 19 Spike Glycoprotein S1 RBD Coronavirus, Active Protein (Cat# AAA13473)
Full Name
Recombinant Human SARS-CoV-2 Spike Glycoprotein S1 RBD (HEK)
Purity
Affinity chromatography. Purity: >95% by SDS PAGE gel
Pricing
Purity
(The purity of LRRK2 (I2020T) was determined to be >70% by densitometry, approx. MW 210 kDa.)
LRRK2, Active Protein (Cat# AAA14255)
Full Name
LRRK2 Mutant (I2020T), Active
Gene Names
LRRK2; PARK8; RIPK7; ROCO2; AURA17; DARDARIN
Purity
>70%
Pricing
MHC class I chain-related gene B, Active Protein (Cat# AAA10837)
Full Name
Recombinant Human MHC class I chain-related gene B
Gene Names
MICB; PERB11.2
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
Actin, beta Human, Active Protein (Cat# AAA14745)
Full Name
Actin, beta Human
Gene Names
ACTB; BRWS1; PS1TP5BP1
Applications
EL/EIA, WB
Purity
>99%. May contain traces of gamma-actin.
Pricing
Sonic HedgeHog, Active Protein (Cat# AAA10853)
Full Name
Recombinant Mouse Sonic HedgeHog
Gene Names
Shh; Hx; Dsh; Hhg1; Hxl3; M100081; 9530036O11Rik
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing
Human Alanine Aminotransferase, Active Protein (Cat# AAA14927)
Full Name
Recombinant Human Alanine Aminotransferase Glutamie-Pyruvic Transaminase (EC 2.6.1.2)
Pricing
Trefoil Factor-3, Active Protein (Cat# AAA10881)
Full Name
Recombinant Human Trefoil Factor-3
Gene Names
TFF3; ITF; P1B; TFI
Purity
Greater than 97.0% as determined by SDS-PAGE.
Pricing
Matrix Metalloproteinase-3, Active Protein (Cat# AAA10817)
Full Name
Recombinant Human Matrix Metalloproteinase-3, HEK
Gene Names
MMP3; SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
Streptokinase, Active Protein (Cat# AAA10820)
Full Name
Recombinant Streptokinase
Purity
Greather than 97% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-PAGE
Pricing
Alkaline Phosphatase, Active Protein (Cat# AAA11487)
Full Name
Alkaline Phosphatase (CIP/CIAP), Calf Intestinal
Purity
Purified
Pricing
Mucin 16, Active Protein (Cat# AAA14758)
Full Name
Mucin 16, Recombinant, Human (CA125, FLJ14303, Ovarian Carcinoma Antigen CA 125)
Gene Names
MUC16; CA125
Purity
Purified
90% as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: <1EU/ug protein (LAL)
90% as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: <1EU/ug protein (LAL)
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
ALDH2, Active Protein (Cat# AAA11764)
Full Name
ALDH2,18-517aa, Human, E Coli (Bioactivity Validated)
Gene Names
ALDH2; ALDM; ALDHI; ALDH-E2
Reactivity
Human
Applications
SDS-PAGE, Enzyme Activity
Purity
> 90% by SDS-PAGE
Pricing
SDS-PAGE
COVID 19 Spike Protein, Biotinylated (RBD-SD1, Avi) Coronavirus, Active Protein (Cat# AAA22155)
Full Name
Recombinant 2019-nCoV Spike Protein (RBD-SD1, Avi-His Tag)(Active)
Purity
> 95 % as determined by reducing SDS-PAGE.
Pricing
Alkaline Phosphatase, Active Protein (Cat# AAA11488)
Full Name
Alkaline Phosphatase (ALP), Human Placental
Purity
Purified
Pricing
Bioactivity
(HTRF assay for AMPK Complex (A2+B2+G1) activity 1 uM STK S1 substrate was incubated with different concentrations of AMPK Complex (A2+B2+G1) protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 50 uM AMP and 100 ul ATP for 1 hr. The 10 ul detection reagents containing anti-STK antibody (1:100) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
AMPK Complex (A2+B2+G1), Active Protein (Cat# AAA60319)
Full Name
Recombinant AMPK Complex (A2+B2+G1) protein
Purity
>=90%
Pricing
Bioactivity
(HTRF assay for AMPK Complex (A1+B1+G2) activity 1 uM STK S1 substrate was incubated with different concentrations of AMPK Complex (A1+B1+G2) protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 50 uM AMP and 100 uM ATP for 1 hr. The 10 ul detection reagents containing anti-STK antibody (1:100) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
AMPK Complex (A1+B1+G2), Active Protein (Cat# AAA60344)
Full Name
Recombinant AMPK Complex (A1+B1+G2) protein
Purity
>=80%
Pricing
Transferrin, Active Protein (Cat# AAA10866)
Full Name
Recombinant Human Transferrin
Gene Names
TF; TFQTL1; PRO1557; PRO2086
Purity
Purity as determined by SDS-PAGE is 97%.
Pricing
Interleukin 6, Active Protein (Cat# AAA14805)
Full Name
Interleukin 6, Recombinant, Human (IL-6)
Gene Names
Il6; ILg6; Ifnb2
Purity
> 85% pure by SDS gel electrophoresis.
Pricing
Bioactivity
(HTRF assay for AMPK Complex (A2+B2+G2) activity 1 uM STK S1 substrate was incubated with different concentrations of AMPK Complex (A2+B2+G2) protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 50 uM AMP and 100 uM ATP for 1 hr. The 10 ul detection reagents containing anti-STK antibody (1:100) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
AMPK Complex (A2+B2+G2), Active Protein (Cat# AAA60320)
Full Name
Recombinant AMPK Complex (A2+B2+G2) protein
Purity
>=90%
Pricing
CD32a (FcgRIIa), Active Protein (Cat# AAA14417)
Full Name
Human CD32a Recombinant (FcgRIIa)
Purity
>95%, as determined by SDS-PAGE and HPLC
Pricing
West Nile Virus E, Active Protein (Cat# AAA24010)
Full Name
West Nile Virus E protein (His tag)
Applications
Western Blot
Purity
> 95% pure
Pricing
super leptin antagonist, Active Protein (Cat# AAA13623)
Full Name
Mouse super leptin antagonist (mutant D23/L39A/D40A/F41A)
Purity
The purity of mouse super-active leptin antagonist is greater than 98.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
Peroxiredoxin-1, Active Protein (Cat# AAA10855)
Full Name
Recombinant Human Peroxiredoxin-1
Gene Names
PRDX1; PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A
Purity
Greater than 90.0% as determined by SDS-PAGE.
Pricing
IL-11 receptor alpha, Active Protein (Cat# AAA14431)
Full Name
Mouse IL-11 receptor alpha Recombinant
Purity
>85%, as determined by SDS-PAGE and HPLC
Pricing
Neuregulin-4, Active Protein (Cat# AAA14428)
Full Name
Human Neuregulin-4 Recombinant
Purity
>96% as determined by SDS-PAGE and HPLC
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Neuron-Specific Enolase (NSE), Active Protein (Cat# AAA11754)
Full Name
Neuron-Specific Enolase (NSE), 1-434aa, Human, E Coli (Bioactivity Validated)
Gene Names
ENO2; NSE; HEL-S-279
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Bioactivity
SDS-PAGE
(The purity was determined to be >85% by densitometry. Approx. MW 85-100 kDa.)
IRAK1, Active Protein (Cat# AAA73158)
Full Name
IRAK1 (catalytic domain), Active
Purity
>85%
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomasie blue stain)
PTP-1B (Protein Tyrosine Phosphatase1B), Active Protein (Cat# AAA11740)
Full Name
PTP-1B (Protein Tyrosine Phosphatase1B), 1-321aa, Human, E Coli (Bioactivity Validated)
Gene Names
PTPN1; PTP1B
Applications
Enzyme Activity, SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Application Data
(Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in tau fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau monomers. A greater increase in fluorescence is seen when 50 uM monomer is combined with 10 uM PFFs, as the fibrils seed the formation of new fibrils from the pool of monomers. Thioflavin T ex = 450 nm, em = 485 nm.)
Tau441, Active Protein (Cat# AAA253967)
Full Name
Active Human Recombinant Tau441 (2N4R), P301S Mutant Protein Monomer
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103
Applications
Western Blot
Purity
>95%
Ion-Exchange Purified
Ion-Exchange Purified
Pricing
CD22, Active Protein (Cat# AAA14393)
Full Name
CD22 protein
Gene Names
CD22; SIGLEC2; SIGLEC-2
Purity
> 98% by SDS-PAGE and HPLC analyses
Pricing
IFN ALPHA, Active Protein (Cat# AAA12301)
Full Name
RECOMBINANT CHICKEN INTERFERON ALPHA
Gene Names
IFNA3; IFNA; IFNA1; IFNA2; IFNA6; IFN-alpha; IFN-gamma
Applications
Functional Assay
Purity
>85% by Ni chelate chromatography
Pricing
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.)
NQO1, Active Protein (Cat# AAA11735)
Full Name
Recombinant Human NQO1 Protein
Gene Names
NQO1; DTD; QR1; DHQU; DIA4; NMOR1; NMORI
Applications
SDS-PAGE, ELISA
Purity
>95% by SDS-PAGE
Pricing
GDF11, Active Protein (Cat# AAA14381)
Full Name
GDF11 protein
Gene Names
GDF11; BMP11; BMP-11
Purity
> 98% by SDS-PAGE analysis and HPLC
Pricing
Application Data
COVID 19 Spike S1 Coronavirus, Active Protein (Cat# AAA60537)
Full Name
SARS-CoV-2 Spike S1 protein
Purity
>95%
Pricing
Bioactivity
(Sample Activity Plot.)
COVID 19 Spike S1 Coronavirus, Active Protein (Cat# AAA73161)
Full Name
2019-nCoV Spike Protein S1
Pricing
SDS_PAGE
(SDS-PAGE of ~15 kDa Active Human Tau Protein K18 P301L Preformed Fibrils. Lane 1: MW Ladder. Lane 2: Tau Protein Preformed Fibrils.)
Tau, Active Protein (Cat# AAA253968)
Full Name
Active Human Recombinant Tau (K18), P301L Mutant Protein Preformed Fibrils
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; PPP1R103
Applications
Western Blot
Purity
>95%
Ion-Exchange Purified
Ion-Exchange Purified
Pricing
Bioactivity
(HTRF assay for NTRK1 (440-796) activity 1 uM TK substrate was incubated with different concentrations of NTRK1 (440-796) protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, and 100 uM ATP for 1 hour. Then 10 ul detection reagents containing anti-TK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
NTRK1, Active Protein (Cat# AAA60324)
Full Name
Recombinant NTRK1 (440-796) protein
Purity
>=90%
Pricing
HVEM-Fc, Active Protein (Cat# AAA14394)
Full Name
HVEM-Fc protein
Purity
>= 98% by SDS-PAGE and HPLC
Pricing
Purity
(The purity of PDE1B was determined to be >90% by densitometry. Approx. MW 86kDa)
PDE1B, Active Protein (Cat# AAA73094)
Full Name
PDE1B, Active
Gene Names
PDE1B; PDE1B1; PDES1B; HEL-S-79p
Purity
>90%
Pricing
Bioactivity
(HTRF assay for AMPK Complex (A1+B2+G2) activity 1 uM STK S1 substrate was incubated with different concentrations of AMPK Complex (A1+B2+G2) protein in a 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT, 50 uM AMP and 100 uM ATP for 1 hr. The 10 ul detection reagents containing anti-STK antibody (1:100) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
AMPK Complex (A1+B2+G2), Active Protein (Cat# AAA60318)
Full Name
Recombinant AMPK Complex (A1+B2+G2) protein
Purity
>=90%
Pricing
Bioactivity
(HTRF Assay for Recombinant YES1 activity. 1 uM TK substrate was incubated with different concentrations of YES1 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-TK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
SDS-PAGE
UCHL1, Active Protein (Cat# AAA257988)
Full Name
UCHL1 Protein, Human, Recombinant (His Tag)
Gene Names
UCHL1; PARK5; PGP95; PGP9.5; Uch-L1; PGP 9.5
Purity
>92% as determined by SDS-PAGE
Pricing
Bioactivity
WB (Western Blot)
(Sample: Recombinant GAS6, Human;Antibody: Rabbit Anti-Human GAS6 Ab)
Growth Arrest Specific Protein 6 (GAS6), Active Protein (Cat# AAA21055)
Full Name
Active Growth Arrest Specific Protein 6 (GAS6)
Gene Names
GAS6; AXSF; AXLLG
Reactivity
Homo sapiens (Human)
Applications
Cell Culture, Activity Assay
Purity
>92%
Pricing
Bioactivity
(HTRF Assay for Recombinant PAK4 activity. 1 uM STK S2 substrate was incubated with different concentrations of PAK4 protein in 10 ul reaction system containing 1×Enzymatic Buffer, 5 mM MgCl2, 1 mM DTT and 100 uM ATP for 1 hour. The 10 ul detection reagents containing anti-STK antibody (1:2) and SA-XL665 (1:100) diluted with 1× Detection Buffer were added and incubated with the reactions for 30 min. All the operations and reactions were performed at room temperature. HTRF assay was used for detection.)
SDS-PAGE
Glutathione S-Transferase (GST), Active Protein (Cat# AAA48483)
Full Name
Glutathione S-Transferase (GST), 1-218 aa, Schistosoma japonicum E Coli (Bioactivity Validated)
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
Bioactivity
(HTRF assay for Recombinant SETDB1 protein activity. 1 uM histone peptide H3 (1-21) was incubated with SETDB1 in reaction buffer including 50 mM Tris-HCl pH 8.6, 0.02% Triton X-100, 2 mM MgCl2, 1 mM TCEP and 50 uM SAM for 3 hours at room temperature. H3K9me2 antibody was used to detect reaction product.)
What Are Active Proteins?
Proteins are large molecules made up of long chains of amino acids.
They will typically fold into a very particular 3-dimensional shape/conformation, that is sometimes referred to as their “native” form, which allows them to work properly in the body. For the purposes of product categorization, AAA Biotech will typically refer to proteins purified from their original animal host as being “native” proteins (this is to signify their difference compared to their “recombinant” or “synthetic” protein counterparts).
If a protein successfully folds into the correct shape, it is will typically display high fidelity characteristics to its original protein in its original animal host, and be classified as an active protein, as it will be able to function “normally” in most enzymatic or binding capacities. If it loses this shape, due to factors such as heat or strong chemicals (such as detergents), it becomes inactive and is no longer able to perform its basic functions. All of the proteins in this category are made under strict quality control, and they are active, pure, low in contaminants, and stable.
Most are stored as freeze-dried powders and come without extra tags, so they’re very close to the actual natural/native form.
Key Applications of Active Proteins
1. Scientific Research
- Aid in the study of how proteins function in the body
- Aid in understanding various disease processes
2. Drug Development
- Powerful tools to investigate how potential drugs interact with specific proteins
- Ideal for identifying drug targets
3. Cell Culture
- Are routinely utilized to support cell growth and function (e.g., using exogenous growth factors)
- Can be used to promote cellular development into specific types (differentiation)
4. Diagnostics
- Regularly utilized in tests to detect diseases or infections (e.g., COVID-19, cancer)
- Note: All products are strictly for research-use only (RUO).
5. Therapeutics
- Some active proteins are used directly as treatments (e.g., insulin, enzymes)
- Note: All products are strictly for research-use only (RUO).
6. Vaccine Development
- Used to create or test vaccines by mimicking parts of viruses or bacteria
7. Biochemical Assays
- They can facilitate the characterization of enzyme activity, binding strength, or protein interactions in lab tests
Why Buy Active Proteins from AAA Biotech?
- High biological activity – Verified to perform as expected or indicated on datasheet
- Strict quality control – We are confident in our active proteins’ reliability and consistency
- High purity & low endotoxin – Ideal for applications involving sensitive or precious samples/components
- Freeze-dried for stability – Long shelf life and straightforward storage
- Mostly tag-free – Closer to natural/native protein form
FAQ
1. What are active proteins used for in research?
Active proteins are used primarily in the study of how proteins function, in characterizing/discovering drug interactions, supporting cell growth, running biochemical assays, and in development of diagnostics or therapeutics.
2. How are AAA Biotech's active proteins validated?
AAA Biotech’s active proteins are validated through strict quality control and functional assays to ensure they are properly folded and active. “Active”, though, can be an ambiguous term, so if a specific “activity” or “binding” capability of a protein is of crucial interest to you, please inquire with us prior to purchase, and we will provide further details on how the “Active” modifier was determined to be applicable.
3. Are these proteins tested for biological activity?
Yes, all active proteins from AAA Biotech are tested to confirm they have the expected biological activity before being offered for use. Though, said “biological activity” can be either “enzymatic”, “binding”, or both.